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26.

34603
Accesses

Method   Open Access Highly Accessed

Differential expression analysis for sequence count data

Simon Anders, Wolfgang Huber Genome Biology 2010, 11:R106 (27 October 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment | F1000 Biology |  Editor’s summary

DEseq allows the determination of differential expression of read count data from RNA-seq or ChIP-seq experiments

27.

34190
Accesses

Research article   Open Access Highly Accessed

Mental illness related disparities in diabetes prevalence, quality of care and outcomes: a population-based longitudinal study

Qun Mai, C D'Arcy J Holman, Frank M Sanfilippo, Jonathan D Emery, David B Preen BMC Medicine 2011, 9:118 (1 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Disparities in diabetes prevalence and the quality and outcome of diabetic care of those with mental illness and those without in Australia highlights the need for better, more integrated care for this population.

28.

33109
Accesses

Review   Open Access Highly Accessed

A review of fatty acid profiles and antioxidant content in grass-fed and grain-fed beef

Cynthia A Daley, Amber Abbott, Patrick S Doyle, Glenn A Nader, Stephanie Larson Nutrition Journal 2010, 9:10 (10 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

29.

32816
Accesses

Review   Open Access Highly Accessed

Nutrition and cancer: A review of the evidence for an anti-cancer diet

Michael S Donaldson Nutrition Journal 2004, 3:19 (20 October 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

30.

32808
Accesses

Research article   Open Access Highly Accessed

Effect of an electronic nicotine delivery device (e-Cigarette) on smoking reduction and cessation: a prospective 6-month pilot study

Riccardo Polosa, Pasquale Caponnetto, Jaymin B Morjaria, Gabriella Papale, Davide Campagna, Cristina Russo BMC Public Health 2011, 11:786 (11 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

31.

32354
Accesses

Software   Open Access Highly Accessed

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Ben Langmead, Cole Trapnell, Mihai Pop, Steven L Salzberg Genome Biology 2009, 10:R25 (4 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Bowtie: a new ultrafast memory-efficient tool for the alignment of short DNA sequence reads to large genomes.

32.

32170
Accesses

Review   Open Access Highly Accessed

Applications of nanoparticles in biology and medicine

OV Salata Journal of Nanobiotechnology 2004, 2:3 (30 April 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

33.

32126
Accesses

Research   Open Access Highly Accessed

The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide

Monica H Carlsen, Bente L Halvorsen, Kari Holte, Siv K Bøhn, Steinar Dragland, Laura Sampson, Carol Willey, Haruki Senoo, Yuko Umezono, Chiho Sanada, Ingrid Barikmo, Nega Berhe, Walter C Willett, Katherine M Phillips, David R Jacobs, Rune Blomhoff Nutrition Journal 2010, 9:3 (22 January 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

34.

32100
Accesses

Technical advance   Open Access Highly Accessed

A new growth chart for preterm babies: Babson and Benda's chart updated with recent data and a new format

Tanis R Fenton BMC Pediatrics 2003, 3:13 (16 December 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

35.

31820
Accesses

Commentary   Open Access Highly Accessed

International Society of Sports Nutrition position stand: creatine supplementation and exercise

Thomas W Buford, Richard B Kreider, Jeffrey R Stout, Mike Greenwood, Bill Campbell, Marie Spano, Tim Ziegenfuss, Hector Lopez, Jamie Landis, Jose Antonio Journal of the International Society of Sports Nutrition 2007, 4:6 (30 August 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

36.

31774
Accesses

Review   Open Access Highly Accessed

Cutaneous lesions of the external ear

Michael Sand, Daniel Sand, Dominik Brors, Peter Altmeyer, Benno Mann, Falk G Bechara Head & Face Medicine 2008, 4:2 (8 February 2008)

Abstract | Full text | PDF | PubMed

37.

31730
Accesses

Commentary   Open Access Highly Accessed

A tutorial on pilot studies: the what, why and how

Lehana Thabane, Jinhui Ma, Rong Chu, Ji Cheng, Afisi Ismaila, Lorena P Rios, Reid Robson, Marroon Thabane, Lora Giangregorio, Charles H Goldsmith BMC Medical Research Methodology 2010, 10:1 (6 January 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

38.

