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The LCNTDR Collection: Advances in scientific research for NTD control

The London Centre for Neglected Tropical Disease Research (LCNTDR) is an innovative research collaboration, bringing together leading experts to tackle diseases which affect the lives of over 1.7 billion of the poorest people across the globe.

LCNTDR undertakes cutting-edge research to build the evidence base around the design, implementation and evaluation of neglected tropical disease prevention, control, elimination and eradication programmes.

LCNTDR was launched in 2013 with the aim of providing focused operational and research support for NTD control. LCNTDR member institutions house world renowned NTD experts with a wide range of specialties, making the Centre a valuable resource for cross-sectoral research and collaboration. The founding members of the LCNTDR are the Royal Veterinary CollegeImperial College London, the London School of Hygiene & Tropical Medicine and the Natural History Museum.

From 2021, LCNTDR has been expanding its membership base, welcoming institutions engaged in NTD research based either in London or in countries where NTDs are endemic. New London based institutional members include St George’s University of London, London School of Economics and Politics, University of Greenwich, University of Surrey, Kingston University, UKNEQAS and UCL Hospital for Tropical Diseases.  International members include Ethiopian Public Health Institute, University of Papua New Guinea, C. K. Tedam University of Technology and Applied Sciences (Ghana) and Kwame Nkrumah University of Science and Technology (Ghana).

LCNTDR is committed to addressing the priorities outlined in Ending the neglected to attain the Sustainable Development Goals: A road map for neglected tropical diseases 2021-2030, as reflected in our Mission and Objectives. LCNTDR recognises the huge progress made in combatting NTDs since its inception, but also that a commitment to research and innovation is needed to achieve and sustain 2030 road map targets.


View all collections published in Parasites & Vectors


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  1. Soil-transmitted helminths (STH) are still highly prevalent in southeast Asia. The country of Myanmar has had ongoing mass drug administration (MDA) programmes since 2003 in an attempt to control STH and reduc...

    Authors: Julia C. Dunn, Alison A. Bettis, Nay Yee Wyine, Aye Moe Moe Lwin, Soe Thiha Lwin, Khine Khine Su, Myint Myint Sein, Aung Tun, Nay Soe Maung and Roy M. Anderson
    Citation: Parasites & Vectors 2017 10:374
  2. There is an increased focus on whether mass drug administration (MDA) programmes alone can interrupt the transmission of soil-transmitted helminths (STH). Mathematical models can be used to model these interve...

    Authors: James E. Truscott, Marleen Werkman, James E. Wright, Sam H. Farrell, Rajiv Sarkar, Kristjana Ásbjörnsdóttir and Roy M. Anderson
    Citation: Parasites & Vectors 2017 10:321
  3. There is currently no vaccine available to protect humans against infection with the schistosome digenean parasites, although candidate formulations for Schistosoma mansoni are under trial in animal models, inclu...

    Authors: Andria Stylianou, Christoforos Hadjichrysanthou, James E. Truscott and Roy M. Anderson
    Citation: Parasites & Vectors 2017 10:294
  4. Systematic non-compliance to chemotherapeutic treatment among a portion of the eligible population is thought to be a major obstacle to the elimination of helminth infections by mass drug administration (MDA)....

    Authors: Sam H. Farrell, James E. Truscott and Roy M. Anderson
    Citation: Parasites & Vectors 2017 10:291
  5. Understanding and quantifying the sources and implications of error in the measurement of helminth egg intensity using Kato-Katz (KK) and the newly emerging “gold standard” quantitative polymerase chain reacti...

    Authors: Alice V. Easton, Rita G. Oliveira, Martin Walker, Elise M. O’Connell, Sammy M. Njenga, Charles S. Mwandawiro, Joanne P. Webster, Thomas B. Nutman and Roy M. Anderson
    Citation: Parasites & Vectors 2017 10:256
  6. Current WHO guidelines for soil-transmitted helminth (STH) control focus on mass drug administration (MDA) targeting preschool-aged (pre-SAC) and school-aged children (SAC), with the goal of eliminating STH as...

    Authors: Marleen Werkman, James E. Truscott, Jaspreet Toor, James E. Wright and Roy M. Anderson
    Citation: Parasites & Vectors 2017 10:254
  7. The majority of schistosomiasis control programmes focus on targeting school-aged children. Expanding the use of community-wide mass treatment to reach more adults is under consideration. However, it should be...

    Authors: Hugo C. Turner, James E. Truscott, Alison A. Bettis, Sam H. Farrell, Arminder K. Deol, Jane M. Whitton, Fiona M. Fleming and Roy M. Anderson
    Citation: Parasites & Vectors 2017 10:213
  8. The filarial nematodes Wuchereria bancrofti (Cobbold, 1877), Brugia malayi (Brug, 1927) and B. timori Partono, Purnomo, Dennis, Atmosoedjono, Oemijati & Cross, 1977 cause lymphatic diseases in humans in the tropi...

    Authors: Shigehiko Uni, Ahmad Syihan Mat Udin, Takeshi Agatsuma, Weerachai Saijuntha, Kerstin Junker, Rosli Ramli, Hasmahzaiti Omar, Yvonne Ai-Lian Lim, Sinnadurai Sivanandam, Emilie Lefoulon, Coralie Martin, Daicus Martin Belabut, Saharul Kasim, Muhammad Rasul Abdullah Halim, Nur Afiqah Zainuri, Subha Bhassu…
    Citation: Parasites & Vectors 2017 10:194
  9. Ocular Chlamydia trachomatis (Ct) infection causes trachoma, the leading infectious cause of blindness. A Ct D/UW3 proteome microarray and sera from Gambian adults with trachomatous trichiasis (TT) or healthy mat...

    Authors: Harry Pickering, Sarah E. Burr, Tamsyn Derrick, Pateh Makalo, Hassan Joof, Richard D. Hayward and Martin J. Holland
    Citation: Parasites & Vectors 2017 10:143
  10. A method is outlined for the use of an individual-based stochastic model of parasite transmission dynamics to assess different designs for a cluster randomized trial in which mass drug administration (MDA) is ...

    Authors: Roy Anderson, Sam Farrell, Hugo Turner, Judd Walson, Christl A. Donnelly and James Truscott
    Citation: Parasites & Vectors 2017 10:93
  11. Globally, in 2010, approximately 1.5 billion people were infected with at least one species of soil-transmitted helminth (STH), Ascaris lumbricoides, Trichuris trichiura, hookworm (Ancylostoma duodenale and Necat...

    Authors: William E. Oswald, Aisha E. P. Stewart, Michael R. Kramer, Tekola Endeshaw, Mulat Zerihun, Berhanu Melak, Eshetu Sata, Demelash Gessese, Tesfaye Teferi, Zerihun Tadesse, Birhan Guadie, Jonathan D. King, Paul M. Emerson, Elizabeth K. Callahan, Matthew C. Freeman, W. Dana Flanders…
    Citation: Parasites & Vectors 2017 10:91
  12. The pork tapeworm, Taenia solium, and associated human infections, taeniasis, cysticercosis and neurocysticercosis, are serious public health problems, especially in developing countries. The World Health Organiz...

    Authors: Peter Winskill, Wendy E. Harrison, Michael D. French, Matthew A. Dixon, Bernadette Abela-Ridder and María-Gloria Basáñez
    Citation: Parasites & Vectors 2017 10:73
  13. Elimination of urogenital schistosomiasis transmission is a priority for the Zanzibar Ministry of Health. Preventative chemotherapy together with additional control interventions have successfully alleviated m...

    Authors: Tom Pennance, Bobbie Person, Mtumweni Ali Muhsin, Alipo Naim Khamis, Juma Muhsin, Iddi Simba Khamis, Khalfan Abdallah Mohammed, Fatma Kabole, David Rollinson and Stefanie Knopp
    Citation: Parasites & Vectors 2016 9:646
  14. Understanding whether schistosomiasis control programmes are on course to control morbidity and potentially switch towards elimination interventions would benefit from user-friendly quantitative tools that fac...

    Authors: Arminder Deol, Joanne P. Webster, Martin Walker, Maria-Gloria Basáñez, T. Déirdre Hollingsworth, Fiona M. Fleming, Antonio Montresor and Michael D. French
    Citation: Parasites & Vectors 2016 9:543
  15. Vector-biting behaviour is important for vector-borne disease (VBD) epidemiology. The proportion of blood meals taken on humans (the human blood index, HBI), is a component of the biting rate per vector on hum...

    Authors: Poppy H. L. Lamberton, Robert A. Cheke, Martin Walker, Peter Winskill, J. Lee Crainey, Daniel A. Boakye, Mike Y. Osei-Atweneboana, Iñaki Tirados, Michael D. Wilson, Anthony Tetteh-Kumah, Sampson Otoo, Rory J. Post and María-Gloria Basañez
    Citation: Parasites & Vectors 2016 9:432
  16. Trusted literate, or semi-literate, community drug distributors (CDDs) are the primary implementers in integrated preventive chemotherapy (IPC) programmes for Neglected Tropical Disease (NTD) control. The CDDs...

