BioMed Central | Most Viewed

Submit a manuscript Register Contact us

Advertisement

Articles

Display/download options Articles per page: 25 | 50 | 100

Display options

Editor's summary Citation

Download options

Send
To

	All
	1. 13150 Accesses	Research article scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs Gregory R Leong, Karen R Goulding, Nancy Amin, Helena E Richardson, Anthony M Brumby BMC Biology 2009, 7:62 (24 September 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary Scribble, a cell polarity regulator in Drosophila, represses tumorigenesis by inhibiting atypical protein kinase C and Jun N-terminal kinase-dependent pathways, and this might be relevant for how human Scrib restrains oncogene-mediated transformation.
	2. 9500 Accesses	Research article Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes Mari Palgi, Dario Greco, Riitta Lindström, Petri Auvinen, Tapio I Heino BMC Genomics 2012, 13:134 (11 April 2012) Abstract \| Full text \| PDF \| PubMed
	3. 8652 Accesses	Review Nutrient timing revisited: is there a post-exercise anabolic window? Alan Albert Aragon, Brad Jon Schoenfeld Journal of the International Society of Sports Nutrition 2013, 10:5 (29 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A different look at the science of nutrient timing.
	4. 7221 Accesses	Research Characterizing and measuring bias in sequence data Michael G Ross, Carsten Russ, Maura Costello, Andrew Hollinger, Niall J Lennon, Ryan Hegarty, Chad Nusbaum, David B Jaffe Genome Biology 2013, 14:R51 (29 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A comparison of the bias in sequencing data from four different platforms reveals that some human promoters are completelymissed
	5. 6671 Accesses	Research article Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition Sabine Rohrmann, Kim Overvad, H Bueno-de-Mesquita, Marianne U Jakobsen, Rikke Egeberg, Anne Tjønneland, Laura Nailler, Marie-Christine Boutron-Ruault, Françoise Clavel-Chapelon, Vittorio Krogh, Domenico Palli, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Manuela M Bergmann, Heiner Boeing, Kuanrong Li, Rudolf Kaaks, Kay-Tee Khaw, Nicholas J Wareham, Francesca L Crowe, Timothy J Key, Androniki Naska, Antonia Trichopoulou, Dimitirios Trichopoulos, Max Leenders, Petra HM Peeters, Dagrun Engeset, Christine L Parr, Guri Skeie et al. BMC Medicine 2013, 11:63 (7 March 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments \| Editor’s summary A large study finds a positive association between processed meat consumption and mortality due to cardiovascular disease and cancer, indicating that reducing the amount of processed meat in the diet could reduce mortality risk.
	6. 5980 Accesses	Review Gene regulation by the act of long non-coding RNA transcription Aleksandra E Kornienko, Philipp M Guenzl, Denise P Barlow, Florian M Pauler BMC Biology 2013, 11:59 (30 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Florian Pauler, Denise Barlow and colleagues review the evidence on long non-protein-coding RNAs for which the process of transcription itself functions in the regulation of nearby genes, but the RNA product may be irrelevant.
	7. 5857 Accesses	Review Ketogenic diets and physical performance Stephen D Phinney Nutrition & Metabolism 2004, 1:2 (17 August 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	8. 5809 Accesses	Research article The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild Javier Prado-Martinez, Irene Hernando-Herraez, Belen Lorente-Galdos, Marc Dabad, Oscar Ramirez, Carlos Baeza-Delgado, Carlos Morcillo-Suarez, Can Alkan, Fereydoun Hormozdiari, Emanuele Raineri, Jordi Estellé, Marcos Fernandez-Callejo, Mònica Valles, Lars Ritscher, Torsten Schöneberg, Elisa de la Calle-Mustienes, Sònia Casillas, Raquel Rubio-Acero, Marta Melé, Johannes Engelken, Mario Caceres, Jose Gomez-Skarmeta, Marta Gut, Jaume Bertranpetit, Ivo G Gut, Teresa Abello, Evan E Eichler, Ismael Mingarro, Carles Lalueza-Fox, Arcadi Navarro, Tomas Marques-Bonet et al. BMC Genomics 2013, 14:363 (31 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A phenotypically unique gorilla carries a private non-synonymous substitution in a transmembrane domain in SLC45A2, one of the candidate genes associated with the OCA4 class of albinism
	9. 5792 Accesses	Research article A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers Michael A Quail, Miriam Smith, Paul Coupland, Thomas D Otto, Simon R Harris, Thomas R Connor, Anna Bertoni, Harold P Swerdlow, Yong Gu BMC Genomics 2012, 13:341 (24 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Sequencing of four microbial genomes with widely differing GC content is compared on performance using three major new platforms: Ion Torrent PGM, Pacific Biosciences RS, and illumina MiSeq versus Illumina HiSeq system.
	10. 5741 Accesses	Research article Does long-term creatine supplementation impair kidney function in resistance-trained individuals consuming a high-protein diet? Rebeca Lugaresi, Marco Leme, Vítor de Salles Painelli, Igor Murai, Hamilton Roschel, Marcelo Sapienza, Antonio Lancha Junior, Bruno Gualano Journal of the International Society of Sports Nutrition 2013, 10:26 (16 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary More evidence to show that creatine is safe.
	11. 5254 Accesses	Research Management of bleeding and coagulopathy following major trauma: an updated European guideline Donat R Spahn, Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Daniela Filipescu, Beverley J Hunt, Radko Komadina, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Jean-Louis Vincent, Rolf Rossaint Critical Care 2013, 17:R76 (19 April 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The Task Force for Advanced Bleeding Care in Trauma have updated their guidelines on the management of bleeding following traumatic injury, with new recommendations addressing changes made in clinical care.
	12. 4936 Accesses	Review Food Advertising and Marketing Directed at Children and Adolescents in the US Mary Story, Simone French International Journal of Behavioral Nutrition and Physical Activity 2004, 1:3 (10 February 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	13. 4823 Accesses	Research The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color Juan C Motamayor, Keithanne Mockaitis, Jeremy Schmutz, Niina Haiminen, Donald Livingstone, Omar Cornejo, Seth D Findley, Ping Zheng, Filippo Utro, Stefan Royaert, Christopher Saski, Jerry Jenkins, Ram Podicheti, Meixia Zhao, Brian E Scheffler, Joseph C Stack, Frank A Feltus, Guiliana M Mustiga, Freddy Amores, Wilbert Phillips, Jean Philippe Marelli, Gregory D May, Howard Shapiro, Jianxin Ma, Carlos D Bustamante, Raymond J Schnell, Dorrie Main, Don Gilbert, Laxmi Parida, David N Kuhn et al. Genome Biology 2013, 14:R53 (3 June 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary The genome sequence of Theobroma cacao Matina 1-6 allows the identification of a gene associated with pod color
	14. 4541 Accesses	Review Machine learning and genome annotation: a match meant to be? Kevin Y Yip, Chao Cheng, Mark Gerstein Genome Biology 2013, 14:205 (29 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Mark Gerstein, Kevin Yip and Chao Cheng present a beginner's guide to machine learning for genome annotation
	15. 4321 Accesses	Review Dietary protein intake and renal function William F Martin, Lawrence E Armstrong, Nancy R Rodriguez Nutrition & Metabolism 2005, 2:25 (20 September 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	16. 4276 Accesses	Review Physical education, school physical activity, school sports and academic performance François Trudeau, Roy J Shephard International Journal of Behavioral Nutrition and Physical Activity 2008, 5:10 (25 February 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	17. 4150 Accesses	Software REAPR: a universal tool for genome assembly evaluation Martin Hunt, Taisei Kikuchi, Mandy Sanders, Chris Newbold, Matthew Berriman, Thomas D Otto Genome Biology 2013, 14:R47 (27 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A new user-friendly software tool for genome assembly evaluation
	18. 4040 Accesses	Review Cancer as a metabolic disease Thomas N Seyfried, Laura M Shelton Nutrition & Metabolism 2010, 7:7 (27 January 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	19. 3929 Accesses	Opinion Spectrum of gluten-related disorders: consensus on new nomenclature and classification Anna Sapone, Julio C Bai, Carolina Ciacci, Jernej Dolinsek, Peter HR Green, Marios Hadjivassiliou, Katri Kaukinen, Kamran Rostami, David S Sanders, Michael Schumann, Reiner Ullrich, Danilo Villalta, Umberto Volta, Carlo Catassi, Alessio Fasano BMC Medicine 2012, 10:13 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Fasano and colleagues propose new nomenclature and classifications within the spectrum of gluten-related disorders (GRDs), prompted by indications from the past decade that reactions to gluten may be caused by conditions other than celiac disease.