31649
Accesses

Research   Open Access Highly Accessed

Hookah smoking and cancer: carcinoembryonic antigen (CEA) levels in exclusive/ever hookah smokers

Khan Sajid, Kamal Chaouachi, Rubaida Mahmood Harm Reduction Journal 2008, 5:19 (24 May 2008)

Abstract | Full text | PDF | PubMed | 8 comments

39.

31013
Accesses

Review   Open Access Highly Accessed

Molecular dynamics simulations and drug discovery

Jacob D Durrant, J Andrew McCammon BMC Biology 2011, 9:71 (28 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Modeling the movements of atoms within macromolecules can predict their conformational flexibility to inform drug discovery. Jacob Durrant and Andrew McCammon explain how this is done in molecular dynamics simulations, reviewing both the successes and current limitations of the approach.

40.

30984
Accesses

Review   Open Access Highly Accessed

Weight Science: Evaluating the Evidence for a Paradigm Shift

Linda Bacon, Lucy Aphramor Nutrition Journal 2011, 10:9 (24 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

41.

30983
Accesses

Research   Open Access Highly Accessed

Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group

Rinaldo Bellomo, Claudio Ronco, John A Kellum, Ravindra L Mehta, Paul Palevsky, the ADQI workgroup Critical Care 2004, 8:R204-R212 (24 May 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment | F1000

42.

30173
Accesses

Review   Open Access Highly Accessed

Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolism

Tyler A Churchward-Venne, Nicholas A Burd, Stuart M Phillips Nutrition & Metabolism 2012, 9:40 (17 May 2012)

Abstract | Full text | PDF | PubMed

43.

29956
Accesses

Research   Open Access Highly Accessed

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe, Frank Speleman Genome Biology 2002, 3:research0034-research0034.11 (18 June 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Using real-time reverse transcription PCR ten housekeeping genes from different abundance and functional classes in various human tissues were evaluated. The conventional use of a single gene for normalization leads to relatively large errors in a significant proportion of samples tested.

44.

29875
Accesses

Review   Open Access Highly Accessed

Nutritional therapies for mental disorders

Shaheen E Lakhan, Karen F Vieira Nutrition Journal 2008, 7:2 (21 January 2008)

Abstract | Full text | PDF | PubMed | 1 comment

45.

29516
Accesses

Review   Open Access Highly Accessed

Fructose, insulin resistance, and metabolic dyslipidemia

Heather Basciano, Lisa Federico, Khosrow Adeli Nutrition & Metabolism 2005, 2:5 (21 February 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

46.

29208
Accesses

Research   Open Access Highly Accessed

The health impacts of globalisation: a conceptual framework

Maud MTE Huynen, Pim Martens, Henk BM Hilderink Globalization and Health 2005, 1:14 (3 August 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

47.

28832
Accesses

Commentary   Open Access Highly Accessed

International Society of Sports Nutrition position stand: protein and exercise

Bill Campbell, Richard B Kreider, Tim Ziegenfuss, Paul La Bounty, Mike Roberts, Darren Burke, Jamie Landis, Hector Lopez, Jose Antonio Journal of the International Society of Sports Nutrition 2007, 4:8 (26 September 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

48.

28622
Accesses

Review   Open Access Highly Accessed

Protein timing and its effects on muscular hypertrophy and strength in individuals engaged in weight-training

Matthew Stark, Judith Lukaszuk, Aimee Prawitz, Amanda Salacinski Journal of the International Society of Sports Nutrition 2012, 9:54 (14 December 2012)

Abstract | Full text | PDF | PubMed

49.

28251
Accesses

Methodology article   Open Access Highly Accessed

Statistical analysis of real-time PCR data

Joshua S Yuan, Ann Reed, Feng Chen, C Neal Stewart BMC Bioinformatics 2006, 7:85 (22 February 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

50.

28197
Accesses

Review   Open Access Highly Accessed

Rate of complications in scoliosis surgery – a systematic review of the Pub Med literature

Hans-Rudolf Weiss, Deborah Goodall Scoliosis 2008, 3:9 (5 August 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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