Recent advances, such as single-cell sequencing technologies and new algorithmic methods, are allowing us to study cancer genomics at a depth and breadth that was not previously possible.
Genome Biology highlights the importance of this field with a special collection covering all aspects of cancer progression and heterogeneity, including methodological advances to study cancer evolution and clonality, insights into tumor heterogeneity, discussions on personalized genomics and ethics of cancer data sharing, and more.