	20. 3978 Accesses	Research Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance David Martino, Yuk Jin Loke, Lavinia Gordon, Miina Ollikainen, Mark N Cruickshank, Richard Saffery, Jeffrey M Craig Genome Biology 2013, 14:R42 (22 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A longitudinal study of DNA methylation in twins at birth and 18 months finds that some loci drift in methylation status
	21. 3962 Accesses	Review Childhood obesity, prevalence and prevention Mahshid Dehghan, Noori Akhtar-Danesh, Anwar T Merchant Nutrition Journal 2005, 4:24 (2 September 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments
	22. 3920 Accesses	Debate A theory of organizational readiness for change Bryan J Weiner Implementation Science 2009, 4:67 (19 October 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23. 3894 Accesses	Method TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions Daehwan Kim, Geo Pertea, Cole Trapnell, Harold Pimentel, Ryan Kelley, Steven L Salzberg Genome Biology 2013, 14:R36 (25 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A major update to TopHat, the popular Bowtie-based spliced aligner
	24. 3835 Accesses	Review ISSN exercise & sport nutrition review: research & recommendations Richard B Kreider, Colin D Wilborn, Lem Taylor, Bill Campbell, Anthony L Almada, Rick Collins, Mathew Cooke, Conrad P Earnest, Mike Greenwood, Douglas S Kalman, Chad M Kerksick, Susan M Kleiner, Brian Leutholtz, Hector Lopez, Lonnie M Lowery, Ron Mendel, Abbie Smith, Marie Spano, Robert Wildman, Darryn S Willoughby, Tim N Ziegenfuss, Jose Antonio Journal of the International Society of Sports Nutrition 2010, 7:7 (2 February 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	25. 3658 Accesses	Research article Human milk metagenome: a functional capacity analysis Tonya L Ward, Sergey Hosid, Ilya Ioshikhes, Illimar Altosaar BMC Microbiology 2013, 13:116 (25 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	26. 3622 Accesses	Study protocol ACHESS – The Australian study of child health in same-sex families: background research, design and methodology Simon Crouch, Elizabeth Waters, Ruth McNair, Jennifer Power, Elise Davis BMC Public Health 2012, 12:646 (13 August 2012) Abstract \| Full text \| PDF \| PubMed
	27. 3576 Accesses	Research The effects of pre- and post-exercise consumption of multi-ingredient performance supplements on cardiovascular health and body fat in trained men after six weeks of resistance training: a stratified, randomized, double-blind study Michael J Ormsbee, Dennison Thomas, William Mandler, Emery G Ward, Amber W Kinsey, Lynn B Panton, Timothy P Scheett, Shirin Hooshmand, Emily Simonavice, Jeong-Su Kim Nutrition & Metabolism 2013, 10:39 (16 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	28. 3501 Accesses	Research Genome of the long-living sacred lotus (Nelumbo nucifera Gaertn.) Ray Ming, Robert VanBuren, Yanling Liu, Mei Yang, Yuepeng Han, Lei-Ting Li, Qiong Zhang, Min-Jeong Kim, Michael C Schatz, Michael Campbell, Jingping Li, John E Bowers, Haibao Tang, Eric Lyons, Ann A Ferguson, Giuseppe Narzisi, David R Nelson, Crysten E Blaby-Haas, Andrea R Gschwend, Yuannian Jiao, Joshua P Der, Fanchang Zeng, Jennifer Han, Xiang Jia Min, Karen A Hudson, Ratnesh Singh, Aleel K Grennan, Steven J Karpowicz, Jennifer R Watling, Kikukatsu Ito et al. Genome Biology 2013, 14:R41 (10 May 2013) Abstract \| Provisional PDF \| PubMed \| F1000 Biology \| Editor’s summary The genome of the long-living, slowly evolving sacred lotus reveals the genetic mechanisms underlying its adaptation to limited nutrient availability
	29. 3522 Accesses	Journal club critique Crystalloids vs. colloids: KO at the twelfth round? Dennis P Phillips, A Kaynar, John A Kellum, Hernando Gomez Critical Care 2013, 17:319 (29 May 2013) Abstract \| Full text \| PDF \| PubMed
	30. 3473 Accesses	Research The importance of human resources management in health care: a global context Stefane M Kabene, Carole Orchard, John M Howard, Mark A Soriano, Raymond Leduc Human Resources for Health 2006, 4:20 (27 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	31. 3454 Accesses	Review The potential role of phytochemicals in wholegrain cereals for the prevention of type-2 diabetes Damien P Belobrajdic, Anthony R Bird Nutrition Journal 2013, 12:62 (16 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	32. 3395 Accesses	Debate Wikis, blogs and podcasts: a new generation of Web-based tools for virtual collaborative clinical practice and education Maged Boulos, Inocencio Maramba, Steve Wheeler BMC Medical Education 2006, 6:41 (15 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	33. 3322 Accesses	Study protocol Causes and consequences of cerebral small vessel disease. The RUN DMC study: a prospective cohort study. Study rationale and protocol Anouk GW van Norden, Karlijn F de Laat, Rob AR Gons, Inge WM van Uden, Ewoud J van Dijk, Lucas JB van Oudheusden, Rianne AJ Esselink, Bastiaan R Bloem, Baziel GM van Engelen, Machiel J Zwarts, Indira Tendolkar, Marcel G Olde-Rikkert, Maureen J van der Vlugt, Marcel P Zwiers, David G Norris, Frank-Erik de Leeuw BMC Neurology 2011, 11:29 (28 February 2011) Abstract \| Full text \| PDF \| PubMed
	34. 3229 Accesses	Review Weight Science: Evaluating the Evidence for a Paradigm Shift Linda Bacon, Lucy Aphramor Nutrition Journal 2011, 10:9 (24 January 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	35. 3226 Accesses	Methodology Stool substitute transplant therapy for the eradication of Clostridium difficile infection: ‘RePOOPulating’ the gut Elaine O Petrof, Gregory B Gloor, Stephen J Vanner, Scott J Weese, David Carter, Michelle C Daigneault, Eric M Brown, Kathleen Schroeter, Emma Allen-Vercoe Microbiome 2013, 1:3 (9 January 2013) Abstract \| Full text \| PDF \| Editor’s summary A super-probiotic synthetic stool, composed of 33 different bacterial strains, was developed and used to treat two patients with severe C. difficile infection. The probiotic bacteria could still be detected up to six months after inoculation.
