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A new combination of fipronil and permethrin for the control of ectoparasites of dogs

This article collection is a series of seven papers describing studies on the efficacy of a new combination of fipronil and permethrin in a spot-on formulation for dogs (Frontline Tri-Act®/Frontect®, Merial).

The ectoparasites of dogs, including ticks and several types of insects, represent a nuisance and can cause direct damage to their hosts, which may also comprise people and other animals. Due to the potential transmission of pathogenic bacteria, protozoa, helminths and viruses, many of which are zoonotic, ectoparasites of dogs additionally represent an indirect threat to both veterinary medicine and public health.

The new fipronil and permethrin ectoparasiticide combination provides a high and long lasting efficacy against ticks, fleas, mosquitoes, sand flies and stable flies, following a single topical application on dogs. This new combination protects dogs from the direct actions of ectoparasites and will also prevent infection with vector-borne agents that cause canine diseases and might affect humans and other hosts as well.

This article collection page was created to facilitate access to research articles published in Parasites & Vectors relating to this topic. The article processing charges for the Research articles in the collection have been funded by Merial and a detailed conflict of interest statement is included within each article. The Guest Editor coordinated the peer-review of each manuscript following the journal’s peer review policy. The Guest Editor declares he does not have any conflicts of interest. Each article can also be found individually in the journal.

Edited by: Dr Luis Cardosa
Collection published: 27 January 2015

View all collections published in Parasites & Vectors

  1. Research

    Knock-down and speed of kill of a combination of fipronil and permethrin for the prevention of Ctenocephalides felis flea infestation in dogs

    A topical combination of fipronil + permethrin (Frontline Tri-Act®/Frontect®, Merial) has recently been developed to control fleas, ticks, mosquitoes, sandflies and stable flies on dogs. Two studies were condu...

    Lénaïg Halos, Josephus J. Fourie, Becky Fankhauser and Frederic Beugnet

    Parasites & Vectors 2016 9:57

    Published on: 2 February 2016

  2. Research

    Repellency and acaricidal efficacy of a new combination of fipronil and permethrin against Ixodes ricinus and Rhipicephalus sanguineus ticks on dogs

    A blinded, controlled laboratory study was conducted to assess the repellency and acaricidal activity of a topical spot on formulation, a combination of fipronil and permethrin, against Ixodes ricinus and Rhipice...

    Pascal Dumont, Julian Liebenberg, Frederic Beugnet and Becky Fankhauser

    Parasites & Vectors 2015 8:531

    Published on: 13 October 2015

  3. Research

    Efficacy of a new combination of fipronil and permethrin against Ctenocephalides felis flea infestation in dogs

    Five studies were conducted to evaluate the effect of a new combination of fipronil and permethrin on cat fleas, Ctenocephalides felis, when applied to dogs, including dogs that underwent water exposure or shampo...

    Becky Fankhauser, Pascal Dumont, Lénaïg Halos, James S Hunter III, Bruce Kunkle, William R Everett, Theodore S Chester, Josephus J Fourie and Mark D Soll

    Parasites & Vectors 2015 8:62

    Published on: 29 January 2015

  4. Research

    Repellency, prevention of attachment and acaricidal efficacy of a new combination of fipronil and permethrin against the main vector of canine babesiosis in Europe, Dermacentor reticulatus ticks

    Dermacentor reticulatus is a European hard tick of major veterinary importance because it is the vector of canine babesiosis due to Babesia canis. The efficacy against this particular tick spec...

    Pascal Dumont, Josephus J Fourie, Mark Soll and Frédéric Beugnet

    Parasites & Vectors 2015 8:50

    Published on: 27 January 2015

  5. Research

    Repellent and insecticidal efficacy of a new combination of fipronil and permethrin against the main vector of canine leishmaniosis in Europe (Phlebotomus perniciosus)

    Two successive laboratory experiments (A and B) were conducted to confirm the efficacy of a new fipronil and permethrin combination to repel and kill Phlebotomus perniciosus sandflies when applied once topically ...

    Pascal Dumont, Becky Fankhauser, Emilie Bouhsira, Emmanuel Lienard, Philippe Jacquiet, Frederic Beugnet and Michel Franc

    Parasites & Vectors 2015 8:49

    Published on: 27 January 2015

  6. Research

    Acaricidal efficacy of a new combination of fipronil and permethrin against Ixodes ricinus and Rhipicephalus sanguineus ticks

    Two blinded, controlled laboratory studies were conducted to assess the acaricidal efficacy of a new combination of fipronil and permethrin (Frontline Tri-Act®/Frontect®) against two tick species. Study A eval...

    Pascal Dumont, Theodore S Chester, Boyd Gale, Mark Soll, Josephus J Fourie and Frédéric Beugnet

    Parasites & Vectors 2015 8:51

    Published on: 27 January 2015

  7. Research

    Repellent and insecticidal efficacy of a new combination of fipronil and permethrin against stable flies (Stomoxys calcitrans)

    A laboratory study was conducted to assess the repellent and insecticidal efficacy of a new combination of fipronil and permethrin (Frontline Tri- Act®/Frontect® Merial) against Stomoxys calcitrans (stable flies)

    Becky Fankhauser, Jennifer P Irwin, Morgan L Stone, S Theodore Chester and Mark D Soll

    Parasites & Vectors 2015 8:61

    Published on: 26 January 2015

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