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24 result(s) for 'author#Katherine Belov' within BMC
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Citation: Genome Biology 2004 5:spotlight-20041029-01
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Genomics by the beach
A report on the 35th Annual Lorne Genome Conference 2014 held in Lorne, Victoria, Australia, February 16–18, 2014.
Citation: Genome Biology 2014 15:304 -
Immunome database for marsupials and monotremes
To understand the evolutionary origins of our own immune system, we need to characterise the immune system of our distant relatives, the marsupials and monotremes. The recent sequencing of the genomes of two m...
Citation: BMC Immunology 2011 12:48 -
Are there unequivocal criteria to label a given protein as a toxin? Permissive versus conservative annotation processes
Citation: Genome Biology 2013 14:406 -
Erratum to: Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development
Citation: Genome Biology 2011 12:414 -
Transcriptomic analysis supports similar functional roles for the two thymuses of the tammar wallaby
The thymus plays a critical role in the development and maturation of T-cells. Humans have a single thoracic thymus and presence of a second thymus is considered an anomaly. However, many vertebrates have mult...
Citation: BMC Genomics 2011 12:420 -
In silico identification of opossum cytokine genes suggests the complexity of the marsupial immune system rivals that of eutherian mammals
Cytokines are small proteins that regulate immunity in vertebrate species. Marsupial and eutherian mammals last shared a common ancestor more than 180 million years ago, so it is not surprising that attempts t...
Citation: Immunome Research 2006 2:4 -
From reference genomes to population genomics: comparing three reference-aligned reduced-representation sequencing pipelines in two wildlife species
Recent advances in genomics have greatly increased research opportunities for non-model species. For wildlife, a growing availability of reference genomes means that population genetics is no longer restricted...
Citation: BMC Genomics 2019 20:453 -
The effects of group versus intensive housing on the retention of genetic diversity in insurance populations
Retention of genetic diversity and demographic sustainability are the cornerstones of conservation breeding success. In theory, monogamous breeding with equal reproductive output will retain genetic diversity ...
Citation: BMC Zoology 2018 3:2 -
Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development
We present the genome sequence of the tammar wallaby, Macropus eugenii, which is a member of the kangaroo family and the first representative of the iconic hopping mammals that symbolize Australia to be sequenced...
Citation: Genome Biology 2011 12:R81 -
Novel venom gene discovery in the platypus
To date, few peptides in the complex mixture of platypus venom have been identified and sequenced, in part due to the limited amounts of platypus venom available to study. We have constructed and sequenced a c...
Citation: Genome Biology 2010 11:R95 -
Antigen-presenting genes and genomic copy number variations in the Tasmanian devil MHC
The Tasmanian devil (Sarcophilus harrisii) is currently under threat of extinction due to an unusual fatal contagious cancer called Devil Facial Tumour Disease (DFTD). DFTD is caused by a clonal tumour cell line ...
Citation: BMC Genomics 2012 13:87 -
A first-generation integrated tammar wallaby map and its use in creating a tammar wallaby first-generation virtual genome map
The limited (2X) coverage of the tammar wallaby (Macropus eugenii) genome sequence dataset currently presents a challenge for assembly and anchoring onto chromosomes. To provide a framework for this assembly, it ...
Citation: BMC Genomics 2011 12:422 -
Looking like the locals - gut microbiome changes post-release in an endangered species
Captivity presents extreme lifestyle changes relative to the wild, and evidence of microbiome dysbiosis in captive animals is growing. The gut microbiome plays a crucial role in host health. Whilst captive bre...
Citation: Animal Microbiome 2019 1:8 -
The Tasmanian devil microbiome—implications for conservation and management
The Tasmanian devil, the world’s largest carnivorous marsupial, is at risk of extinction due to devil facial tumour disease (DFTD), a fatal contagious cancer. The Save the Tasmanian Devil Program has establish...
Citation: Microbiome 2015 3:76 -
Evolution of the avian β-defensin and cathelicidin genes
β-defensins and cathelicidins are two families of cationic antimicrobial peptides (AMPs) with a broad range of antimicrobial activities that are key components of the innate immune system. Due to their importa...
Citation: BMC Evolutionary Biology 2015 15:188 -
Selection on MHC class II supertypes in the New Zealand endemic Hochstetter’s frog
The New Zealand native frogs, family Leiopelmatidae, are among the most archaic in the world. Leiopelma hochstetteri (Hochstetter’s frog) is a small, semi-aquatic frog with numerous, fragmented populations scatte...
Citation: BMC Evolutionary Biology 2015 15:63 -
The tammar wallaby major histocompatibility complex shows evidence of past genomic instability
The major histocompatibility complex (MHC) is a group of genes with a variety of roles in the innate and adaptive immune responses. MHC genes form a genetically linked cluster in eutherian mammals, an organiza...
Citation: BMC Genomics 2011 12:421 -
MHC-linked and un-linked class I genes in the wallaby
MHC class I antigens are encoded by a rapidly evolving gene family comprising classical and non-classical genes that are found in all vertebrates and involved in diverse immune functions. However, there is a f...
Citation: BMC Genomics 2009 10:310 -
Evolution and comparative analysis of the MHC Class III inflammatory region
The Major Histocompatibility Complex (MHC) is essential for immune function. Historically, it has been subdivided into three regions (Class I, II, and III), but a cluster of functionally related genes within t...
Citation: BMC Genomics 2006 7:281