	36. 3191 Accesses	Technical advance A new growth chart for preterm babies: Babson and Benda's chart updated with recent data and a new format Tanis R Fenton BMC Pediatrics 2003, 3:13 (16 December 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	37. 3169 Accesses	Review Critical care management of severe traumatic brain injury in adults Samir H Haddad, Yaseen M Arabi Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012, 20:12 (3 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	38. 3128 Accesses	Research Amelioration of motor/sensory dysfunction and spasticity in a rat model of acute lumbar spinal cord injury by human neural stem cell transplantation Sebastiaan van Gorp, Marjolein Leerink, Osamu Kakinohana, Oleksandr Platoshyn, Camila Santucci, Jan Galik, Elbert A Joosten, Marian Hruska-Plochan, Danielle Goldberg, Silvia Marsala, Karl Johe, Joseph D Ciacci, Martin Marsala Stem Cell Research & Therapy 2013, 4:57 (28 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Human foetal stem cell grafts improve both motor and sensory functions in rats suffering from a spinal cord injury, demonstrating potential for cell replacement therapy in human spinal cord injuries.
	39. 3120 Accesses	Research An exploration of social and economic outcome and associated health-related quality of life after critical illness in general intensive care unit survivors: a 12-month follow-up study John Griffiths, Robert A Hatch, Judith Bishop, Kayleigh Morgan, Crispin Jenkinson, Brian H Cuthbertson, Stephen J Brett Critical Care 2013, 17:R100 (28 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Survivors of critical illness in the UK face a negative impact on employment and commonly have a care requirement after discharge from hospital.
	40. 3064 Accesses	Editorial Evolutionary medicine – the quest for a better understanding of health, disease and prevention Martin Brüne, Ze’ev Hochberg BMC Medicine 2013, 11:116 (29 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary In an editorial to launch our article collection on Evolutionary Medicine, Martin Brüne and Ze’ev Hochberg discuss the relevance of evolutionary medicine in clinical research as a means of ultimately gaining deeper understanding about human diseases.
	41. 3019 Accesses	Research article Effect of an electronic nicotine delivery device (e-Cigarette) on smoking reduction and cessation: a prospective 6-month pilot study Riccardo Polosa, Pasquale Caponnetto, Jaymin B Morjaria, Gabriella Papale, Davide Campagna, Cristina Russo BMC Public Health 2011, 11:786 (11 October 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	42. 2982 Accesses	Research A novel virus genome discovered in an extreme environment suggests recombination between unrelated groups of RNA and DNA viruses Geoffrey S Diemer, Kenneth M Stedman Biology Direct 2012, 7:13 (19 April 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The discovery of a previously unknown viral genome, the apparent result of a recombination event between unrelated RNA and DNA viruses, has implications for theories of viral evolution.
	43. 2977 Accesses	Research The plasticity of the grapevine berry transcriptome Silvia Santo, Giovanni Tornielli, Sara Zenoni, Marianna Fasoli, Lorenzo Farina, Andrea Anesi, Flavia Guzzo, Massimo Delledonne, Mario Pezzotti Genome Biology 2013, 14:r54 (10 June 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A transcriptomic and metabolomic analysis of the plasticity of grapevine berry gene expression in response to development and the environment
	44. 2970 Accesses	Research highlight New gene expression pipelines gush lncRNAs Jiashi Wang, Bronwyn A Lucas, Lynne E Maquat Genome Biology 2013, 14:117 (24 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The characterization of lncRNA expression during neuronal development is a useful resource for elucidating the functions of non-coding transcripts
	45. 2968 Accesses	Commentary International Society of Sports Nutrition position stand: protein and exercise Bill Campbell, Richard B Kreider, Tim Ziegenfuss, Paul La Bounty, Mike Roberts, Darren Burke, Jamie Landis, Hector Lopez, Jose Antonio Journal of the International Society of Sports Nutrition 2007, 4:8 (26 September 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	46. 2952 Accesses	Question and Answer Q&A: Antibiotic resistance: what more do we know and what more can we do? Gerard D Wright BMC Biology 2013, 11:51 (17 May 2013) Full text \| PDF \| PubMed \| Editor’s summary Antibiotic resistance is both an ancient phenomenon and a worsening medical problem. Gerard Wright explains why, and what should be done about it.
