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12 result(s) for 'author#Mengling Huang' within BMC
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Citation: Burns & Trauma 2019 7(Suppl 1):27
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Quantitative lung morphology: semi-automated measurement of mean linear intercept
Quantifying morphologic changes is critical to our understanding of the pathophysiology of the lung. Mean linear intercept (MLI) measures are important in the assessment of clinically relevant pathology, such ...
Citation: BMC Pulmonary Medicine 2019 19:206 -
Role of circulating free DNA in evaluating clinical tumor burden and predicting survival in Chinese metastatic colorectal cancer patients
The aim of this study was to explore the utility of circulating free DNA (cfDNA) in the evaluation of clinical tumor burden and survival in Chinese patients with metastatic colorectal cancer (mCRC) and to prel...
Citation: BMC Cancer 2020 20:1006 -
Transcription-coupled structural dynamics of topologically associating domains regulate replication origin efficiency
Metazoan cells only utilize a small subset of the potential DNA replication origins to duplicate the whole genome in each cell cycle. Origin choice is linked to cell growth, differentiation, and replication st...
Citation: Genome Biology 2021 22:206 -
Improvement of the anticancer efficacy of PD-1/PD-L1 blockade via combination therapy and PD-L1 regulation
Immune checkpoint molecules are promising anticancer targets, among which therapeutic antibodies targeting the PD-1/PD-L1 pathway have been widely applied to cancer treatment in clinical practice and have grea...
Citation: Journal of Hematology & Oncology 2022 15:24 -
GREM1/PPP2R3A expression in heterogeneous fibroblasts initiates pulmonary fibrosis
Fibroblasts have important roles in the synthesis and remodeling of extracellular matrix (ECM) proteins during pulmonary fibrosis. However, the spatiotemporal distribution of heterogeneous fibroblasts during d...
Citation: Cell & Bioscience 2022 12:123 -
A missing piece of the puzzle in pulmonary fibrosis: anoikis resistance promotes fibroblast activation
Pulmonary fibrosis initiates a pneumonic cascade that leads to fibroblast dysfunction characterized by excess proliferation. Anoikis is a physiological process that ensures tissue development and homeostasis. ...
Citation: Cell & Bioscience 2022 12:21 -
Dynamic enhancer transcription associates with reprogramming of immune genes during pattern triggered immunity in Arabidopsis
Enhancers are cis-regulatory elements present in eukaryote genomes, which constitute indispensable determinants of gene regulation by governing the spatiotemporal and quantitative expression dynamics of target...
Citation: BMC Biology 2022 20:165 -
ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10
Silicosis is a pulmonary fibrosis-associated disease caused by the inhalation of large amounts of free silicon dioxide (SiO2) that mainly manifests as early inflammation and late pulmonary fibrosis. As macrophage...
Citation: Respiratory Research 2022 23:204 -
Global transcriptome changes of elongating internode of sugarcane in response to mepiquat chloride
Mepiquat chloride (DPC) is a chemical that is extensively used to control internode growth and create compact canopies in cultured plants. Previous studies have suggested that DPC could also inhibit gibberelli...
Citation: BMC Genomics 2021 22:79 -
Comparative proteomics of three Chinese potato cultivars to improve understanding of potato molecular response to late blight disease
Late blight disease (LBD) caused by the pathogen Phytophthora infestans (PI), is the most devastating disease limiting potato (Solanum tuberosum) production globally. Currently, this disease pathogen is re-emergi...
Citation: BMC Genomics 2020 21:880 -
Biopsychosocial risk factors of depression during menopause transition in southeast China
More than 2 billion women are experiencing menopause transition in China and some of them suffered from depression; while the risk factors of depression during menopause transition were still unclearin China. ...
Citation: BMC Women's Health 2022 22:273