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8 result(s) for 'author#Laëtitia Michou' within BMC

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  1. Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) is involved in osteoclastogenesis with a key role in mononucleated osteoclasts fusion. We reported in patients with Paget’s disease of bone (PDB) a rare...

    Authors: Emilie Laurier, Nathalie Amiable, Edith Gagnon, Jacques P. Brown and Laëtitia Michou
    Citation: BMC Medical Genetics 2017 18:133
    Content type: Research article Published on:

  2. Recently, we proposed a classification of HLA-DRB1 alleles that reshapes the shared epitope hypothesis in rheumatoid arthritis (RA); according to this model, RA is associated with the RAA shared epitope sequen...

    Authors: Laëtitia Michou, Pascal Croiseau, Elisabeth Petit-Teixeira, Sophie Tezenas du Montcel, Isabelle Lemaire, Céline Pierlot, José Osorio, Wafa Frigui, Sandra Lasbleiz, Patrick Quillet, Thomas Bardin, Bernard Prum, Françoise Clerget-Darpoux and François Cornélis
    Citation: Arthritis Research & Therapy 2006 8:R79
    Content type: Research article Published on:

  3. We identified two families with Paget's disease of bone (PDB) linked to the p.Pro392Leu mutation within the SQSTM1 gene displaying a possible digenism. This study aimed at identifying this second genetic variant ...

    Authors: Mariam Dessay, Emile Couture, Halim Maaroufi, Frédéric Fournier, Edith Gagnon, Arnaud Droit, Jacques P. Brown and Laëtitia Michou
    Citation: BMC Medical Genomics 2022 15:41
    Content type: Research Published on:

  4. The protein tyrosine phosphatase nonreceptor type 22 (PTPN22) gene encodes for lymphoid tyrosine phosphatase LYP, involved in the negative regulation of early T-cell activation. An association has recently been r...

    Authors: Philippe Dieudé, Sophie Garnier, Laëtitia Michou, Elisabeth Petit-Teixeira, Elodie Glikmans, Céline Pierlot, Sandra Lasbleiz, Thomas Bardin, Bernard Prum and François Cornélis
    Citation: Arthritis Research & Therapy 2005 7:R1200
    Content type: Research article Published on:

  5. The integrin αvβ3, whose αv subunit is encoded by the ITGAV gene, plays a key role in angiogenesis. Hyperangiogenesis is involved in rheumatoid arthritis (RA) and the ITGAV gene is located in 2q31, one of the sug...

    Authors: Laurent Jacq, Sophie Garnier, Philippe Dieudé, Laëtitia Michou, Céline Pierlot, Paola Migliorini, Alejandro Balsa, René Westhovens, Pilar Barrera, Helena Alves, Carlos Vaz, Manuela Fernandes, Dora Pascual-Salcedo, Stefano Bombardieri, Jan Dequeker, Timothy R Radstake…
    Citation: Arthritis Research & Therapy 2007 9:R63
    Content type: Research article Published on:

  6. Precision medicine, as a personalized medicine approach based on biomarkers, is a booming field. In general, physicians and patients have a positive attitude toward precision medicine, but their knowledge and ...

    Authors: Sophie Ruel-Gagné, David Simonyan, Jean Légaré, Louis Bessette, Paul R. Fortin, Diane Lacaille, Maman Joyce Dogba and Laëtitia Michou
    Citation: BMC Rheumatology 2021 5:52
    Content type: Research article Published on:

  7. Mutations in the SQSTM1/p62 gene have been reported in Paget’s disease of bone (PDB), but they are not sufficient to induce the pagetic osteoclast (OC) phenotype. We hypothesized that specific RNA isoforms of OC-...

    Authors: Roscoe Klinck, Gino Laberge, Martine Bisson, Stephen McManus, Laëtitia Michou, Jacques P Brown and Sophie Roux
    Citation: BMC Medical Genetics 2014 15:98
    Content type: Research article Published on:

  8. Synovial infiltration of monocytes is commonly associated with inflammation in rheumatoid arthritis (RA). Toll-like receptors (TLRs) are innate sensors that recognize cell debris and microbial components in ho...

    Authors: Patricia Lacerte, Alexandre Brunet, Benoit Egarnes, Benjamin Duchêne, Jacques P. Brown and Jean Gosselin
    Citation: Arthritis Research & Therapy 2016 18:10
    Content type: Research article Published on: