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Post-Traumatic Stress Disorder (PTSD): Biopsychosocial Translational Research and Everyday Practice

Edited by: Prof. Alexander V. Libin

Posttraumatic Stress Disorder (PTSD) is a complex of trauma triggered mental health conditions caused by experiencing intolerable amount of stress. The emotional and social-behavioral changes following PTSD are acknowledged to be among the most devastating consequences of traumatic experience and are strongly associated with problems in daily functioning and an unfavorable social outcome. PTSD diagnosis in both military and civilian populations is highly correlated with behavioral symptoms such as social dysfunction across multiple domains on community integration, including loss of important relationships, disrupted family life, poor work-related quality of life, and reduced individual activity.

PTSD is often complicated by multiple neurologic co-morbidities and functional disabilities such as those caused by Traumatic Brain Injury (TBI)/Polytrauma, and further convoluted by substance abuse, suicidal ideation, chronic depression and anxiety, and fragile social supports.

Studies emphasize the dramatic impact of PTSD and associated complex medical conditions among both active duty troops, as well as difficulties that such impairments present for returning service members. There is mounting evidence to suggest that executive dysfunction and emotional dysregulation resulting from a CNS insult causes both short-term and long-term consequences causing poor goal-directed behavior, impaired decision making, and significant decrease in independent functioning. Timely detection of the disabling impact of PTSD on human activities is necessary for both the accurate diagnosis and individual-tailoring of rehabilitation processes aimed at recovery of independent function.

In this thematic series, we would like to demonstrate how medical and rehabilitation research translates through best practices in interventional psychosocial rehabilitation, physical and psychological health interface, and assessment of relevant outcomes to the ultimate goal of clinical practice: facilitation of successful social reintegration of fractured by trauma individuals.

  1. Research

    Revascularization and outcomes in Veterans with moderate to severe ischemia on myocardial perfusion imaging

    The prevalence of ischemia on nuclear myocardial perfusion imaging (MPI) has been decreasing. Recent research has questioned the benefit of invasive revascularization for patients with moderate to severe ische...

    David E. Winchester, Alexander J. Bolanos, Anita Wokhlu, Rebecca J. Beyth and Leslee J. Shaw

    Military Medical Research 2017 4:12

    Published on: 1 April 2017

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