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25 result(s) for 'author#Wilfried Haerty' within BMC
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Citation: BMC Genomics 2022 23:79
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The tech for the next decade: promises and challenges in genome biology
The 19th Annual Advances in Genome Biology and Technology (AGBT) meeting came back to Marco Island, Florida, and was held in the renovated venue from 27 February to 2 March 2019. The meeting showed a variety o...
Citation: Genome Biology 2019 20:86 -
Molecular evidence for increased regulatory conservation during metamorphosis, and against deleterious cascading effects of hybrid breakdown in Drosophila
Speculation regarding the importance of changes in gene regulation in determining major phylogenetic patterns continues to accrue, despite a lack of broad-scale comparative studies examining how patterns of ge...
Citation: BMC Biology 2010 8:26 -
Mutations within lncRNAs are effectively selected against in fruitfly but not in human
Previous studies in Drosophila and mammals have revealed levels of long non-coding RNAs (lncRNAs) sequence conservation that are intermediate between neutrally evolving and protein-coding sequence. These analyses...
Citation: Genome Biology 2013 14:R49 -
The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage
We describe the genome of the western painted turtle, Chrysemys picta bellii, one of the most widespread, abundant, and well-studied turtles. We place the genome into a comparative evolutionary context, and focus...
Citation: Genome Biology 2013 14:R28 -
Analysis of structural variants in four African cichlids highlights an association with developmental and immune related genes
East African lake cichlids are one of the most impressive examples of an adaptive radiation. Independently in Lake Victoria, Tanganyika, and Malawi, several hundreds of species arose within the last 10 million...
Citation: BMC Evolutionary Biology 2020 20:69 -
Roadblock: improved annotations do not necessarily translate into new functional insights
Citation: Genome Biology 2021 22:320 -
Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes
Alternative splicing is a key mechanism underlying cellular differentiation and a driver of complexity in mammalian neuronal tissues. However, understanding of which isoforms are differentially used or express...
Citation: BMC Genomics 2022 23:42 -
Evolution of regulatory networks associated with traits under selection in cichlids
Seminal studies of vertebrate protein evolution speculated that gene regulatory changes can drive anatomical innovations. However, very little is known about gene regulatory network (GRN) evolution associated ...
Citation: Genome Biology 2021 22:25 -
A rather dry subject; investigating the study of arid-associated microbial communities
Almost one third of Earth’s land surface is arid, with deserts alone covering more than 46 million square kilometres. Nearly 2.1 billion people inhabit deserts or drylands and these regions are also home to a ...
Citation: Environmental Microbiome 2020 15:20 -
Comparative analysis of function and interaction of transcription factors in nematodes: Extensive conservation of orthology coupled to rapid sequence evolution
Much of the morphological diversity in eukaryotes results from differential regulation of gene expression in which transcription factors (TFs) play a central role. The nematode Caenorhabditis elegans is an establ...
Citation: BMC Genomics 2008 9:399 -
Identification of functional long non-coding RNAs in C. elegans
Functional characterisation of the compact genome of the model organism Caenorhabditis elegans remains incomplete despite its sequencing 20 years ago. The last decade of research has seen a tremendous increase in...
Citation: BMC Biology 2019 17:14 -
Chromosome-level genome sequence of the Genetically Improved Farmed Tilapia (GIFT, Oreochromis niloticus) highlights regions of introgression with O. mossambicus
The Nile tilapia (Oreochromis niloticus) is the third most important freshwater fish for aquaculture. Its success is directly linked to continuous breeding efforts focusing on production traits such as growth rat...
Citation: BMC Genomics 2022 23:832 -
Ontogeny and phylogeny: molecular signatures of selection, constraint, and temporal pleiotropy in the development of Drosophila
Karl Ernst Von Baer noted that species tend to show greater morphological divergence in later stages of development when compared to earlier stages. Darwin originally interpreted these observations via a selec...
Citation: BMC Biology 2009 7:42 -
Identification of molecular signatures specific for distinct cranial sensory ganglia in the developing chick
The cranial sensory ganglia represent populations of neurons with distinct functions, or sensory modalities. The production of individual ganglia from distinct neurogenic placodes with different developmental ...
Citation: Neural Development 2016 11:3 -
Genome sequencing of the staple food crop white Guinea yam enables the development of a molecular marker for sex determination
Root and tuber crops are a major food source in tropical Africa. Among these crops are several species in the monocotyledonous genus Dioscorea collectively known as yam, a staple tuber crop that contributes enorm...
Citation: BMC Biology 2017 15:86 -
Validation of a novel associative transcriptomics pipeline in Brassica oleracea: identifying candidates for vernalisation response
Associative transcriptomics has been used extensively in Brassica napus to enable the rapid identification of markers correlated with traits of interest. However, within the important vegetable crop species, Bras...
Citation: BMC Genomics 2021 22:539 -
Dominant integration locus drives continuous diversification of plant immune receptors with exogenous domain fusions
The plant immune system is innate and encoded in the germline. Using it efficiently, plants are capable of recognizing a diverse range of rapidly evolving pathogens. A recently described phenomenon shows that ...
Citation: Genome Biology 2018 19:23 -
Third chromosome candidate genes for conspecific sperm precedence between D. simulans and D. mauritiana
Male - female incompatibilities can be critical in keeping species as separate and discrete units. Premating incompatibilities and postzygotic hybrid sterility/inviability have been widely studied as isolating...
Citation: BMC Genetics 2010 11:21 -
microRNA profiling in the Weddell seal suggests novel regulatory mechanisms contributing to diving adaptation
The Weddell Seal (Leptonychotes weddelli) represents a remarkable example of adaptation to diving among marine mammals. This species is capable of diving > 900 m deep and remaining underwater for more than 60 min...
Citation: BMC Genomics 2020 21:303