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H3K4 trimethylation is strongly associated with active transcription. The deposition of this mark is catalyzed by SET-domain methyltransferases, which consist of a subcomplex containing WDR5, ASH2L, and RBBP5 ...
The original article was published in BMC Nursing 2016 15:9
The aims of this study were i) to evaluate mitral and aortic annuli excursion, and aortomitral angle (AMA) during the cardiac cycle in healthy adults using two-dimensional speckle tracking echocardiography, ii...
Previous studies have demonstrated an association between DNA methylation-based measures of accelerated ageing and age-related health outcomes and mortality. As a disease closely associated with advancing age,...
Recent studies now provide a relatively robust explanation of how moral behavior evolved, perhaps not just in humans. An analysis of current biology textbooks shows that they fail to address this critical topi...
In several canine models of hereditary human disease the homozygote dogs die prior to puberty, or have substantially reduced fertility. To create a clinically healthy animal that can be bred, but can also tran...
This article is part of a Supplement: Volume 19 Supplement 1
This is the second in a series of three articles documenting the geographical distribution of 41 dominant vector species (DVS) of human malaria. The first paper addressed the DVS of the Americas and the third ...
This article is part of a Supplement: Volume 11 Supplement 2
This article is part of a Supplement: Volume 11 Supplement 2
This article is part of a Supplement: Volume 11 Supplement 2
In March 2009, the Task Force for Innovative International Financing for Health Systems recommended "a health systems funding platform for the Global Fund, GAVI Alliance, the World Bank and others to coordinat...
This is a review of recent publications and journal articles about evolution and paleontology.
There is no doubt that cancer is not only a genetic disease but that it can also occur due to epigenetic abnormalities. Diet and environmental factors can alter the scope of epigenetic regulation. The results ...
This article is part of a Supplement: Volume 18 Supplement 1
The editors of BMC Medical Ethics would like to thank all our reviewers who have contributed to the journal in Volume 16 (2015).
The 2007 global economic recession was the most severe recession since the Great Depression of the 1930s in terms of declines in unemployment, labor force participation and gross domestic product in the United...
Ethnic differences in non-communicable disease risk have been described between individuals of South Asian and European ethnicity that are only partially explained by genetics and other known risk factors. DNA...
Previously, we reported effects of the cry b mutation on circadian rhythms in period and timeless gene expression within isolated peripheral Drosophila tissues. We relied on...
A report on the Cold Spring Harbor Laboratory Mechanisms of Eukaryotic Transcription meeting, Cold Spring Harbor, New York, USA, August 27–31, 2013.