	47. 2948 Accesses	Research Decreased tryptophan metabolism in patients with autism spectrum disorders Luigi Boccuto, Chin-Fu Chen, Ayla R Pittman, Cindy D Skinner, Heather J McCartney, Kelly Jones, Barry R Bochner, Roger E Stevenson, Charles E Schwartz Molecular Autism 2013, 4:16 (3 June 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	48. 2925 Accesses	Comment Open questions: A logic (or lack thereof) of genome organization Laurence D Hurst BMC Biology 2013, 11:58 (28 May 2013) Full text \| PDF \| PubMed \| Editor’s summary Laurence Hurst reflects on the range of genome biological factors determining whether mutations have a selective effect, and how knowing more might help us to predict which will cause disease.
	49. 2886 Accesses	Review A review of fatty acid profiles and antioxidant content in grass-fed and grain-fed beef Cynthia A Daley, Amber Abbott, Patrick S Doyle, Glenn A Nader, Stephanie Larson Nutrition Journal 2010, 9:10 (10 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	50. 2891 Accesses	Research article A comparison of methods for differential expression analysis of RNA-seq data Charlotte Soneson, Mauro Delorenzi BMC Bioinformatics 2013, 14:91 (9 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	51. 2869 Accesses	Method Differential expression analysis for sequence count data Simon Anders, Wolfgang Huber Genome Biology 2010, 11:R106 (27 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| F1000 Biology \| Editor’s summary DEseq allows the determination of differential expression of read count data from RNA-seq or ChIP-seq experiments
	52. 2833 Accesses	Commentary The Hospital Anxiety And Depression Scale R Philip Snaith Health and Quality of Life Outcomes 2003, 1:29 (1 August 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	53. 2792 Accesses	Review A novel coronavirus capable of lethal human infections: an emerging picture Gulfaraz Khan Virology Journal 2013, 10:66 (28 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary This timely review summarises the ongoing outbreak of a novel coronavirus (HCoV-EMC), which has caused a number of fatal cases in the UK and Middle East.
	54. 2807 Accesses	Research article Amniotic fluid embolism incidence, risk factors and outcomes: a review and recommendations Marian Knight, Cynthia Berg, Peter Brocklehurst, Michael Kramer, Gwyneth Lewis, Jeremy Oats, Christine L Roberts, Catherine Spong, Elizabeth Sullivan, Jos van Roosmalen, Joost Zwart BMC Pregnancy and Childbirth 2012, 12:7 (10 February 2012) Abstract \| Full text \| PDF \| PubMed
	55. 2764 Accesses	Software Ultrafast and memory-efficient alignment of short DNA sequences to the human genome Ben Langmead, Cole Trapnell, Mihai Pop, Steven L Salzberg Genome Biology 2009, 10:R25 (4 March 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Bowtie: a new ultrafast memory-efficient tool for the alignment of short DNA sequence reads to large genomes.
	56. 2768 Accesses	Commentary International Society of Sports Nutrition position stand: creatine supplementation and exercise Thomas W Buford, Richard B Kreider, Jeffrey R Stout, Mike Greenwood, Bill Campbell, Marie Spano, Tim Ziegenfuss, Hector Lopez, Jamie Landis, Jose Antonio Journal of the International Society of Sports Nutrition 2007, 4:6 (30 August 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	57. 2751 Accesses	Research article Relationship between Organizational Culture, Leadership Behavior and Job Satisfaction Yafang Tsai BMC Health Services Research 2011, 11:98 (14 May 2011) Abstract \| Full text \| PDF \| PubMed
	58. 2722 Accesses	Commentary Processing of meats and cardiovascular risk: time to focus on preservatives Renata Micha, Georgios Michas, Martin Lajous, Dariush Mozaffarian BMC Medicine 2013, 11:136 (23 May 2013) Abstract \| Full text \| PDF \| PubMed \| 1 comment \| Editor’s summary Dariush Mozaffarian and colleagues comment on a study showing that processed meat is linked to increased mortality risk, and emphasize how health guidance should recommend avoiding processed meat rather than focusing on fat content.
	59. 2712 Accesses	Review Nutritional therapies for mental disorders Shaheen E Lakhan, Karen F Vieira Nutrition Journal 2008, 7:2 (21 January 2008) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	60. 2707 Accesses	Research article Depression, antidepressant medications, and risk of Clostridium difficile infection Mary A M Rogers, M Todd Greene, Vincent B Young, Sanjay Saint, Kenneth M Langa, John Y Kao, David M Aronoff BMC Medicine 2013, 11:121 (7 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The risk of Clostridium difficile infection is increased in adults with depression and in those taking antidepressants during hospitalization, indicating that physicians should be aware of the elevated infection risk in these patients.
	61. 2684 Accesses	Review Intestinal microbiota, probiotics and mental health: from Metchnikoff to modern advances: Part I – autointoxication revisited Alison C Bested, Alan C Logan, Eva M Selhub Gut Pathogens 2013, 5:5 (18 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	62. 2678 Accesses	Research Hookah smoking and cancer: carcinoembryonic antigen (CEA) levels in exclusive/ever hookah smokers Khan Sajid, Kamal Chaouachi, Rubaida Mahmood Harm Reduction Journal 2008, 5:19 (24 May 2008) Abstract \| Full text \| PDF \| PubMed \| 8 comments
	63. 2657 Accesses	Research Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe, Frank Speleman Genome Biology 2002, 3:research0034-research0034.11 (18 June 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Using real-time reverse transcription PCR ten housekeeping genes from different abundance and functional classes in various human tissues were evaluated. The conventional use of a single gene for normalization leads to relatively large errors in a significant proportion of samples tested.
	64. 2559 Accesses	Method Integrated analysis of recurrent properties of cancer genes to identify novel drivers Matteo D'Antonio, Francesca D Ciccarelli Genome Biology 2013, 14:R52 (29 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A method to detect rare driver genes through integrated analysis of expression profiles, mutation effects and properties of known cancer genes
	65. 2551 Accesses	Research Virophages, polintons, and transpovirons: a complex evolutionary network of diverse selfish genetic elements with different reproduction strategies Natalya Yutin, Didier Raoult, Eugene V Koonin Virology Journal 2013, 10:158 (23 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A phylogenomic analysis found that giant viruses, virophages and transposable elements have a complex evolutionary relationship, suggesting that viruses evolved from non-viral mobile genetic elements and vice versa, on more than one occasion.
	66. 2533 Accesses	Research Mutations within lncRNAs are effectively selected against in fruitfly but not in human Wilfried Haerty, Chris P Ponting Genome Biology 2013, 14:R49 (27 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Analysis of lncRNA conservation in fruitfly and humans shows that these elements are well conserved in insects, but not in mammals
	67. 2529 Accesses	Research Policymakers’ and other stakeholders’ perceptions of key considerations for health system decisions and the presentation of evidence to inform those considerations: an international survey Joshua P Vogel, Andrew D Oxman, Claire Glenton, Sarah Rosenbaum, Simon Lewin, A Gülmezoglu, João Souza Health Research Policy and Systems 2013, 11:19 (24 May 2013) Abstract \| Full text \| PDF \| PubMed
	68. 2522 Accesses	Research DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus Lucas JT Kaaij, Marc van de Wetering, Fang Fang, Benjamin Decato, Antoine Molaro, Harmen JG van de Werken, Johan H van Es, Jurian Schuijers, Elzo de Wit, Wouter de Laat, Gregory J Hannon, Hans C Clevers, Andrew D Smith, Rene F Ketting Genome Biology 2013, 14:R50 (28 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Intriguingly, DNA methylation in mouse intestinal cells does not change much during differentiation
	69. 2479 Accesses	Brief Report Diminished rostral anterior cingulate cortex activation during trauma-unrelated emotional interference in PTSD Reid Offringa, Kathryn Handwerger Brohawn, Lindsay K Staples, Stacey J Dubois, Katherine C Hughes, Danielle L Pfaff, Michael B VanElzakker, F Davis, Lisa M Shin Biology of Mood & Anxiety Disorders 2013, 3:10 (14 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	70. 2488 Accesses	Research article The weight of nations: an estimation of adult human biomass Sarah Walpole, David Prieto-Merino, Phil Edwards, John Cleland, Gretchen Stevens, Ian Roberts BMC Public Health 2012, 12:439 (18 June 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary National food energy requirements are primarily determined by the total biomass of the population rather than the population, suggesting that increasing body mass could have the same implications for world energy requirements as an extra 473 million people on earth.
	71. 2487 Accesses	Research No connection between the level of exposition to statins in the population and the incidence/mortality of acute myocardial infarction: An ecological study based on Sweden's municipalities Staffan Nilsson, Sigvard Mölstad, Catarina Karlberg, Jan-Erik Karlsson, Lars-Göran Persson Journal of Negative Results in BioMedicine 2011, 10:6 (24 May 2011) Abstract \| Full text \| PDF \| PubMed
	72. 2482 Accesses	Review Protein timing and its effects on muscular hypertrophy and strength in individuals engaged in weight-training Matthew Stark, Judith Lukaszuk, Aimee Prawitz, Amanda Salacinski Journal of the International Society of Sports Nutrition 2012, 9:54 (14 December 2012) Abstract \| Full text \| PDF \| PubMed
	73. 2480 Accesses	Research article Love thy neighbour: facilitation through an alternative signalling modality in plants Monica Gagliano, Michael Renton BMC Ecology 2013, 13:19 (7 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Chilli seedlings germinate better when grown in the presence of ‘good neighbour’ plants like basil even when all forms of chemical and visual signals are blocked, suggesting that an as-yet unidentified system of communication exists between plants.
	74. 2466 Accesses	Review Toxic epidermal necrolysis and Stevens-Johnson syndrome Thomas Harr, Lars E French Orphanet Journal of Rare Diseases 2010, 5:39 (16 December 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	75. 2455 Accesses	Letter Target blood pressure in sepsis: between a rock and a hard place Thiago Corrêa, Jukka Takala, Stephan Jakob Critical Care 2013, 17:433 (17 May 2013) Abstract \| Full text \| PDF \| PubMed
	76. 2443 Accesses	Research The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide Monica H Carlsen, Bente L Halvorsen, Kari Holte, Siv K Bøhn, Steinar Dragland, Laura Sampson, Carol Willey, Haruki Senoo, Yuko Umezono, Chiho Sanada, Ingrid Barikmo, Nega Berhe, Walter C Willett, Katherine M Phillips, David R Jacobs, Rune Blomhoff Nutrition Journal 2010, 9:3 (22 January 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	77. 2442 Accesses	Research article Clinical outcomes resulting from telemedicine interventions: a systematic review William R Hersh, Mark Helfand, James Wallace, Dale Kraemer, Patricia Patterson, Susan Shapiro, Merwyn Greenlick BMC Medical Informatics and Decision Making 2001, 1:5 (26 November 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Randomized controlled trials are needed, in all areas of health care, to determine the efficacy of telemedicine for clinical outcomes.
	78. 2443 Accesses	Meeting report Epigenetics and transgenerational inheritance Emilie Brasset, Séverine Chambeyron Genome Biology 2013, 14:306 (24 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A report on the 'Non-coding RNA, epigenetics and transgenerational inheritance' meeting, held at Churchill College, Cambridge, UK, April 11-12, 2013.
	79. 2449 Accesses	Research article Benchmarking short sequence mapping tools Ayat Hatem, Doruk Bozda¿, Amanda E Toland, Ümit V Çatalyürek BMC Bioinformatics 2013, 14:184 (7 June 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A benchmarking suite to analyze well-known next generation sequencing tools, mapping short reads to a reference genome, with respect to various technological and algorithmic perspectives and addressing issues using multiple approaches such as multiple simulators.
	80. 2436 Accesses	Review Beta-thalassemia Renzo Galanello, Raffaella Origa Orphanet Journal of Rare Diseases 2010, 5:11 (21 May 2010) Abstract \| Full text \| PDF \| PubMed
	81. 2417 Accesses	Methodology Therapeutic emails Farrokh Alemi, Mary R Haack, Susanna Nemes, Renita Aughburns, Jennifer Sinkule, Duncan Neuhauser Substance Abuse Treatment, Prevention, and Policy 2007, 2:7 (16 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	82. 2404 Accesses	Review Applications of nanoparticles in biology and medicine OV Salata Journal of Nanobiotechnology 2004, 2:3 (30 April 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	83. 2401 Accesses	Research article A phylogeny and revised classification of Squamata, including 4161 species of lizards and snakes R Pyron, Frank T Burbrink, John J Wiens BMC Evolutionary Biology 2013, 13:93 (29 April 2013) Abstract \| Full text \| PDF \| PubMed
	84. 2396 Accesses	Research The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage H Bradley Shaffer, Patrick Minx, Daniel E Warren, Andrew M Shedlock, Robert C Thomson, Nicole Valenzuela, John Abramyan, Chris T Amemiya, Daleen Badenhorst, Kyle K Biggar, Glen M Borchert, Christopher W Botka, Rachel M Bowden, Edward L Braun, Anne M Bronikowski, Benoit G Bruneau, Leslie T Buck, Blanche Capel, Todd A Castoe, Mike Czerwinski, Kim D Delehaunty, Scott V Edwards, Catrina C Fronick, Matthew K Fujita, Lucinda Fulton, Tina A Graves, Richard E Green, Wilfried Haerty, Ramkumar Hariharan, Omar Hernandez et al. Genome Biology 2013, 14:R28 (28 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The genome of the western painted turtle, Chrysemys picta bellii, reveals insights into its extreme tolerance to anoxia and freezing
	85. 2389 Accesses	Research Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group Rinaldo Bellomo, Claudio Ronco, John A Kellum, Ravindra L Mehta, Paul Palevsky, the ADQI workgroup Critical Care 2004, 8:R204-R212 (24 May 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| F1000
	86. 2386 Accesses	Research A survey of energy drink consumption patterns among college students Brenda M Malinauskas, Victor G Aeby, Reginald F Overton, Tracy Carpenter-Aeby, Kimberly Barber-Heidal Nutrition Journal 2007, 6:35 (31 October 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	87. 2350 Accesses	Research article Women with symptoms of uncomplicated urinary tract infection are often willing to delay antibiotic treatment: a prospective cohort study Bart J Knottnerus, Suzanne E Geerlings, Eric P van Charante, Gerben ter Riet BMC Family Practice 2013, 14:71 (31 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Over a third of women presenting with urinary tract infection symptoms are happy to delay antibiotic treatment when asked by their GP; the majority of these patients show an improvement in symptoms without further treatment
	88. 2341 Accesses	Research Characterizing the admixed African ancestry of African Americans Fouad Zakharia, Analabha Basu, Devin Absher, Themistocles L Assimes, Alan S Go, Mark A Hlatky, Carlos Iribarren, Joshua W Knowles, Jun Li, Balasubramanian Narasimhan, Steven Sidney, Audrey Southwick, Richard M Myers, Thomas Quertermous, Neil Risch, Hua Tang Genome Biology 2009, 10:R141 (22 December 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Genome-wide SNP analyses reveal the admixed African genetic ancestry of African Americans.
	89. 2316 Accesses	Opinion Thirty years on: HIV receptor gymnastics and the prevention of infection Robin A Weiss BMC Biology 2013, 11:57 (21 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Robin Weiss, in an article to mark the 30^th anniversary of the discovery of the human immunodeficiency virus (HIV), reviews the complex interactions of the virus with the specialized surface molecules by which it gains entry into cells, and how this has led to drugs that block it.
	90. 2301 Accesses	Commentary Why Do We Put Cervical Collars On Conscious Trauma Patients? Jonathan Benger, Julian Blackham Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2009, 17:44 (18 September 2009) Abstract \| Full text \| PDF \| PubMed
	91. 2301 Accesses	Commentary Body mass index and musculoskeletal pain: is there a connection? David R Seaman Chiropractic & Manual Therapies 2013, 21:15 (20 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary http://commons.wikimedia.org/wiki/File%3AOverweight_waistline.jpg
	92. 2293 Accesses	Study protocol Implementing the ten steps to successful breastfeeding in multiple hospitals serving low-wealth patients in the US: innovative research design and baseline findings Miriam H Labbok, Emily C Taylor, Nathan C Nickel International Breastfeeding Journal 2013, 8:5 (20 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	93. 2292 Accesses	Research Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing Shivendra Kishore, Andreas R Gruber, Dominik J Jedlinski, Afzal P Syed, Hadi Jorjani, Mihaela Zavolan Genome Biology 2013, 14:R45 (26 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary PAR-CLIP of snoRNA-associated proteins reveals the existence of extensive human loci that are processed into snoRNAs
	94. 2282 Accesses	Review Venous hemodynamics in neurological disorders: an analytical review with hydrodynamic analysis Clive B Beggs BMC Medicine 2013, 11:142 (31 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Neurological disorders, such as multiple sclerosis (MS) and leukoaraiosis have been associated with venous abnormalities that contribute to the pathophysiology; Clive Beggs reviews the evidence for this, concluding that the role of cerebral flow in MS remains unclear.
	95. 2275 Accesses	Review The Bhopal disaster and its aftermath: a review Edward Broughton Environmental Health: A Global Access Science Source 2005, 4:6 (10 May 2005) Abstract \| Full text \| PDF \| PubMed
	96. 2260 Accesses	Methodology article Statistical analysis of real-time PCR data Joshua S Yuan, Ann Reed, Feng Chen, C Neal Stewart BMC Bioinformatics 2006, 7:85 (22 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	97. 2264 Accesses	Interview In pursuit of an HIV vaccine: an interview with Andrew McMichael Andrew J McMichael BMC Biology 2013, 11:60 (21 May 2013) Full text \| PDF \| PubMed \| Editor’s summary Can the immune system be induced to protect itself against HIV infection? Andrew McMichael gives his perspective in an interview, explaining the challenges faced in making a vaccine and why he remains optimistic about the potential of eliciting strong T cell responses for controlling the virus.
	98. 2248 Accesses	Review Nutrition and cancer: A review of the evidence for an anti-cancer diet Michael S Donaldson Nutrition Journal 2004, 3:19 (20 October 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	99. 2242 Accesses	Method Quartz-Seq: a highly reproducible and sensitive single-cell RNA-Seq reveals non-genetic gene expression heterogeneity Yohei Sasagawa, Itoshi Nikaido, Tetsutaro Hayashi, Hiroki Danno, Kenichiro D Uno, Takeshi Imai, Hiroki R Ueda Genome Biology 2013, 14:R31 (17 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Quartz-Seq is a method for performing single cell RNA-seq which displays high reproducibility