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10 result(s) for 'author#Wai Hoong Chang' within BMC

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  1. Tumor prostheses currently give the best short- and medium-term results for limb-salvage reconstruction procedures in the treatment of bone tumors. However, in developing countries, the cost of a tumor prosthe...

    Authors: Kok Long Pan, Wai Hoong Chan, Gek Bee Ong, Shanmugam Premsenthil, Mohammad Zulkarnaen, Dayangku Norlida and Zainal Abidin
    Citation: World Journal of Surgical Oncology 2012 10:105
    Content type: Research Published on:

  2. Since its discovery almost three decades ago, the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway has paved the road for understanding inflammatory and immunity processes rel...

    Authors: Wai Hoong Chang and Alvina G. Lai
    Citation: Molecular Medicine 2019 25:46
    Content type: Research article Published on:

  3. People with liver disease are at increased risk of developing cardiovascular disease (CVD), however, there has yet been an investigation of incidence burden, risk, and premature mortality across a wide range o...

    Authors: Wai Hoong Chang, Stefanie H. Mueller, Sheng-Chia Chung, Graham R. Foster and Alvina G. Lai
    Citation: Journal of Translational Medicine 2022 20:2
    Content type: Research Published on:

  4. The objective of this study was to employ ensemble clustering and tree-based risk model approaches to identify interactions between clinicogenomic features for colorectal cancer using the 100,000 Genomes Project.

    Authors: Yuguo Wei, Nikolaos Papachristou, Stefanie Mueller, Wai Hoong Chang and Alvina G. Lai
    Citation: BMC Research Notes 2021 14:385
    Content type: Research note Published on:

  5. An Informatics Consult has been proposed in which clinicians request novel evidence from large scale health data resources, tailored to the treatment of a specific patient. However, the availability of such co...

    Authors: Alvina G. Lai, Wai Hoong Chang, Constantinos A. Parisinos, Michail Katsoulis, Ruth M. Blackburn, Anoop D. Shah, Vincent Nguyen, Spiros Denaxas, George Davey Smith, Tom R. Gaunt, Krishnarajah Nirantharakumar, Murray P. Cox, Donall Forde, Folkert W. Asselbergs, Steve Harris, Sylvia Richardson…
    Citation: BMC Medical Informatics and Decision Making 2021 21:281
    Content type: Research article Published on:

  6. The AMP-activated protein kinase (AMPK) is an evolutionarily conserved regulator of cellular energy homeostasis. As a nexus for transducing metabolic signals, AMPK cooperates with other energy-sensing pathways...

    Authors: Wai Hoong Chang and Alvina G. Lai
    Citation: BMC Cancer 2020 20:773
    Content type: Research article Published on:

  7. Tumor hypoxia is associated with metastasis and resistance to chemotherapy and radiotherapy. Genes involved in oxygen-sensing are clinically relevant and have significant implications for prognosis. In this st...

    Authors: Wai Hoong Chang, Donall Forde and Alvina G. Lai
    Citation: Cancer Communications 2019 39:23
    Content type: Original article Published on:

  8. Despite much progress in cancer research, its incidence and mortality continue to rise. A robust biomarker that would predict tumor behavior is highly desirable and could improve patient treatment and prognosis.

    Authors: Wai Hoong Chang, Donall Forde and Alvina G. Lai
    Citation: Journal of Translational Medicine 2019 17:14
    Content type: Research Published on:

  9. The circadian clock governs a large variety of fundamentally important physiological processes in all three domains of life. Consequently, asynchrony in timekeeping mechanisms could give rise to cellular dysfu...

    Authors: Wai Hoong Chang and Alvina G. Lai
    Citation: Journal of Translational Medicine 2019 17:132
    Content type: Research Published on: