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Ebola outbreaks and community-based surveillance response systems

Edited by: George F Gao, Dr. Ernest Tambo, Prof. Xiao-Nong Zhou

Establishment of effective surveillance and response strategies are recognized globally as the pillars for tackling the outbreaks of infectious diseases as well as elimination and eradication of diseases. Thus surveillance response activities do not only require preparedness, planning and efficient coordination and management of resources in research and development of tools, such as Ebola vaccines and treatments, but importantly also increasing community awareness, mobilization and participation for further development of the response structure to stem out Ebola epidemic.

Ebola virus disease (EVD) is a disease of humans and other primates caused by ebolaviruses with a death rate of EV infected cases around 50% to 90% varied in different outbreaks since 1976. Its incubation period or the time between exposure to the virus and the development of symptoms of the disease is between 2 to 21 days leading to chronic hemorrhages and multiple organs failure, yet no effective treatment and Ebola vaccine is available. Ebola outbreak in West Africa has shown the gaps in the national and global surveillance response and knowledge translations, which resulting to preventable 4,922 deaths toll out of 10,141 cases of EVD in West Africa alone by 25 October, 2014. The challenge with EVD reside in its early detection with daily similar trickery symptoms with malaria, cholera and other viral hemorrhagic fevers, etc., and rapid healthcare emergency and crisis responses management, contact tracing, collaboration, solidarity and effective communication with community.

Thus, the thematic series on the topic of “Ebola outbreaks and community-based surveillance response systems” offer unique opportunity to present the human-animal interplay knowledge and information gaps, ethical and legal challenges, community-based EVD strategies and translational research priorities. In particularly, community-based establishment of EVD epidemic surveillance response systems will trig more stakeholders to work on evidence-based research against EVD outbreaks or pandemics and provide the decision-making policy support systems, viable interventions and responses in local settings and global scenarios as well.

  1. Research Article

    Clinical presentations and outcomes of patients with Ebola virus disease in Freetown, Sierra Leone

    Clinical and laboratory data were collected and analysed from patients with Ebola virus disease (EVD) in Jui Government Hospital in Freetown, Sierra Leone, where patients with EVD were received and/or treated ...

    Ying-Jie Ji, Xue-Zhang Duan, Xu-Dong Gao, Lei Li, Chen Li, Dong Ji, Wen-Gang Li, Li-Fu Wang, Yu-Hua Meng, Xiao Yang, Bin-Fang Ling, Xue-Ai Song, Mei-Lei Gu, Tao Jiang, She-Ku M. Koroma, James Bangalie…

    Infectious Diseases of Poverty 2016 5:101

    Published on: 3 November 2016

  2. Research article

    Virtual screening of the inhibitors targeting at the viral protein 40 of Ebola virus

    The Ebola virus is highly pathogenic and destructive to humans and other primates. The Ebola virus encodes viral protein 40 (VP40), which is highly expressed and regulates the assembly and release of viral par...

    V. Karthick, N. Nagasundaram, C. George Priya Doss, Chiranjib Chakraborty, R. Siva, Aiping Lu, Ge Zhang and Hailong Zhu

    Infectious Diseases of Poverty 2016 5:12

    Published on: 17 February 2016

  3. Research Article

    Assessment of the usefulness of integrated disease surveillance and response on suspected ebola cases in the Brong Ahafo Region, Ghana

    This study assessed the quality, core and support functions of the integrated disease surveillance and response (IDSR) system relating to 18 suspected cases of Ebola virus disease (EVD) in the Brong Ahafo Regi...

    Kofi Issah, Kennedy Nartey, Richard Amoah, Emmanuel George Bachan, Jacob Aleeba, Enuamah Yeetey and Timothy Letsa

    Infectious Diseases of Poverty 2015 4:17

    Published on: 10 April 2015

  4. Scoping Review

    Ebola, the killer virus

    Ebola virus disease (EVD) has mostly affected economically deprived countries as limited resources adversely affect a country’s infrastructure and administration. Probing into the factors that led to the wides...

    Haider Ghazanfar, Fizza Orooj, Muhammad Ahmed Abdullah and Ali Ghazanfar

    Infectious Diseases of Poverty 2015 4:15

    Published on: 8 April 2015

  5. Opinion

    Ebola wreaks havoc in Sierra Leone

    Ebola virus disease has taken a toll on more than 8,000 lives in West Africa in 2014. The most affected countries are Guinea, Liberia, and Sierra Leone. The number of people infected by Ebola in Sierra Leone s...

    Mohamed Koroma and Shan Lv

    Infectious Diseases of Poverty 2015 4:10

    Published on: 26 January 2015

  6. Letter to the Editor

    Are surveillance response systems enough to effectively combat and contain the Ebola outbreak?

    The epidemic of the Ebola virus infection in West Africa in 2014 has become a worldwide concern. Due to the nature of the disease, which has an extremely high mortality potential, this outbreak has received mu...

    Viroj Wiwanitkit, Ernest Tambo, Emmanuel Chidiebere Ugwu, Jeane Yonkeu Ngogang and Xiao-Nong Zhou

    Infectious Diseases of Poverty 2015 4:7

    Published on: 9 January 2015

  7. Opinion

    Human Ebola virus infection in West Africa: a review of available therapeutic agents that target different steps of the life cycle of Ebola virus

    The recent outbreak of the human Zaire ebolavirus (EBOV) epidemic is spiraling out of control in West Africa. Human EBOV hemorrhagic fever has a case fatality rate of up to 90%. The EBOV is classified as a bio...

    Kang Yiu Lai, Wing Yiu George Ng and Fan Fanny Cheng

    Infectious Diseases of Poverty 2014 3:43

    Published on: 28 November 2014

  8. Editorial

    Acquired immunity and asymptomatic reservoir impact on frontline and airport ebola outbreak syndromic surveillance and response

    The number of surveillance networks for infectious disease diagnosis and response has been growing. In 2000, the World Health Organization (WHO) established the Global Outbreak Alert and Response Network, whic...

    Ernest Tambo and Zhou Xiao-Nong

    Infectious Diseases of Poverty 2014 3:41

    Published on: 29 October 2014

    The Erratum to this article has been published in Infectious Diseases of Poverty 2015 4:16

  9. Letter to the Editor

    Need of surveillance response systems to combat Ebola outbreaks and other emerging infectious diseases in African countries

    There is growing concern in Sub-Saharan Africa about the spread of the Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, and the public health burden that it ensues. Since 1976, there have...

    Ernest Tambo, Emmanuel Chidiebere Ugwu and Jeane Yonkeu Ngogang

    Infectious Diseases of Poverty 2014 3:29

    Published on: 5 August 2014

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