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50 result(s) for 'author#Robert Sauerwein' within BMC

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  1. Since 2000, under the Fifth and subsequent Framework Programmes, the European Commission has funded research to spur the development of a malaria vaccine. This funding has contributed to the promotion of an in...

    Authors: Regitze L Thøgersen, Anthony A Holder, Adrian VS Hill, David E Arnot, Egeruan B Imoukhuede and Odile Leroy
    Citation: Malaria Journal 2011 10:255
  2. A 23-year-old healthy male volunteer took part in a clinical trial in which the volunteer took chloroquine chemoprophylaxis and received three intradermal doses at four-week intervals of aseptic, purified Plasmod...

    Authors: Maurits PA van Meer, Guido JH Bastiaens, Mohamed Boulaksil, Quirijn de Mast, Anusha Gunasekera, Stephen L Hoffman, Gheorghe Pop, André JAM van der Ven and Robert W Sauerwein
    Citation: Malaria Journal 2014 13:38
  3. The induction of sterile immunity and long lasting protection against malaria has been effectively achieved by immunization with sporozoites attenuated by gamma-irradiation or through deletion of genes. For mi...

    Authors: Bruno Douradinha, Melissa van Dijk, Geert-Jan van Gemert, Shahid M Khan, Chris J Janse, Andy P Waters, Robert W Sauerwein, Adrian JF Luty, Bruno Silva-Santos, Maria M Mota and Sabrina Epiphanio
    Citation: Journal of Immune Based Therapies and Vaccines 2011 9:6
  4. Mosquito-feeding assays are important tools to guide the development and support the evaluation of transmission-blocking interventions. These functional bioassays measure the sporogonic development of gametocy...

    Authors: Isaie J. Reuling, Will J. R. Stone, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Rianne Siebelink-Stoter, Wouter Graumans, Kjerstin Lanke, Teun Bousema and Robert W. Sauerwein
    Citation: Malaria Journal 2017 16:315
  5. Measurement of liver stage development is of key interest in malaria biology and vaccine studies. Parasite development in liver cells can be visualized in real-time, both in culture and in live mice, using a t...

    Authors: Ivo Ploemen, Marije Behet, Krystelle Nganou-Makamdop, Geert-Jan van Gemert, Else Bijker, Cornelus Hermsen and Robert Sauerwein
    Citation: Malaria Journal 2011 10:350
  6. The Plasmodium falciparum parasite is transmitted in its sexual gametocyte stage from man to mosquito and as asexual sporozoites from mosquito to man. Developing gametocytes sequester preferentially in the bone m...

    Authors: Christian W Wang, Steven B Mwakalinga, Colin J Sutherland, Samana Schwank, Sarah Sharp, Cornelus C Hermsen, Robert W Sauerwein, Thor G Theander and Thomas Lavstsen
    Citation: Malaria Journal 2010 9:147
  7. Studies on Plasmodium falciparum gametocyte development and dynamics have almost exclusively focused on patients treated with antimalarial drugs, while the majority of parasite carriers in endemic areas are asymp...

    Authors: J Teun Bousema, Louis C Gouagna, Chris J Drakeley, Annemiek M Meutstege, Bernard A Okech, Ikupa NJ Akim, John C Beier, John I Githure and Robert W Sauerwein
    Citation: Malaria Journal 2004 3:18
  8. The ability to culture Plasmodium falciparum continuously in vitro has enabled stable access to asexual and sexual parasites for malaria research. The portfolio of isolates has remained limited and research is st...

    Authors: Marga van de Vegte-Bolmer, Wouter Graumans, Rianne Stoter, Geert-Jan van Gemert, Robert Sauerwein, Katharine A. Collins and Teun Bousema
    Citation: Malaria Journal 2021 20:381
  9. Chimeric mice with humanized livers represent a promising tool for infections with Plasmodium falciparum to evaluate novel methods for prevention and treatment of pre-erythrocytic stages. Adequate assessment of h...

    Authors: Lander Foquet, Cornelus C Hermsen, Geert-Jan van Gemert, Louis Libbrecht, Robert Sauerwein, Philip Meuleman and Geert Leroux-Roels
    Citation: Malaria Journal 2013 12:430
  10. Parasites causing severe malaria in non-immune patients express a restricted subset of variant surface antigens (VSA), which are better recognized by immune sera than VSA expressed during non-severe disease in...

    Authors: Thomas Lavstsen, Pamela Magistrado, Cornelus C Hermsen, Ali Salanti, Anja TR Jensen, Robert Sauerwein, Lars Hviid, Thor G Theander and Trine Staalsoe
    Citation: Malaria Journal 2005 4:21
  11. Drug resistant malaria poses an increasing public health problem in Indonesia, especially eastern Indonesia, where malaria is highly endemic. Widespread chloroquine (CQ) resistance and increasing sulphadoxine-...

    Authors: Puji BS Asih, William O Rogers, Agustina I Susanti, Agus Rahmat, Ismail E Rozi, Mariska A Kusumaningtyas, Krisin, Sekartuti, Rita M Dewi, Farah N Coutrier, Awalludin Sutamihardja, Andre JAM van der Ven, Robert W Sauerwein and Din Syafruddin
    Citation: Malaria Journal 2009 8:222
  12. Malaria transmission depends on the presence of gametocytes in the peripheral blood. In this study, the age-dependency of gametocytaemia was examined by microscopy and molecular tools.

    Authors: André Lin Ouédraogo, Teun Bousema, Sake J de Vlas, Nadine Cuzin-Ouattara, Jan-Peter Verhave, Chris Drakeley, Adrian JF Luty and Robert Sauerwein
    Citation: Malaria Journal 2010 9:281
  13. Adequate malaria diagnosis and treatment remain major difficulties in rural sub-Saharan Africa. These issues deserve renewed attention in the light of first-line treatment with expensive artemisinin-combinatio...

    Authors: Charles Mwanziva, Seif Shekalaghe, Arnold Ndaro, Bianca Mengerink, Simon Megiroo, Frank Mosha, Robert Sauerwein, Chris Drakeley, Roly Gosling and Teun Bousema
    Citation: Malaria Journal 2008 7:232
  14. Long-lasting and sterile protective immunity against Plasmodium falciparum can be achieved by immunization of malaria-naive human volunteers under chloroquine prophylaxis with sporozoites delivered by mosquito bi...

    Authors: Marije C Behet, Lander Foquet, Geert-Jan van Gemert, Else M Bijker, Philip Meuleman, Geert Leroux-Roels, Cornelus C Hermsen, Anja Scholzen and Robert W Sauerwein
    Citation: Malaria Journal 2014 13:136
  15. Therapeutic blood plasma concentrations of anti-malarial drugs are essential for successful treatment. Pharmacokinetics of pharmaceutical compounds are dependent of adsorption, distribution, metabolism, and ex...

    Authors: Sanna R Rijpma, Jeroen JMW van den Heuvel, Maarten van der Velden, Robert W Sauerwein, Frans GM Russel and Jan B Koenderink
    Citation: Malaria Journal 2014 13:359
  16. Both chloroquine (CQ) and sulfadoxine-pyrimethamine (SP) are failing drugs in much of sub-Saharan Africa. Previous findings suggest an association between resistance to CQ and to SP in vivo, in vitro, and on the ...

    Authors: Frank P Mockenhaupt, J Teun Bousema, Teunis A Eggelte, Stephan Ehrhardt, Rowland N Otchwemah, Robert W Sauerwein and Ulrich Bienzle
    Citation: Malaria Journal 2005 4:42
  17. Low density Plasmodium falciparum infections, below the microscopic detection limit, may play an important role in maintaining malaria transmission in low endemic areas as well as contribute to the maintenance of...

    Authors: Seif Shekalaghe, Michael Alifrangis, Charles Mwanziva, Anders Enevold, Steve Mwakalinga, Humphrey Mkali, Reginald Kavishe, Alphaxard Manjurano, Robert Sauerwein, Chris Drakeley and Teun Bousema
    Citation: BMC Infectious Diseases 2009 9:69