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14 result(s) for 'author#Sébastien Perreault' within BMC
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Citation: Clinical Proteomics 2009 5(Suppl 1):9035
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A phase 2 study of trametinib for patients with pediatric glioma or plexiform neurofibroma with refractory tumor and activation of the MAPK/ERK pathway: TRAM-01
Pediatric low-grade gliomas (PLGG) are the most frequent brain tumors in children. Up to 50% will be refractory to conventional chemotherapy. It is now known that the majority of PLGG have activation of the MA...
Citation: BMC Cancer 2019 19:1250 -
Thank you to Virology Journal’s peer reviewers in 2014
The editors of Virology Journal would like to thank all our reviewers who have contributed to the journal in Volume 11 (2014). The success of any scientific journal depends on an effective and strict peer review ...
Citation: Virology Journal 2015 12:65 -
ERK-associated changes in E2F4 phosphorylation, localization and transcriptional activity during mitogenic stimulation in human intestinal epithelial crypt cells
The transcription factor E2F4 controls proliferation of normal and cancerous intestinal epithelial cells. E2F4 localization in normal human intestinal epithelial cells (HIEC) is cell cycle-dependent, being cyt...
Citation: BMC Cell Biology 2013 14:33 -
Effect of thermal therapy and exercises on acute low back pain: a protocol for a randomized controlled trial
Low back pain (LBP) is the first cause of years lived with disability worldwide. This is due to the development of chronic pain. Thus, it is necessary to identify the best therapeutic approaches in the acute p...
Citation: BMC Musculoskeletal Disorders 2020 21:814 -
The association between waiting time and multidisciplinary pain treatment outcomes in patients with rheumatic conditions
Access to multidisciplinary pain treatment facilities (MPTF) is limited by extensive waiting time in many countries. However, there is a lack of knowledge about the impact of waiting time on clinical outcomes,...
Citation: BMC Rheumatology 2020 4:59 -
Steady-state visual evoked potentials in children with neurofibromatosis type 1: associations with behavioral rating scales and impact of psychostimulant medication
Neurofibromatosis type 1 (NF1) is a genetic disorder often associated with cognitive dysfunctions, including a high occurrence of deficits in visuoperceptual skills. The neural underpinnings of these visuoperc...
Citation: Journal of Neurodevelopmental Disorders 2022 14:42 -
Preliminary assessment of the performance of oyster shells and chitin materials as adsorbents in the removal of saxitoxin in aqueous solutions
This study evaluated the adsorption capacity of the natural materials chitin and oyster shell powder (OSP) in the removal of saxitoxin (STX) from water. Simplified reactors of adsorption were prepared containi...
Citation: Chemistry Central Journal 2012 6:86 -
Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues
Endogenous retroelements (EREs) constitute about 42% of the human genome and have been implicated in common human diseases such as autoimmunity and cancer. The dominant paradigm holds that EREs are expressed i...
Citation: Genome Medicine 2020 12:40 -
The burden of waiting to access pain clinic services: perceptions and experiences of patients with rheumatic conditions
Extensive waiting times before receiving services is a major barrier to adequate pain management. Waiting times may have a detrimental impact on patients’ conditions and quality of life. However, there remains...
Citation: BMC Health Services Research 2021 21:160 -
“It feels like an endless fight”: a qualitative study exploring healthcare utilization of persons with rheumatic conditions waiting for pain clinic admission
Individuals living with a rheumatic pain condition can face delays in accessing pain clinics, which prevents them from receiving timely treatment. Little is known regarding their specific healthcare utilizatio...
Citation: BMC Musculoskeletal Disorders 2022 23:878 -
Knowledge and appropriateness of care of family physicians and physiotherapists in the management of shoulder pain: a survey study in the province of Quebec, Canada
Shoulder pain is difficult to diagnose and treat with half of those affected still symptomatic six months after initial consultation. This may be explained by primary care management not conforming to evidence...
Citation: BMC Primary Care 2023 24:49 -
A case report of severe tuberous sclerosis complex detected in utero and linked to a novel duplication in the TSC2 gene
Disease severity is tremendously variable in tuberous sclerosis complex (TSC). In contrast with the detailed guidelines available for TSC diagnosis and management, clinical practice lacks adequate tools to eva...
Citation: BMC Neurology 2020 20:324 -
Defining novel parameters for the optimal priming and expansion of minor histocompatibility antigen-specific T cells in culture
Adoptive transfer of minor histocompatibility antigen (MiHA)-specific T cells is a promising therapy for patients with hematological cancers. However, the efficacy of the transferred cells is hampered by the a...
Citation: Journal of Translational Medicine 2015 13:123