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12 result(s) for 'author#Ioannis Xanthakis' within BMC

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  1. We present the case of a patient who presented with anaplastic thyroid carcinoma with a solitary large liver metastasis. Hepatic metastases are extremely rare in anaplastic thyroid carcinoma.

    Authors: Alexandra Adamidou, Panagiotis Kotsaftis, Maria Vlachou, Afroditi Haritanti, Ioannis Xanthakis, Anestis Zantidis and George Ntaios
    Citation: Cases Journal 2009 2:41
    Content type: Case Report Published on:

  2. Metronomic chemotherapy is considered an anti-angiogenic therapy that involves chronic administration of low-dose chemotherapy at regular short intervals. We investigated the optimal metronomic dose of oral vi...

    Authors: Evangelos Briasoulis, Gerasimos Aravantinos, George Kouvatseas, Periklis Pappas, Eirini Biziota, Ioannis Sainis, Thomas Makatsoris, Ioannis Varthalitis, Ioannis Xanthakis, Antonios Vassias, George Klouvas, Ioannis Boukovinas, George Fountzilas, Kostantinos N Syrigos, Haralambos Kalofonos and Epaminontas Samantas
    Citation: BMC Cancer 2013 13:263
    Content type: Research article Published on:

  3. The HER2 gene has been established as a valid biological marker for the treatment of breast cancer patients with trastuzumab and probably other agents, such as paclitaxel and anthracyclines. The TOP2A gene has be...

    Authors: George Fountzilas, Urania Dafni, Mattheos Bobos, Vassiliki Kotoula, Anna Batistatou, Ioannis Xanthakis, Christos Papadimitriou, Ioannis Kostopoulos, Triantafillia Koletsa, Eleftheria Tsolaki, Despina Televantou, Eleni Timotheadou, Angelos Koutras, George Klouvas, Epaminontas Samantas, Nikolaos Pisanidis…
    Citation: BMC Cancer 2013 13:163
    Content type: Research article Published on:

  4. The treatment paradigm in advanced renal cell carcinoma (RCC) has changed in the recent years. Sunitinib has been established as a new standard for first-line therapy. We studied the prognostic significance of...

    Authors: Aristotelis Bamias, Alexandra Karadimou, Sofia Lampaki, George Lainakis, Lia Malettou, Eleni Timotheadou, Kostas Papazisis, Charalambos Andreadis, Loukas Kontovinis, Ioannis Anastasiou, Kostas Stravodimos, Ioannis Xanthakis, Andreas Skolarikos, Christos Christodoulou, Kostas Syrigos, Christos Papandreou…
    Citation: BMC Cancer 2010 10:45
    Content type: Research article Published on:

  5. The aim was to compare two standard chemotherapy regimens combined with bevacizumab as first-line treatment in patients with metastatic colorectal cancer.

    Authors: Dimitrios Pectasides, George Papaxoinis, Konstantine T Kalogeras, Anastasia G Eleftheraki, Ioannis Xanthakis, Thomas Makatsoris, Epaminondas Samantas, Ioannis Varthalitis, Pavlos Papakostas, Nikitas Nikitas, Christos N Papandreou, George Pentheroudakis, Eleni Timotheadou, Angelos Koutras, Joseph Sgouros, Dimitrios Bafaloukos…
    Citation: BMC Cancer 2012 12:271
    Content type: Research article Published on:

  6. The epidermal growth factor receptor (EGFR) is over-expressed in 70–75% of colorectal adenocarcinomas (CRC). The anti-EGFR monoclonal antibody cetuximab has been approved for the treatment of metastatic CRC, h...

    Authors: Evangelia Razis, Evangelos Briasoulis, Eleni Vrettou, Dimosthenis V Skarlos, Dimitrios Papamichael, Ioannis Kostopoulos, Epaminontas Samantas, Ioannis Xanthakis, Mattheos Bobos, Eleni Galanidi, Maria Bai, Ioanna Gikonti, Alona Koukouma, Georgia Kafiri, Pavlos Papakostas, Konstantine T Kalogeras…
    Citation: BMC Cancer 2008 8:234
    Content type: Research article Published on:

  7. More than half of patients with KRAS-wild type advanced colorectal cancer (CRC) fail anti-EGFR monoclonal antibodies. We studied EGFR-axis messenger RNA (mRNA) expression and RAS, RAF, PIK3CA mutations in orde...

