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36 result(s) for 'author#Jonathan Sterne' within BMC
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Citation: Trials 2017 18(Suppl 1):200
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Corticosteroid therapy for critically ill patients with COVID-19: A structured summary of a study protocol for a prospective meta-analysis of randomized trials
Primary objective: To estimate the effect of corticosteroids compared with usual care or placebo on mortality up to 28 days after randomization. Secondary objectives: To examine whether the effect of corticost...
Citation: Trials 2020 21:734 -
Cluster analysis of host cytokine responses to biodefense pathogens in a whole blood ex vivo exposure model (WEEM)
Rapid detection and therapeutic intervention for infectious and emerging diseases is a major scientific goal in biodefense and public health. Toward this end, cytokine profiles in human blood were investigated...
Citation: BMC Microbiology 2012 12:79 -
Recommendations for reporting of systematic reviews and meta-analyses of diagnostic test accuracy: a systematic review
This study is to perform a systematic review of existing guidance on quality of reporting and methodology for systematic reviews of diagnostic test accuracy (DTA) in order to compile a list of potential items ...
Citation: Systematic Reviews 2017 6:194 -
The reporting and handling of missing data in longitudinal studies of older adults is suboptimal: a methodological survey of geriatric journals
Missing data are common in longitudinal studies, and more so, in studies of older adults, who are susceptible to health and functional decline that limit completion of assessments. We assessed the extent, curr...
Citation: BMC Medical Research Methodology 2022 22:122 -
Primary Care implementation of Germ Defence, a digital behaviour change intervention to improve household infection control during the COVID-19 pandemic: A structured summary of a study protocol for a randomised controlled trial
To examine the effectiveness of randomising dissemination of the Germ Defence behaviour change website via GP practices across England UK.
Citation: Trials 2021 22:263 -
Evaluation of the Cochrane Collaboration’s tool for assessing the risk of bias in randomized trials: focus groups, online survey, proposed recommendations and their implementation
In 2008, the Cochrane Collaboration introduced a tool for assessing the risk of bias in clinical trials included in Cochrane reviews. The risk of bias (RoB) tool is based on narrative descriptions of evidence-...
Citation: Systematic Reviews 2014 3:37 -
Development of a method for adjusting trial results for biases in meta-analysis
Citation: Trials 2013 14(Suppl 1):P124 -
Estimating the effect of “treatment in the treated” - instrumental variable analysis vs conventional regression methods in the titre-2 trial in cardiac surgery
Citation: Trials 2015 16(Suppl 2):P147 -
Systematic review of the surgical management of rotator cuff repair with an augmentative patch: a feasibility study protocol
Shoulder pain is a common problem in the general population and is responsible for prolonged periods of disability, loss of productivity, absence from work and inability to carry out household activities. Rota...
Citation: Systematic Reviews 2018 7:187 -
Evaluation of the Cochrane tool for assessing risk of bias in randomized clinical trials: overview of published comments and analysis of user practice in Cochrane and non-Cochrane reviews
The Cochrane risk of bias tool for randomized clinical trials was introduced in 2008 and has frequently been commented on and used in systematic reviews. We wanted to evaluate the tool by reviewing published c...
Citation: Systematic Reviews 2016 5:80 -
Graphical presentation of diagnostic information
Graphical displays of results allow researchers to summarise and communicate the key findings of their study. Diagnostic information should be presented in an easily interpretable way, which conveys both test ...
Citation: BMC Medical Research Methodology 2008 8:20 -
Statistics review 12: Survival analysis
This review introduces methods of analyzing data arising from studies where the response variable is the length of time taken to reach a certain end-point, often death. The Kaplan–Meier methods, log rank test ...
Citation: Critical Care 2004 8:389 -
Use of machine learning to analyse routinely collected intensive care unit data: a systematic review
Intensive care units (ICUs) face financial, bed management, and staffing constraints. Detailed data covering all aspects of patients’ journeys into and through intensive care are now collected and stored in el...
Citation: Critical Care 2019 23:284 -
Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial
Sociodemographic characteristics are associated with participating in cancer screening and trials. We compared the characteristics of those responding with those not responding to a single invitation for prost...
Citation: Trials 2016 17:497 -
The diagnosis of urinary tract infections in young children (DUTY): protocol for a diagnostic and prospective observational study to derive and validate a clinical algorithm for the diagnosis of UTI in children presenting to primary care with an acute illness
Urinary tract infection (UTI) is common in children, and may cause serious illness and recurrent symptoms. However, obtaining a urine sample from young children in primary care is challenging and not feasible ...
Citation: BMC Infectious Diseases 2012 12:158 -
Joint modelling rationale for chained equations
Chained equations imputation is widely used in medical research. It uses a set of conditional models, so is more flexible than joint modelling imputation for the imputation of different types of variables (e.g...
Citation: BMC Medical Research Methodology 2014 14:28 -
Ongoing monitoring of data clustering in multicenter studies
Multicenter study designs have several advantages, but the possibility of non-random measurement error resulting from procedural differences between the centers is a special concern. While it is possible to ad...
Citation: BMC Medical Research Methodology 2012 12:29 -
Is MRI better than CT for detecting a vascular component to dementia? A systematic review and meta-analysis
Identification of causes of dementia soon after symptom onset is important, because appropriate treatment of some causes of dementia can slow or halt its progression or enable symptomatic treatment where appro...
Citation: BMC Neurology 2012 12:33 -
A review of reporting of participant recruitment and retention in RCTs in six major journals
Poor recruitment and retention of participants in randomised controlled trials (RCTs) is problematic but common. Clear and detailed reporting of participant flow is essential to assess the generalisability and...
Citation: Trials 2009 10:52