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12 result(s) for 'author#Guri Giaever' within BMC

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  1. Iron-deficiency anemia is the most prevalent form of anemia world-wide. The yeast Saccharomyces cerevisiae has been used as a model of cellular iron deficiency, in part because many of its cellular pathways are c...

    Authors: William J Jo, Jeung Hyoun Kim, Eric Oh, Daniel Jaramillo, Patricia Holman, Alex V Loguinov, Adam P Arkin, Corey Nislow, Guri Giaever and Chris D Vulpe
    Citation: BMC Genomics 2009 10:130
    Content type: Research article Published on:

  2. Single genome-wide screens for the effect of altered gene dosage on drug sensitivity in the model organism Saccharomyces cerevisiae provide only a partial picture of the mechanism of action of a drug.

    Authors: Danielle Kemmer, Lianne M McHardy, Shawn Hoon, Delphine Rebérioux, Guri Giaever, Corey Nislow, Calvin D Roskelley and Michel Roberge
    Citation: BMC Microbiology 2009 9:9
    Content type: Research article Published on:

  3. Because protonation affects the properties of almost all molecules in cells, cytosolic pH (pHc) is usually assumed to be constant. In the model organism yeast, however, pHc changes in response to the presence of ...

    Authors: Rick Orij, Malene L Urbanus, Franco J Vizeacoumar, Guri Giaever, Charles Boone, Corey Nislow, Stanley Brul and Gertien J Smits
    Citation: Genome Biology 2012 13:R80
    Content type: Research Published on:

  4. Target identification is a critical step in the lengthy and expensive process of drug development. Here, we describe a genome-wide screening platform that uses systematic overexpression of pooled human ORFs to...

    Authors: Anthony Arnoldo, Saranya Kittanakom, Lawrence E Heisler, Anthony B Mak, Andrey I Shukalyuk, Dax Torti, Jason Moffat, Guri Giaever and Corey Nislow
    Citation: Genome Medicine 2014 6:32
    Content type: Method Published on:

  5. Microarrays are an invaluable tool in many modern genomic studies. It is generally perceived that decreasing the size of microarray features leads to arrays with higher resolution (due to greater feature densi...

    Authors: Ron Ammar, Andrew M Smith, Lawrence E Heisler, Guri Giaever and Corey Nislow
    Citation: BMC Genomics 2009 10:471
    Content type: Methodology article Published on:

  6. Chemogenomic profiling is a powerful approach for understanding the genome-wide cellular response to small molecules. First developed in Saccharomyces cerevisiae, chemogenomic screens provide direct, unbiased ide...

    Authors: Marjan Barazandeh, Divya Kriti, Corey Nislow and Guri Giaever
    Citation: BMC Genomics 2022 23:197
    Content type: Research Published on:

  7. Chitosan oligosaccharide (COS), a deacetylated derivative of chitin, is an abundant, and renewable natural polymer. COS has higher antimicrobial properties than chitosan and is presumed to act by disrupting/pe...

    Authors: Maria DLA Jaime, Luis Vicente Lopez-Llorca, Ana Conesa, Anna Y Lee, Michael Proctor, Lawrence E Heisler, Marinella Gebbia, Guri Giaever, J Timothy Westwood and Corey Nislow
    Citation: BMC Genomics 2012 13:267
    Content type: Research article Published on:

  9. Chemical biology, the interfacial discipline of using small molecules as probes to investigate biology, is a powerful approach of developing specific, rapidly acting tools that can be applied across organisms....

    Authors: Simon E Alfred, Anuradha Surendra, Chris Le, Ken Lin, Alexander Mok, Iain M Wallace, Michael Proctor, Malene L Urbanus, Guri Giaever and Corey Nislow
    Citation: Genome Biology 2012 13:R105
    Content type: Method Published on:

  10. We systematically analyzed the relationships between gene fitness profiles (co-fitness) and drug inhibition profiles (co-inhibition) from several hundred chemogenomic screens in yeast. Co-fitness predicted gen...

    Authors: Maureen E Hillenmeyer, Elke Ericson, Ronald W Davis, Corey Nislow, Daphne Koller and Guri Giaever
    Citation: Genome Biology 2010 11:R30
    Content type: Method Published on:

  11. Genome-wide screening in human and mouse cells using RNA interference and open reading frame over-expression libraries is rapidly becoming a viable experimental approach for many research labs. There are a var...

    Authors: Troy Ketela, Lawrence E Heisler, Kevin R Brown, Ron Ammar, Dahlia Kasimer, Anuradha Surendra, Elke Ericson, Kim Blakely, Dina Karamboulas, Andrew M Smith, Tanja Durbic, Anthony Arnoldo, Kahlin Cheung-Ong, Judice LY Koh, Shuba Gopal, Glenn S Cowley…
    Citation: BMC Genomics 2011 12:213
    Content type: Methodology article Published on: