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	51. 3198 Accesses	Research Hookah smoking and cancer: carcinoembryonic antigen (CEA) levels in exclusive/ever hookah smokers Khan Sajid, Kamal Chaouachi, Rubaida Mahmood Harm Reduction Journal 2008, 5:19 (24 May 2008) Abstract \| Full text \| PDF \| PubMed \| 8 comments
	52. 3189 Accesses	Software Ultrafast and memory-efficient alignment of short DNA sequences to the human genome Ben Langmead, Cole Trapnell, Mihai Pop, Steven L Salzberg Genome Biology 2009, 10:R25 (4 March 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Bowtie: a new ultrafast memory-efficient tool for the alignment of short DNA sequence reads to large genomes.
	53. 3162 Accesses	Commentary International Society of Sports Nutrition position stand: creatine supplementation and exercise Thomas W Buford, Richard B Kreider, Jeffrey R Stout, Mike Greenwood, Bill Campbell, Marie Spano, Tim Ziegenfuss, Hector Lopez, Jamie Landis, Jose Antonio Journal of the International Society of Sports Nutrition 2007, 4:6 (30 August 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	54. 3170 Accesses	Research CRISPR-Cas systems target a diverse collection of invasive mobile genetic elements in human microbiomes Quan Zhang, Mina Rho, Haixu Tang, Thomas G Doak, Yuzhen Ye Genome Biology 2013, 14:R40 (29 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Analysis of CRISPR sequences contained in human metagenomic datasets reveals a variety of different targeted mobile genetic elements
	55. 3161 Accesses	Correspondence A decadal view of biodiversity informatics: challenges and priorities Alex Hardisty, Dave Roberts, The Biodiversity Informatics Community BMC Ecology 2013, 13:16 (15 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Alex Hardisty and Dave Roberts outline a grand vision for the future of biodiversity research that is based on a fully integrated e-infrastructure, following a huge community consultation effort with the Biodiversity Informatics Community.
	56. 3150 Accesses	Review A novel coronavirus capable of lethal human infections: an emerging picture Gulfaraz Khan Virology Journal 2013, 10:66 (28 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary This timely review summarises the ongoing outbreak of a novel coronavirus (HCoV-EMC), which has caused a number of fatal cases in the UK and Middle East.
	57. 3134 Accesses	Review Apple phytochemicals and their health benefits Jeanelle Boyer, Rui Liu Nutrition Journal 2004, 3:5 (12 May 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	58. 3138 Accesses	Research Effect of fruit restriction on glycemic control in patients with type 2 diabetes – a randomized trial Allan S Christensen, Lone Viggers, Kjeld Hasselström, Søren Gregersen Nutrition Journal 2013, 12:29 (5 March 2013) Abstract \| Full text \| PDF \| PubMed
	59. 3133 Accesses	Debate Wikis, blogs and podcasts: a new generation of Web-based tools for virtual collaborative clinical practice and education Maged Boulos, Inocencio Maramba, Steve Wheeler BMC Medical Education 2006, 6:41 (15 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	60. 3133 Accesses	Study protocol Causes and consequences of cerebral small vessel disease. The RUN DMC study: a prospective cohort study. Study rationale and protocol Anouk GW van Norden, Karlijn F de Laat, Rob AR Gons, Inge WM van Uden, Ewoud J van Dijk, Lucas JB van Oudheusden, Rianne AJ Esselink, Bastiaan R Bloem, Baziel GM van Engelen, Machiel J Zwarts, Indira Tendolkar, Marcel G Olde-Rikkert, Maureen J van der Vlugt, Marcel P Zwiers, David G Norris, Frank-Erik de Leeuw BMC Neurology 2011, 11:29 (28 February 2011) Abstract \| Full text \| PDF \| PubMed
	61. 3134 Accesses	Research article Ancient origin of somatic and visceral neurons Marc Nomaksteinsky, Stefan Kassabov, Zoubida Chettouh, Henri-Corto Stoeklé, Laure Bonnaud, Gilles Fortin, Eric R Kandel, Jean-François Brunet BMC Biology 2013, 11:53 (30 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The great American palaeontologist and anatomist Alfred Romer speculated that early in animal life, an emerging somatic nervous system, focused on the outside world, struggled to dominate the visceral nervous system that takes care of the internal systems that keep us alive. Jean-François Brunet and colleagues identify the molecular signatures that tell the evolutionary tale of this duality.
	62. 3130 Accesses	Review The Bhopal disaster and its aftermath: a review Edward Broughton Environmental Health: A Global Access Science Source 2005, 4:6 (10 May 2005) Abstract \| Full text \| PDF \| PubMed
	63. 3132 Accesses	Method Differential expression analysis for sequence count data Simon Anders, Wolfgang Huber Genome Biology 2010, 11:R106 (27 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| F1000 Biology \| Editor’s summary DEseq allows the determination of differential expression of read count data from RNA-seq or ChIP-seq experiments
	64. 3122 Accesses	Review Nutritional therapies for mental disorders Shaheen E Lakhan, Karen F Vieira Nutrition Journal 2008, 7:2 (21 January 2008) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	65. 3108 Accesses	Methodology Stool substitute transplant therapy for the eradication of Clostridium difficile infection: ‘RePOOPulating’ the gut Elaine O Petrof, Gregory B Gloor, Stephen J Vanner, Scott J Weese, David Carter, Michelle C Daigneault, Eric M Brown, Kathleen Schroeter, Emma Allen-Vercoe Microbiome 2013, 1:3 (9 January 2013) Abstract \| Full text \| PDF \| Editor’s summary A super-probiotic synthetic stool, composed of 33 different bacterial strains, was developed and used to treat two patients with severe C. difficile infection. The probiotic bacteria could still be detected up to six months after inoculation.
	66. 3074 Accesses	Review A review of fatty acid profiles and antioxidant content in grass-fed and grain-fed beef Cynthia A Daley, Amber Abbott, Patrick S Doyle, Glenn A Nader, Stephanie Larson Nutrition Journal 2010, 9:10 (10 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	67. 3008 Accesses	Review Applications of nanoparticles in biology and medicine OV Salata Journal of Nanobiotechnology 2004, 2:3 (30 April 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	68. 3000 Accesses	Research article Relationship between Organizational Culture, Leadership Behavior and Job Satisfaction Yafang Tsai BMC Health Services Research 2011, 11:98 (14 May 2011) Abstract \| Full text \| PDF \| PubMed
	69. 2986 Accesses	Review Fructose, insulin resistance, and metabolic dyslipidemia Heather Basciano, Lisa Federico, Khosrow Adeli Nutrition & Metabolism 2005, 2:5 (21 February 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	70. 2952 Accesses	Research A human Dravet syndrome model from patient induced pluripotent stem cells Norimichi Higurashi, Taku Uchida, Christoph Lossin, Yoshio Misumi, Yohei Okada, Wado Akamatsu, Yoichi Imaizumi, Bo Zhang, Kazuki Nabeshima, Masayuki X Mori, Shutaro Katsurabayashi, Yukiyoshi Shirasaka, Hideyuki Okano, Shinichi Hirose Molecular Brain 2013, 6:19 (2 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Induced pluripotent stem cells from the skin of patients with Dravet syndrome show Dravet-like functional impairment when they are converted into neurons, providing an unparalleled insight into the mechanism behind this rare form of infantile-onset epilepsy.
	71. 2934 Accesses	Research Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe, Frank Speleman Genome Biology 2002, 3:research0034-research0034.11 (18 June 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Using real-time reverse transcription PCR ten housekeeping genes from different abundance and functional classes in various human tissues were evaluated. The conventional use of a single gene for normalization leads to relatively large errors in a significant proportion of samples tested.
	72. 2933 Accesses	Research Continuous on-line glucose measurement by microdialysis in a central vein. A pilot study Christina Blixt, Olav Rooyackers, Bengt Isaksson, Jan Wernerman Critical Care 2013, 17:R87 (11 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A potential new tool for intravascular continuous glucose monitoring in intensive care patients could prevent hypoglycaemia or high glucose variability.
	73. 2902 Accesses	Commentary It is time to rethink tactics in the fight against malaria Laurence Slutsker, S Kachur Malaria Journal 2013, 12:140 (24 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary On world malaria day, renowned malariologists from CDC discuss dangers and resilience, despite successful control in many areas, and how we may need to rethink our strategy in order to defeat the parasite.
	74. 2874 Accesses	Review The Quality of Life Scale (QOLS): Reliability, Validity, and Utilization Carol S Burckhardt, Kathryn L Anderson Health and Quality of Life Outcomes 2003, 1:60 (23 October 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	75. 2873 Accesses	Research How to interpret the transmissibility of novel influenza A(H7N9): an analysis of initial epidemiological data of human cases from China Hiroshi Nishiura, Kenji Mizumoto, Keisuke Ejima Theoretical Biology and Medical Modelling 2013, 10:30 (4 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	76. 2862 Accesses	Research Motor recovery monitoring using acceleration measurements in post acute stroke patients Jayavardhana Gubbi, Aravinda S. Rao, Kun Fang, Bernard Yan, Marimuthu Palaniswami BioMedical Engineering OnLine 2013, 12:33 (16 April 2013) Abstract \| Provisional PDF \| PubMed
	77. 2823 Accesses	Research Noninvasive ventilation immediately after extubation improves weaning outcome after acute respiratory failure: a randomized controlled trial Susana R Ornico, Suzana M Lobo, Helder S Sanches, Maristela Deberaldini, Luciane T Tófoli, Ana M Vidal, Guilherme P Schettino, Marcelo B Amato, Carlos R Carvalho, Carmen S Barbas Critical Care 2013, 17:R39 (4 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A randomized controlled trial shows that non-invasive ventilation applied immediately after extubation prevents re-intubation and decreases hospital mortality when compared to oxygen mask therapy.
	78. 2822 Accesses	Research Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group Rinaldo Bellomo, Claudio Ronco, John A Kellum, Ravindra L Mehta, Paul Palevsky, the ADQI workgroup Critical Care 2004, 8:R204-R212 (24 May 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| F1000
	79. 2827 Accesses	Method jMOSAiCS: joint analysis of multiple ChIP-seq datasets Xin Zeng, Rajendran Sanalkumar, Emery H Bresnick, Hongda Li, Qiang Chang, Sunduz Keles Genome Biology 2013, 14:R38 (29 April 2013) Abstract \| Provisional PDF \| Editor’s summary A novel probabilistic method for jointly analyzing multiple ChIP-seq datasets offers an improvement over chromHMM
	80. 2812 Accesses	Review Clinical review: Does it matter which hemodynamic monitoring system is used? Davinder Ramsingh, Brenton Alexander, Maxime Cannesson Critical Care 2012, 17:208 (5 March 2013) Abstract \| Full text \| PDF
	81. 2787 Accesses	Research The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide Monica H Carlsen, Bente L Halvorsen, Kari Holte, Siv K Bøhn, Steinar Dragland, Laura Sampson, Carol Willey, Haruki Senoo, Yuko Umezono, Chiho Sanada, Ingrid Barikmo, Nega Berhe, Walter C Willett, Katherine M Phillips, David R Jacobs, Rune Blomhoff Nutrition Journal 2010, 9:3 (22 January 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	82. 2770 Accesses	Research Improvement in coronary heart disease risk factors during an intermittent fasting/calorie restriction regimen: Relationship to adipokine modulations Cynthia M Kroeger, Monica C Klempel, Surabhi Bhutani, John F Trepanowski, Christine C Tangney, Krista A Varady Nutrition & Metabolism 2012, 9:98 (31 October 2012) Abstract \| Full text \| PDF \| PubMed
	83. 2742 Accesses	Research Sex & vision I: Spatio-temporal resolution Israel Abramov, James Gordon, Olga Feldman, Alla Chavarga Biology of Sex Differences 2012, 3:20 (4 September 2012) Abstract \| Full text \| PDF \| PubMed
	84. 2741 Accesses	Case Report Torsion of ovarian cyst during pregnancy: a case report Vasavi Kolluru, Rekha Gurumurthy, Venkatasujatha Vellanki, Deshpande Gururaj Cases Journal 2009, 2:9405 (31 December 2009) Abstract \| Full text \| PDF \| PubMed
	85. 2690 Accesses	Research Systematic biases in DNA copy number originate from isolation procedures Sebastiaan van Heesch, Michal Mokry, Veronika Boskova, Wade Junker, Rajdeep Mehon, Pim Toonen, Ewart de Bruijn, James D Shull, Timothy J Aitman, Edwin Cuppen, Victor Guryev Genome Biology 2013, 14:R33 (24 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A new study pinpoints the sources of copy number variation biases, highlighting the important issue of sample preparation
	86. 2673 Accesses	Research Long-term effects of low-fat diets either low or high in protein on cardiovascular and metabolic risk factors: a systematic review and meta-analysis Lukas Schwingshackl, Georg Hoffmann Nutrition Journal 2013, 12:48 (15 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	87. 2673 Accesses	Research The health impacts of globalisation: a conceptual framework Maud MTE Huynen, Pim Martens, Henk BM Hilderink Globalization and Health 2005, 1:14 (3 August 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	88. 2666 Accesses	Research article Effect of an electronic nicotine delivery device (e-Cigarette) on smoking reduction and cessation: a prospective 6-month pilot study Riccardo Polosa, Pasquale Caponnetto, Jaymin B Morjaria, Gabriella Papale, Davide Campagna, Cristina Russo BMC Public Health 2011, 11:786 (11 October 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	89. 2655 Accesses	Review Weight Science: Evaluating the Evidence for a Paradigm Shift Linda Bacon, Lucy Aphramor Nutrition Journal 2011, 10:9 (24 January 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	90. 2650 Accesses	Research article Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium Fabienne Meier-Abt, Emanuela Milani, Tim Roloff, Heike Brinkhaus, Stephan Duss, Dominique S Meyer, Ina Klebba, Piotr J Balwierz, Erik van Nimwegen, Mohamed Bentires-Alj Breast Cancer Research 2013, 15:R36 (29 April 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Early parity in mice alters the genomic signature of a distinct subset of mammary epithelial cells by inducing differentiation and reducing proliferation, ultimately protecting against breast cancer.
	91. 2616 Accesses	Research article Effects of supplemental fish oil on resting metabolic rate, body composition, and salivary cortisol in healthy adults Eric E Noreen, Michael J Sass, Megan L Crowe, Vanessa A Pabon, Josef Brandauer, Lindsay K Averill Journal of the International Society of Sports Nutrition 2010, 7:31 (8 October 2010) Abstract \| Full text \| PDF \| PubMed
	92. 2597 Accesses	Review Nutrition and cancer: A review of the evidence for an anti-cancer diet Michael S Donaldson Nutrition Journal 2004, 3:19 (20 October 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	93. 2591 Accesses	Research Volumetric three-dimensional intravascular ultrasound visualization using shape-based nonlinear interpolation Yonghoon Rim, David D McPherson, Hyunggun Kim BioMedical Engineering OnLine 2013, 12:39 (7 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	94. 2587 Accesses	Commentary Somatic and visceral nervous systems - an ancient duality Paola Bertucci, Detlev Arendt BMC Biology 2013, 11:54 (30 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The idea that vertebrates are composed of a ‘visceral’ and ‘somatic’ self, responding to internal and external stimuli, respectively, was first put forward in the 19th century. Now, molecular fingerprinting indicates a duality between the somatic and visceral nervous systems that appears to predate Bilataria.
	95. 2580 Accesses	Review Toxic epidermal necrolysis and Stevens-Johnson syndrome Thomas Harr, Lars E French Orphanet Journal of Rare Diseases 2010, 5:39 (16 December 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	96. 2576 Accesses	Research Consumption of low-fat dairy foods for 6 months improves insulin resistance without adversely affecting lipids or bodyweight in healthy adults: a randomized free-living cross-over study Todd C Rideout, Christopher P F Marinangeli, Heather Martin, Richard W Browne, Curtis B Rempel Nutrition Journal 2013, 12:56 (2 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	97. 2560 Accesses	Research Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing Jason O'Rawe, Tao Jiang, Guangqing Sun, Yiyang Wu, Wei Wang, Jingchu Hu, Paul Bodily, Lifeng Tian, Hakon Hakonarson, W Evan Johnson, Zhi Wei, Kai Wang, Gholson J Lyon Genome Medicine 2013, 5:28 (27 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Head-to-head comparison of widely used variant calling pipelines including SOAP, GATK and Complete Genomics using default parameters reveals discrepancies between the pipelines.
	98. 2543 Accesses	Research Renaissance of base deficit for the initial assessment of trauma patients: a base deficit-based classification for hypovolemic shock developed on data from 16,305 patients derived from the TraumaRegister DGU^® Manuel Mutschler, Ulrike Nienaber, Thomas Brockamp, Arasch Wafaisade, Tobias Fabian, Thomas Paffrath, Bertil Bouillon, Marc Maegele, the TraumaRegister DGU Critical Care 2013, 17:R42 (6 March 2013) Abstract \| Full text \| PDF \| PubMed \| 1 comment \| Editor’s summary Base deficit (BD)-based shock classification better discriminates the need for early blood transfusion and mortality in severely injured patients than the current Advanced Trauma Life Support (ATLS) protocol.
	99. 2526 Accesses	Research article Ubiquinol supplementation enhances peak power production in trained athletes: a double-blind, placebo controlled study Dietmar Alf, Michael E Schmidt, Stefan C Siebrecht Journal of the International Society of Sports Nutrition 2013, 10:24 (29 April 2013) Abstract \| Full text \| PDF \| PubMed