    Authors: Fiona M. Fleming, Fred Matovu, Kristian S. Hansen and Joanne P. Webster
    Citation: Parasites & Vectors 2016 9:345
  17. The African Programme for Onchocerciasis Control has proposed provisional thresholds for the prevalence of microfilariae in humans and of L3 larvae in blackflies, below which mass drug administration (MDA) wit...

    Authors: Christian Bottomley, Valerie Isham, Sarai Vivas-Martínez, Annette C. Kuesel, Simon K. Attah, Nicholas O. Opoku, Sara Lustigman, Martin Walker and Maria-Gloria Basáñez
    Citation: Parasites & Vectors 2016 9:343
  18. Brucella melitensis causes production losses in ruminants and febrile disease in humans in Africa, Central Asia, the Middle East and elsewhere. Although traditionally understood to aff...

    Authors: Wendy Beauvais, Imadidden Musallam and Javier Guitian
    Citation: Parasites & Vectors 2016 9:55
  19. Animal African trypanosomiasis (AAT) is one of the biggest constraints to livestock production and a threat to food security in sub-Saharan Africa. In order to optimise the allocation of resources for AAT cont...

    Authors: H. R. Holt, R. Selby, C. Mumba, G. B. Napier and J. Guitian
    Citation: Parasites & Vectors 2016 9:53
  20. Schistosomiasis affects more than 800 million people, mostly in sub-Saharan Africa. A baseline sentinel site study was conducted in the Western half of Madagascar to determine the prevalence and intensity of s...

    Authors: Clara Fabienne Rasoamanamihaja, Alain Marcel Rahetilahy, Bruno Ranjatoarivony, Neerav Dhanani, Luciano Andriamaro, Samuel Hermas Andrianarisoa and Peter Mark Jourdan
    Citation: Parasites & Vectors 2016 9:50
  21. The clinical outcomes associated with Chagas disease remain poorly understood. In addition to the burden of morbidity, the burden of mortality due to Trypanosoma cruzi infection can be substantial, yet its quanti...

    Authors: Zulma M. Cucunubá, Omolade Okuwoga, María-Gloria Basáñez and Pierre Nouvellet
    Citation: Parasites & Vectors 2016 9:42
  22. By 2020, the global health community aims to control and eliminate human helminthiases, including schistosomiasis in selected African countries, principally by preventive chemotherapy (PCT) through mass drug a...

    Authors: Martin Walker, Tarub S. Mabud, Piero L. Olliaro, Jean T. Coulibaly, Charles H. King, Giovanna Raso, Alexandra U. Scherrer, J. Russell Stothard, José Carlos Sousa-Figueiredo, Katarina Stete, Jürg Utzinger and Maria-Gloria Basáñez
    Citation: Parasites & Vectors 2016 9:41
  23. The World Health Organization (WHO) has set goals for onchocerciasis elimination in Latin America by 2015. Most of the six previously endemic countries are attaining this goal by implementing twice a year (and...

    Authors: Carlos Botto, María-Gloria Basañez, Marisela Escalona, Néstor J. Villamizar, Oscar Noya-Alarcón, José Cortez, Sarai Vivas-Martínez, Pablo Coronel, Hortencia Frontado, Jorge Flores, Beatriz Graterol, Oneida Camacho, Yseliam Tovar, Daniel Borges, Alba Lucia Morales, Dalila Ríos…
    Citation: Parasites & Vectors 2016 9:40
  24. Soil-transmitted helminth (STH) infections of humans fall within the World Health Organization’s (WHO) grouping termed the neglected tropical diseases (NTDs). It is estimated that they affect approximately 1.4...

    Authors: Julia C. Dunn, Hugo C. Turner, Aung Tun and Roy M. Anderson
    Citation: Parasites & Vectors 2016 9:31
  25. Preventive chemotherapy (PCT) programmes are used to control five of the highest burden neglected tropical diseases (NTDs): soil-transmitted helminth infections (hookworm, ascariasis, and trichuriasis), lympha...

    Authors: Kathryn V. Shuford, Hugo C. Turner and Roy M. Anderson
    Citation: Parasites & Vectors 2016 9:29
  26. Visceral Leishmaniasis (VL) is a neglected vector-borne disease. In India, it is transmitted to humans by Leishmania donovani-infected Phlebotomus argentipes sand flies. In 2005, VL was targeted for elimination b...

    Authors: Mary M. Cameron, Alvaro Acosta-Serrano, Caryn Bern, Marleen Boelaert, Margriet den Boer, Sakib Burza, Lloyd A. C. Chapman, Alexandra Chaskopoulou, Michael Coleman, Orin Courtenay, Simon Croft, Pradeep Das, Erin Dilger, Geraldine Foster, Rajesh Garlapati, Lee Haines…
    Citation: Parasites & Vectors 2016 9:25