    Authors: George Pentheroudakis, Vassiliki Kotoula, Wendy De Roock, George Kouvatseas, Pavlos Papakostas, Thomas Makatsoris, Demetris Papamichael, Ioannis Xanthakis, Joseph Sgouros, Despina Televantou, Georgia Kafiri, Athanassios C Tsamandas, Evangelia Razis, Eleni Galani, Dimitrios Bafaloukos, Ioannis Efstratiou…
    Citation: BMC Cancer 2013 13:49
    Content type: Research article Published on:

  8. Dose-dense sequential chemotherapy including anthracyclines and taxanes has been established in the adjuvant setting of high-risk operable breast cancer. However, the preferable taxane and optimal schedule of ...

    Authors: George Fountzilas, Urania Dafni, Christos Papadimitriou, Eleni Timotheadou, Helen Gogas, Anastasia G Eleftheraki, Ioannis Xanthakis, Christos Christodoulou, Angelos Koutras, Christos N Papandreou, Pavlos Papakostas, Spyros Miliaras, Christos Markopoulos, Constantine Dimitrakakis, Panagiotis Korantzopoulos, Charisios Karanikiotis…
    Citation: BMC Cancer 2014 14:515
    Content type: Research article Published on:

  9. Bevacizumab, an antibody neutralizing Vascular Endothelial Growth Factor (VEGF), is licensed for the management of patients with advanced colon cancer. However, tumor biomarkers identifying the molecular tumor...

    Authors: George Pentheroudakis, Vassiliki Kotoula, Elena Fountzilas, George Kouvatseas, George Basdanis, Ioannis Xanthakis, Thomas Makatsoris, Elpida Charalambous, Demetris Papamichael, Epaminontas Samantas, Pavlos Papakostas, Dimitrios Bafaloukos, Evangelia Razis, Christos Christodoulou, Ioannis Varthalitis, Nicholas Pavlidis…
    Citation: BMC Cancer 2014 14:111
    Content type: Research article Published on:

  10. The vast majority of patients with HER2-positive metastatic breast cancer (MBC) treated with trastuzumab eventually develop resistance to this agent. There is an unmet need therefore, for identifying biologica...

    Authors: George Fountzilas, Christos Christodoulou, Mattheos Bobos, Vassiliki Kotoula, Anastasia G Eleftheraki, Ioannis Xanthakis, Anna Batistatou, George Pentheroudakis, Nikolaos Xiros, Irene Papaspirou, Anna Koumarianou, Pavlos Papakostas, Dimitrios Bafaloukos, Dimosthenis V Skarlos and Konstantine T Kalogeras
    Citation: Journal of Translational Medicine 2012 10:212
    Content type: Research Published on:

  11. There is an unmet need for more efficient patient stratification for receiving trastuzumab in the metastatic breast cancer (mBC) setting, since only part of such patients benefit from the addition of this agen...

    Authors: Helen Gogas, Vassiliki Kotoula, Zoi Alexopoulou, Christos Christodoulou, Ioannis Kostopoulos, Mattheos Bobos, Georgia Raptou, Elpida Charalambous, Eleftheria Tsolaki, Ioannis Xanthakis, George Pentheroudakis, Angelos Koutras, Dimitrios Bafaloukos, Pavlos Papakostas, Gerasimos Aravantinos, Amanda Psyrri…
    Citation: Journal of Translational Medicine 2016 14:136
    Content type: Research Published on:

  12. Hereditary cancer predisposition syndromes are responsible for approximately 5–10% of all diagnosed cancer cases. In the past, single-gene analysis of specific high risk genes was used for the determination of...

    Authors: Georgios N. Tsaousis, Eirini Papadopoulou, Angela Apessos, Konstantinos Agiannitopoulos, Georgia Pepe, Stavroula Kampouri, Nikolaos Diamantopoulos, Theofanis Floros, Rodoniki Iosifidou, Ourania Katopodi, Anna Koumarianou, Christos Markopoulos, Konstantinos Papazisis, Vasileios Venizelos, Ioannis Xanthakis, Grigorios Xepapadakis…
    Citation: BMC Cancer 2019 19:535
    Content type: Research article Published on: