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28 result(s) for 'author#Guillaume Leblanc' within BMC
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Citation: Allergy, Asthma & Clinical Immunology 2019 15(Suppl 2):17
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Meeting abstracts from the 4th International Clinical Trials Methodology Conference (ICTMC) and the 38th Annual Meeting of the Society for Clinical Trials
Citation: Trials 2017 18(Suppl 1):200 -
Publisher Correction: Penetrance estimation of Alzheimer disease in SORL1 loss-of-function variant carriers using a family-based strategy and stratification by APOE genotypes
Citation: Genome Medicine 2022 14:83 -
BMC Genomics reviewer acknowledgement 2015
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Citation: BMC Genomics 2016 17:168 -
BMP-9 expression in human traumatic heterotopic ossification: a case report
Heterotopic ossification (HO) is defined as the abnormal formation of mature bone in soft tissue, notably skeletal muscle. The morbidity of HO in polytraumatized patients impacts the functional outcome, impair...
Citation: Skeletal Muscle 2013 3:29 -
Added value of serial bio-adrenomedullin measurement in addition to lactate for the prognosis of septic patients admitted to ICU
Citation: Critical Care 2020 24:69 -
Evolving phenotypes of non-hospitalized patients that indicate long COVID
For some SARS-CoV-2 survivors, recovery from the acute phase of the infection has been grueling with lingering effects. Many of the symptoms characterized as the post-acute sequelae of COVID-19 (PASC) could ha...
Citation: BMC Medicine 2021 19:249 -
Perioperative use of gabapentinoids for the management of postoperative acute pain: protocol of a systematic review and meta-analysis
Opioids are commonly used for the management of postoperative pain, but their use is limited by important adverse events, such as respiratory depression and the potential for addiction. Multimodal opioid-spari...
Citation: Systematic Reviews 2019 8:24 -
Marked regional endothelial dysfunction in mottled skin area in patients with severe infections
Mottling around the knee, reflecting a reduced skin blood flow, is predictive of mortality in patients with septic shock. However, the causative pathophysiology of mottling remains unknown. We hypothesized tha...
Citation: Critical Care 2017 21:155 -
A Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial
Timing of initiation of kidney-replacement therapy (KRT) in critically ill patients remains controversial. The Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AK...
Citation: Critical Care 2022 26:255 -
The proteasome inhibitor MG132 reduces immobilization-induced skeletal muscle atrophy in mice
Skeletal muscle atrophy is a serious concern for the rehabilitation of patients afflicted by prolonged limb restriction. This debilitating condition is associated with a marked activation of NFκB activity. The...
Citation: BMC Musculoskeletal Disorders 2011 12:185 -
Integrative analysis of vascular endothelial cell genomic features identifies AIDA as a coronary artery disease candidate gene
Genome-wide association studies (GWAS) have identified hundreds of loci associated with coronary artery disease (CAD) and blood pressure (BP) or hypertension. Many of these loci are not linked to traditional r...
Citation: Genome Biology 2019 20:133 -
Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study
Adrenomedullin (ADM) regulates vascular tone and endothelial permeability during sepsis. Levels of circulating biologically active ADM (bio-ADM) show an inverse relationship with blood pressure and a direct re...
Citation: Critical Care 2018 22:354 -
Splenic volume and splenic vein diameter are independent pre-operative risk factors of portal vein thrombosis after splenectomy: a retrospective cohort study
Portal vein thrombosis (PVT) is a common complication following splenectomy. It affects between 5 and 55% of patients undergoing surgery with no clearly defined pre-operative risk factors. The aim of this stud...
Citation: BMC Surgery 2021 21:366 -
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development
Microphthalmia, anophthalmia, and coloboma (MAC) spectrum disease encompasses a group of eye malformations which play a role in childhood visual impairment. Although the predominant cause of eye malformations ...
Citation: BMC Biology 2023 21:22 -
Penetrance estimation of Alzheimer disease in SORL1 loss-of-function variant carriers using a family-based strategy and stratification by APOE genotypes
Alzheimer disease (AD) is a common complex disorder with a high genetic component. Loss-of-function (LoF) SORL1 variants are one of the strongest AD genetic risk factors. Estimating their age-related penetrance i...
Citation: Genome Medicine 2022 14:69 -
Correction to: Prevalence of anal symptoms in general practice: a prospective study
Following publication of the original article [1], the authors reported an error to one of the ‘study groups’ in the authorship section.
Citation: BMC Family Practice 2019 20:14 -
Factors associated with death in children with purpura fulminans: a French national prospective cohort study
Citation: Critical Care 2021 25:181 -
Corticotherapy for traumatic brain-injured Patients - The Corti-TC trial: study protocol for a randomized controlled trial
Traumatic brain injury (TBI) is a main cause of severe prolonged disability of young patients. Hospital acquired pneumonia (HAP) add to the morbidity and mortality of traumatic brain-injured patients. In one s...
Citation: Trials 2011 12:228 -
Prevalence of prescribed benzodiazepine long-term use in the French general population according to sociodemographic and clinical factors: findings from the CONSTANCES cohort
Data are lacking regarding the prevalence of benzodiazepine long-term use in the general population. Our aim was to examine the prevalence of prescribed benzodiazepine long-term use (BLTU) according to sociode...
Citation: BMC Public Health 2019 19:566