Skip to main content

Search

15 result(s) for 'author#Kephas Otieno' within BMC

Page 1 of 1

Sort by: Relevance | Date

  1. Monitoring local malaria transmission intensity is essential for planning evidence-based control strategies and evaluating their impact over time. Anti-malarial antibodies provide information on cumulative exp...

    Authors: Jacklyn Wong, Mary J Hamel, Chris J Drakeley, Simon Kariuki, Ya Ping Shi, Altaf A Lal, Bernard L Nahlen, Peter B Bloland, Kim A Lindblade, Vincent Were, Kephas Otieno, Peter Otieno, Chris Odero, Laurence Slutsker, John M Vulule and John E Gimnig
    Citation: Malaria Journal 2014 13:451
    Content type: Research Published on:

  2. Artemether-lumefantrine (AL) was adopted as first-line treatment for uncomplicated malaria in Kenya in 2006. Monitoring drug efficacy at regular intervals is essential to prevent unnecessary morbidity and mort...

    Authors: Aarti Agarwal, Meredith McMorrow, Peter Onyango, Kephas Otieno, Christopher Odero, John Williamson, Simon Kariuki, Stephen Patrick Kachur, Laurence Slutsker and Meghna Desai
    Citation: Malaria Journal 2013 12:254
    Content type: Research Published on:

  3. Intermittent preventive treatment in pregnancy with sulfadoxine/pyrimethamine is contra-indicated in HIV-positive pregnant women receiving sulfamethoxazole/trimethoprim prophylaxis. Since mefloquine is being c...

    Authors: Michael Green, Kephas Otieno, Abraham Katana, Laurence Slutsker, Simon Kariuki, Peter Ouma, Raquel González, Clara Menendez, Feiko ter Kuile and Meghna Desai
    Citation: Malaria Journal 2016 15:7
    Content type: Research Published on:

  4. Although malaria control intervention has greatly decreased malaria morbidity and mortality in many African countries, further decline in parasite prevalence has stagnated in western Kenya. In order to assess ...

    Authors: Zhiyong Zhou, Rebecca M. Mitchell, Simon Kariuki, Christopher Odero, Peter Otieno, Kephas Otieno, Philip Onyona, Vincent Were, Ryan E. Wiegand, John E. Gimnig, Edward D. Walker, Meghna Desai and Ya Ping Shi
    Citation: Malaria Journal 2016 15:421
    Content type: Research Published on:

  5. Over the last two decades, the scale-up of vector control and changes in the first-line anti-malarial, from chloroquine (CQ) to sulfadoxine-pyrimethamine (SP) and then to artemether-lumefantrine (AL), have res...

    Authors: Zhiyong Zhou, John E. Gimnig, Sheila B. Sergent, Ying Liu, Bernard Abong’o, Kephas Otieno, Winnie Chebore, Monica P. Shah, John Williamson, Feiko O. ter Kuile, Mary J. Hamel, Simon Kariuki, Meghna Desai, Aaron M. Samuels, Edward D. Walker and Ya Ping Shi
    Citation: Malaria Journal 2022 21:265
    Content type: Research Published on:

  6. Detection of malaria parasitaemia in samples that are negative by rapid diagnostic tests (RDTs) requires resource-intensive molecular tools. While pooled testing using a two-step strategy provides a cost-savin...

    Authors: Monica P. Shah, Winnie Chebore, Robert H. Lyles, Kephas Otieno, Zhiyong Zhou, Mateusz Plucinski, Lance A. Waller, Wycliffe Odongo, Kim A. Lindblade, Simon Kariuki, Aaron M. Samuels, Meghna Desai, Rebecca M. Mitchell and Ya Ping Shi
    Citation: Malaria Journal 2022 21:319
    Content type: Research Published on:

  7. Anti-malarial drug resistance remains a major threat to global malaria control efforts. In Africa, Plasmodium falciparum remains susceptible to artemisinin-based combination therapy (ACT), but the emergence of re...

    Authors: Winnie Chebore, Zhiyong Zhou, Nelli Westercamp, Kephas Otieno, Ya Ping Shi, Sheila B. Sergent, Kelsey Anne Rondini, Samaly Souza Svigel, Benard Guyah, Venkatachalam Udhayakumar, Eric S. Halsey, Aaron M. Samuels and Simon Kariuki
    Citation: Malaria Journal 2020 19:291
    Content type: Research Published on:

  8. Resistance to sulphadoxine-pyrimethamine (SP) in Plasmodium falciparum parasites is associated with mutations in the dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes and has spread worldwi...

    Authors: Nnaemeka C Iriemenam, Monica Shah, Wangeci Gatei, Anna M van Eijk, John Ayisi, Simon Kariuki, Jodi Vanden Eng, Simon O Owino, Ashima A Lal, Yusuf O Omosun, Kephas Otieno, Meghna Desai, Feiko O ter Kuile, Bernard Nahlen, Julie Moore, Mary J Hamel…
    Citation: Malaria Journal 2012 11:134
    Content type: Research Published on:

  9. Prompt diagnosis and effective malaria treatment is a key strategy in malaria control. However, the recommended diagnostic methods, microscopy and rapid diagnostic tests (RDTs), are not supported by robust qu...

    Authors: James Gachugia, Winnie Chebore, Kephas Otieno, Caroline Wangari Ngugi, Adano Godana and Simon Kariuki
    Citation: Malaria Journal 2020 19:329
    Content type: Research Published on:

  10. Simultaneous infection with multiple malaria parasite strains is common in high transmission areas. Quantifying the number of strains per host, or the multiplicity of infection (MOI), provides additional paras...

    Authors: Rebecca M. Mitchell, Zhiyong Zhou, Mili Sheth, Sheila Sergent, Michael Frace, Vishal Nayak, Bin Hu, John Gimnig, Feiko ter Kuile, Kim Lindblade, Laurence Slutsker, Mary J. Hamel, Meghna Desai, Kephas Otieno, Simon Kariuki, Ymir Vigfusson…
    Citation: Malaria Journal 2021 20:92
    Content type: Research Published on:

  11. Most human Plasmodium infections in western Kenya are asymptomatic and are believed to contribute importantly to malaria transmission. Elimination of asymptomatic infections requires active treatment approaches, ...

    Authors: Aaron M. Samuels, Nobert Awino, Wycliffe Odongo, Benard Abong’o, John Gimnig, Kephas Otieno, Ya Ping Shi, Vincent Were, Denise Roth Allen, Florence Were, Tony Sang, David Obor, John Williamson, Mary J. Hamel, S. Patrick Kachur, Laurence Slutsker…
    Citation: Malaria Journal 2017 16:240
    Content type: Case study Published on:

  12. Malaria transmission is high in western Kenya and the asymptomatic infected population plays a significant role in driving the transmission. Mathematical modelling and simulation programs suggest that interven...

    Authors: Norbert Awino Odero, Aaron M. Samuels, Wycliffe Odongo, Bernard Abong’o, John Gimnig, Kephas Otieno, Christopher Odero, David Obor, Maurice Ombok, Vincent Were, Tony Sang, Mary J. Hamel, S. Patrick Kachur, Laurence Slutsker, Kim A. Lindblade, Simon Kariuki…
    Citation: Malaria Journal 2019 18:255
    Content type: Research Published on:

  13. Parasite prevalence has been used widely as a measure of malaria transmission, especially in malaria endemic areas. However, its contribution and relationship to malaria mortality across different age groups h...

    Authors: Sammy Khagayi, Meghna Desai, Nyaguara Amek, Vincent Were, Eric Donald Onyango, Christopher Odero, Kephas Otieno, Godfrey Bigogo, Stephen Munga, Frank Odhiambo, Mary J. Hamel, Simon Kariuki, Aaron M. Samuels, Laurence Slutsker, John Gimnig and Penelope Vounatsou
    Citation: Malaria Journal 2019 18:247
    Content type: Research Published on:

  14. Although it is well known that drug pressure selects for drug-resistant parasites, the role of transmission reduction by insecticide-treated bed nets (ITNs) on drug resistance remains unclear. In this study, t...

    Authors: Monica Shah, Yusuf Omosun, Ashima Lal, Christopher Odero, Wangeci Gatei, Kephas Otieno, John E Gimnig, Feiko ter Kuile, William A Hawley, Bernard Nahlen, Simon Kariuki, Edward Walker, Laurence Slutsker, Mary Hamel and Ya Ping Shi
    Citation: Malaria Journal 2015 14:75
    Content type: Research Published on:

  15. Iron-deficient erythropoiesis results in excess formation of zinc protoporphyrin (ZPP), which can be measured instantly and at low assay cost using portable haematofluorometers. ZPP is used as a screening mark...

    Authors: Martin N Mwangi, Sumi Maskey, Pauline EA Andang’o, Noel K Shinali, Johanna M Roth, Laura Trijsburg, Alice M Mwangi, Han Zuilhof, Barend van Lagen, Huub FJ Savelkoul, Ayşe Y Demir and Hans Verhoef
    Citation: BMC Medicine 2014 12:229
    Content type: Research article Published on: