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Study protocols of trials in the Tailored Implementation for Chronic Diseases (TICD) project

An article collection published in Trials.

The Tailored Implementation for Chronic Diseases project is a project funded by the European Community under its Framework 7 program. This collection of articles describes the study protocols of five cluster randomized trials in different countries and targeting different chronic conditions. It also includes the study protocol of a process evaluation in these five trials.

  1. Study protocol

    Evaluation of a tailored implementation strategy to improve the management of patients with chronic obstructive pulmonary disease in primary care: a study protocol of a cluster randomized trial

    Chronic obstructive pulmonary disease (COPD) remains a major health problem, strongly related to smoking. Despite the publication of practice guidelines on prevention and treatment, not all patients with the d...

    Maciek Godycki-Cwirko, Izabela Zakowska, Katarzyna Kosiek, Michel Wensing, Jaroslaw Krawczyk and Anna Kowalczyk

    Trials 2014 15:109

    Published on: 4 April 2014

  2. Methodology

    Tailored Implementation for Chronic Diseases (TICD): a protocol for process evaluation in cluster randomized controlled trials in five European countries

    In the ‘Tailored Implementation for Chronic Diseases (TICD)’ project, five tailored implementation programs to improve healthcare delivery in different chronic conditions have been developed. These programs wi...

    Cornelia Jäger, Tobias Freund, Jost Steinhäuser, Eivind Aakhus, Signe Flottorp, Maciek Godycki-Cwirko, Jan van Lieshout, Jane Krause, Joachim Szecsenyi and Michel Wensing

    Trials 2014 15:87

    Published on: 21 March 2014

  3. Study protocol

    Evaluation of a tailored intervention to improve management of overweight and obesity in primary care: study protocol of a cluster randomised controlled trial

    In the UK around 22% of men and 24% of women are obese, and there are varying but worrying levels in other European countries. Obesity is a chronic condition that carries an important health risk. National gui...

    Jane Krause, Shona Agarwal, Danielle H Bodicoat, Arne Ring, David Shepherd, Stephen Rogers, Michel Wensing and Richard Baker

    Trials 2014 15:82

    Published on: 19 March 2014

  4. Study protocol

    Tailored interventions to implement recommendations for elderly patients with depression in primary care: a study protocol for a pragmatic cluster randomised controlled trial

    The prevalence of depression is high and the elderly have an increased risk of developing chronic course. International data suggest that depression in the elderly is under-recognised, the latency before clini...

    Eivind Aakhus, Ingeborg Granlund, Jan Odgaard-Jensen, Michel Wensing, Andrew D Oxman and Signe A Flottorp

    Trials 2014 15:16

    Published on: 9 January 2014

  5. Study protocol

    Effectiveness of a tailored intervention to improve cardiovascular risk management in primary care: study protocol for a randomised controlled trial

    Cardiovascular disease (CVD) is an important worldwide cause of mortality. In The Netherlands, CVD is the leading cause of death for women and the second cause of death for men. Recommendations for diagnosis a...

    Elke Huntink, Naomi Heijmans, Michel Wensing and Jan van Lieshout

    Trials 2013 14:433

    Published on: 17 December 2013

  6. Study protocol

    A tailored implementation intervention to implement recommendations addressing polypharmacy in multimorbid patients: study protocol of a cluster randomized controlled trial

    Multimorbid patients frequently receive complex medication regimens and are at higher risk for adverse drug reactions and hospitalisations. Managing patients with polypharmacy is demanding, because it requires...

    Cornelia Jäger, Tobias Freund, Jost Steinhäuser, Stefanie Joos, Michel Wensing and Joachim Szecsenyi

    Trials 2013 14:420

    Published on: 5 December 2013

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