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17 result(s) for 'author#Peter JM Valk' within BMC
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Citation: Clinical and Translational Allergy 2017 7(Suppl 1):10
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Challenges to evaluating complex interventions: a content analysis of published papers
There is continuing interest among practitioners, policymakers and researchers in the evaluation of complex interventions stemming from the need to further develop the evidence base on the effectiveness of hea...
Citation: BMC Public Health 2013 13:568 -
5th Pediatric Allergy and Asthma Meeting (PAAM)
Citation: Clinical and Translational Allergy 2018 8(Suppl 2):26 -
Non-AIDS defining cancers in the D:A:D Study - time trends and predictors of survival: a cohort study
Non-AIDS defining cancers (NADC) are an important cause of morbidity and mortality in HIV-positive individuals. Using data from a large international cohort of HIV-positive individuals, we described the incide...
Citation: BMC Infectious Diseases 2013 13:471 -
HeatMapper: powerful combined visualization of gene expression profile correlations, genotypes, phenotypes and sample characteristics
Accurate interpretation of data obtained by unsupervised analysis of large scale expression profiling studies is currently frequently performed by visually combining sample-gene heatmaps and sample characteris...
Citation: BMC Bioinformatics 2006 7:337 -
Heme metabolism genes Downregulated in COPD Cachexia
Cachexia contributes to increased mortality and reduced quality of life in Chronic Obstructive Pulmonary Disease (COPD) and may be associated with underlying gene expression changes. Our goal was to identify d...
Citation: Respiratory Research 2020 21:100 -
A standardized microarray assay for the independent gene expression markers in AML: EVI1 and BAALC
High levels of BAALC, ERG, EVI1 and MN1 expression have been associated with shorter overall survival in AML but standardized and clinically validated assays are lacking. We have therefore developed and optimized...
Citation: Experimental Hematology & Oncology 2013 2:7 -
Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor stimulation
High-throughput experiments, such as with DNA microarrays, typically result in hundreds of genes potentially relevant to the process under study, rendering the interpretation of these experiments problematic. ...
Citation: BMC Bioinformatics 2007 8:14 -
SNPExpress: integrated visualization of genome-wide genotypes, copy numbers and gene expression levels
Accurate analyses of comprehensive genome-wide SNP genotyping and gene expression data sets is challenging for many researchers. In fact, obtaining an integrated view of both large scale SNP genotyping and gen...
Citation: BMC Genomics 2008 9:41 -
Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons: the D:A:D study
No consensus exists on how to define abnormally rapid deterioration in renal function (Rapid Progression, RP). We developed an operational definition of RP in HIV-positive persons with baseline estimated glome...
Citation: BMC Nephrology 2014 15:51 -
The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies
Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and summarized, generating the final probe set ...
Citation: BMC Bioinformatics 2006 7:105 -
Observational cohort study of rilpivirine (RPV) utilization in Europe
Data on safety and effectiveness of RPV from the real-world setting as well as comparisons with other NNRTIs such as efavirenz (EFV) remain scarce.
Citation: AIDS Research and Therapy 2022 19:38 -
HIV testing week 2015: lowering barriers for HIV testing among high-risk groups in Amsterdam
Evaluation of the HIV Testing Week (HTW) 2015 in Amsterdam: the number of (positive) tested persons, characteristics and testing history of the tested population, the differences in attendance per location and...
Citation: BMC Infectious Diseases 2017 17:529 -
Pelvic floor rehabilitation to improve functional outcome and quality of life after surgery for rectal cancer: study protocol for a randomized controlled trial (FORCE trial)
After low anterior resection (LAR), up to 90% of patients develop anorectal dysfunction. Especially fecal incontinence has a major impact on the physical, psychological, social, and emotional functioning of th...
Citation: Trials 2020 21:112 -
Is there continued evidence for an association between abacavir usage and myocardial infarction risk in individuals with HIV? A cohort collaboration
In March 2008, the D:A:D study published results demonstrating an increased risk of myocardial infarction (MI) for patients on abacavir (ABC). We describe changes to the use of ABC since this date, and investi...
Citation: BMC Medicine 2016 14:61 -
An Internet-based self-help intervention for people with HIV and depressive symptoms: study protocol for a randomized controlled trial
Many people living with HIV suffer from depressive symptoms. In a previous pilot study, self-help cognitive behavioral therapy (in booklet format) was found to be effective in treating depressive symptoms in p...
Citation: Trials 2016 17:172 -
Effect of abacavir on sustained virologic response to HCV treatment in HIV/HCV co-infected patients, Cohere in Eurocoord
Contradicting results on the effect of abacavir (ABC) on hepatitis C virus (HCV) treatment responses in HIV/HCV co-infected patients have been reported. We evaluated the influence of ABC on the response to peg...
Citation: BMC Infectious Diseases 2015 15:498