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26.

4587
Accesses

Research article   Open Access

Does long-term creatine supplementation impair kidney function in resistance-trained individuals consuming a high-protein diet?

Rebeca Lugaresi, Marco Leme, Vítor de Salles Painelli, Igor Murai, Hamilton Roschel, Marcelo Sapienza, Antonio Lancha Junior, Bruno Gualano Journal of the International Society of Sports Nutrition 2013, 10:26 (16 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

More evidence to show that creatine is safe.

27.

4520
Accesses

Review   Open Access Highly Accessed

Ketogenic diets and physical performance

Stephen D Phinney Nutrition & Metabolism 2004, 1:2 (17 August 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

28.

4468
Accesses

Research   Open Access Highly Accessed

The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage

John Abramyan, Daleen Badenhorst, Kyle K Biggar, Glen M Borchert, Christopher W Botka, Rachel M Bowden, Edward L Braun, Anne M Bronikowski, Benoit G Bruneau, Leslie T Buck, Blanche Capel, Todd A Castoe, Mike Czerwinski, Kim D Delehaunty, Scott V Edwards, Catrina C Fronick, Matthew K Fujita, Lucinda Fulton, Tina A Graves, Richard E Green, Wilfried Haerty, Ramkumar Hariharan, LaDeana H Hillier, Alisha K Holloway, Daniel Janes, Fredric J Janzen, Cyriac Kandoth, Lesheng Kong, Jason de Koning, Yang Li et al. Genome Biology 2013, 14:R28 (28 March 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

The genome of the western painted turtle, Chrysemys picta bellii, reveals insights into its extreme tolerance to anoxia and freezing

29.

4354
Accesses

Research   Open Access Highly Accessed

Prenatal and perinatal analgesic exposure and autism: an ecological link

Ann Z Bauer, David Kriebel Environmental Health 2013, 12:41 (9 May 2013)

Abstract | Provisional PDF | PubMed

30.

4271
Accesses

Research   Open Access Highly Accessed

Nuclear war between Israel and Iran: lethality beyond the pale

Cham E Dallas, William C Bell, David J Stewart, Antonio Caruso, Frederick M Burkle, Jr Conflict and Health 2013, 7:10 (10 May 2013)

Abstract | Provisional PDF | PubMed

31.

4189
Accesses

Method   Open Access Highly Accessed

Quartz-Seq: a highly reproducible and sensitive single-cell RNA-Seq reveals non-genetic gene expression heterogeneity

Yohei Sasagawa, Itoshi Nikaido, Tetsutaro Hayashi, Hiroki Danno, Kenichiro D Uno, Takeshi Imai, Hiroki R Ueda Genome Biology 2013, 14:R31 (17 April 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

Quartz-Seq is a method for performing single cell RNA-seq which displays high reproducibility

32.

3973
Accesses

Research   Open Access Highly Accessed

Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels

Yanning Zheng, Qiang Liu, Lingling Li, Wen Qin, Jianming Yang, Haibo Zhang, Xinglin Jiang, Tao Cheng, Wei Liu, Xin Xu, Mo Xian Biotechnology for Biofuels 2013, 6:57 (24 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

33.

3991
Accesses

Research   Open Access

The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice

Marguerite Prior, Richard Dargusch, Jennifer L Ehren, Chandramouli Chiruta, David Schubert Alzheimer's Research & Therapy 2013, 5:25 (14 May 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

Novel drug candidate J147 is able to arrest and reverse memory deficits and improve several aspects of brain function in aged mice with advanced symptoms of Alzheimer's disease (AD).

34.

3888
Accesses

Review   Open Access Highly Accessed

ISSN exercise & sport nutrition review: research & recommendations

Richard B Kreider, Colin D Wilborn, Lem Taylor, Bill Campbell, Anthony L Almada, Rick Collins, Mathew Cooke, Conrad P Earnest, Mike Greenwood, Douglas S Kalman, Chad M Kerksick, Susan M Kleiner, Brian Leutholtz, Hector Lopez, Lonnie M Lowery, Ron Mendel, Abbie Smith, Marie Spano, Robert Wildman, Darryn S Willoughby, Tim N Ziegenfuss, Jose Antonio Journal of the International Society of Sports Nutrition 2010, 7:7 (2 February 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

35.

3883
Accesses

Research   Open Access Highly Accessed

The burden of non communicable diseases in developing countries

Abdesslam Boutayeb, Saber Boutayeb International Journal for Equity in Health 2005, 4:2 (14 January 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

36.

3702
Accesses

Research   Open Access

Slower immune system aging in women versus men in the Japanese population

Katsuiku Hirokawa, Masanori Utsuyama, Yoshio Hayashi, Masanobu Kitagawa, Takashi Makinodan, Tamas Fulop Immunity & Ageing 2013, 10:19 (15 May 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The female's immune system declines at a slower rate than the male's during ageing, contributing (in part) to the significantly longer life expectancy found in women, compared to men.

37.

3638
Accesses

Research article   Open Access Highly Accessed

Amniotic fluid embolism incidence, risk factors and outcomes: a review and recommendations

Marian Knight, Cynthia Berg, Peter Brocklehurst, Michael Kramer, Gwyneth Lewis, Jeremy Oats, Christine L Roberts, Catherine Spong, Elizabeth Sullivan, Jos van Roosmalen, Joost Zwart BMC Pregnancy and Childbirth 2012, 12:7 (10 February 2012)

Abstract | Full text | PDF | PubMed

38.

3496
Accesses

Review   Open Access Highly Accessed

Critical care management of severe traumatic brain injury in adults

Samir H Haddad, Yaseen M Arabi Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012, 20:12 (3 February 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

39.

3483
Accesses

Research article   Open Access Highly Accessed

A comparison of methods for differential expression analysis of RNA-seq data

Charlotte Soneson, Mauro Delorenzi BMC Bioinformatics 2013, 14:91 (9 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

40.

3460
Accesses

Research   Open Access Highly Accessed

Body weight status and cardiovascular risk factors in adults by frequency of candy consumption

Mary M Murphy, Leila M Barraj, Xiaoyu Bi, Nicolas Stettler Nutrition Journal 2013, 12:53 (30 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

41.

3445
Accesses

Correspondence   Open Access Highly Accessed

Mistaken Identifiers: Gene name errors can be introduced inadvertently when using Excel in bioinformatics

Barry R Zeeberg, Joseph Riss, David W Kane, Kimberly J Bussey, Edward Uchio, W Marston Linehan, J Carl Barrett, John N Weinstein BMC Bioinformatics 2004, 5:80 (23 June 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 7 comments

42.

3436
Accesses

Commentary   Open Access Highly Accessed

International Society of Sports Nutrition position stand: protein and exercise

Bill Campbell, Richard B Kreider, Tim Ziegenfuss, Paul La Bounty, Mike Roberts, Darren Burke, Jamie Landis, Hector Lopez, Jose Antonio Journal of the International Society of Sports Nutrition 2007, 4:8 (26 September 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

43.

3424
Accesses

Research   Open Access Highly Accessed

A survey of energy drink consumption patterns among college students

Brenda M Malinauskas, Victor G Aeby, Reginald F Overton, Tracy Carpenter-Aeby, Kimberly Barber-Heidal Nutrition Journal 2007, 6:35 (31 October 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

44.

3414
Accesses

Commentary   Open Access Highly Accessed

The Hospital Anxiety And Depression Scale

R Philip Snaith Health and Quality of Life Outcomes 2003, 1:29 (1 August 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

45.

3397
Accesses

Research   Open Access Highly Accessed

CRISPR-Cas systems target a diverse collection of invasive mobile genetic elements in human microbiomes

Quan Zhang, Mina Rho, Haixu Tang, Thomas G Doak, Yuzhen Ye Genome Biology 2013, 14:R40 (29 April 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

Analysis of CRISPR sequences contained in human metagenomic datasets reveals a variety of different targeted mobile genetic elements

46.

3383
Accesses

Technical advance   Open Access Highly Accessed

A new growth chart for preterm babies: Babson and Benda's chart updated with recent data and a new format

Tanis R Fenton BMC Pediatrics 2003, 3:13 (16 December 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

47.

3299
Accesses

Review   Open Access Highly Accessed

A novel coronavirus capable of lethal human infections: an emerging picture

Gulfaraz Khan Virology Journal 2013, 10:66 (28 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This timely review summarises the ongoing outbreak of a novel coronavirus (HCoV-EMC), which has caused a number of fatal cases in the UK and Middle East.

48.

3192
Accesses

Research article   Open Access Highly Accessed

Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women

Hector L Lopez, Tim N Ziegenfuss, Jennifer E Hofheins, Scott M Habowski, Shawn M Arent, Joseph P Weir, Arny A Ferrando Journal of the International Society of Sports Nutrition 2013, 10:22 (19 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

49.

3247
Accesses

Research   Open Access Highly Accessed

Detection of the valvular split within the second heart sound using the reassigned smoothed pseudo Wigner-Ville distribution

Abdelghani Djebbari, Fethi Bereksi-Reguig BioMedical Engineering OnLine 2013, 12:37 (30 April 2013)

Abstract | Provisional PDF | PubMed

50.

3246
Accesses

Research article   Open Access Highly Accessed

Ancient origin of somatic and visceral neurons

Marc Nomaksteinsky, Stefan Kassabov, Zoubida Chettouh, Henri-Corto Stoeklé, Laure Bonnaud, Gilles Fortin, Eric R Kandel, Jean-François Brunet BMC Biology 2013, 11:53 (30 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The great American palaeontologist and anatomist Alfred Romer speculated that early in animal life, an emerging somatic nervous system, focused on the outside world, struggled to dominate the visceral nervous system that takes care of the internal systems that keep us alive. Jean-François Brunet and colleagues identify the molecular signatures that tell the evolutionary tale of this duality.

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