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16 result(s) for 'author#Amalia Mattiello' within BMC
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Citation: BMC Musculoskeletal Disorders 2016 17:62
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Circulating inflammatory biomarkers, adipokines and breast cancer risk—a case-control study nested within the EPIC cohort
Inflammation has been hypothesized to play a role in the development and progression of breast cancer and might differently impact breast cancer risk among pre and postmenopausal women. We performed a nested c...
Citation: BMC Medicine 2022 20:118 -
Determinants of non- response to a second assessment of lifestyle factors and body weight in the EPIC-PANACEA study
This paper discusses whether baseline demographic, socio-economic, health variables, length of follow-up and method of contacting the participants predict non-response to the invitation for a second assessment...
Citation: BMC Medical Research Methodology 2012 12:148 -
Reproductive factors and risk of hormone receptor positive and negative breast cancer: a cohort study
The association of reproductive factors with hormone receptor (HR)-negative breast tumors remains uncertain.
Citation: BMC Cancer 2013 13:584 -
The association of education with body mass index and waist circumference in the EPIC-PANACEA study
To examine the association of education with body mass index (BMI) and waist circumference (WC) in the European Prospective Investigation into Cancer and Nutrition (EPIC).
Citation: BMC Public Health 2011 11:169 -
Epigenome-wide association study for lifetime estrogen exposure identifies an epigenetic signature associated with breast cancer risk
It is well established that estrogens and other hormonal factors influence breast cancer susceptibility. We hypothesized that a woman’s total lifetime estrogen exposure accumulates changes in DNA methylation, ...
Citation: Clinical Epigenetics 2019 11:66 -
Development and validation of circulating CA125 prediction models in postmenopausal women
Cancer Antigen 125 (CA125) is currently the best available ovarian cancer screening biomarker. However, CA125 has been limited by low sensitivity and specificity in part due to normal variation between individ...
Citation: Journal of Ovarian Research 2019 12:116 -
Correlates of circulating ovarian cancer early detection markers and their contribution to discrimination of early detection models: results from the EPIC cohort
Ovarian cancer early detection markers CA125, CA15.3, HE4, and CA72.4 vary between healthy women, limiting their utility for screening.
Citation: Journal of Ovarian Research 2017 10:20 -
Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study
Increased serum neopterin had been described in older age two decades ago. Neopterin is a biomarker of systemic adaptive immune activation that could be potentially implicated in metabolic syndrome (MetS). Mea...
Citation: Immunity & Ageing 2016 13:5 -
Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis
Interest in the potential of DNA methylation in peripheral blood as a biomarker of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation measured in peripheral blood samples obta...
Citation: Clinical Epigenetics 2015 7:67 -
Gene-specific DNA methylation profiles and LINE-1 hypomethylation are associated with myocardial infarction risk
DNA methylation profiles are responsive to environmental stimuli and metabolic shifts. This makes DNA methylation a potential biomarker of environmental-related and lifestyle-driven diseases of adulthood. Ther...
Citation: Clinical Epigenetics 2015 7:133 -
Osteoprotegerin and breast cancer risk by hormone receptor subtype: a nested case-control study in the EPIC cohort
Circulating osteoprotegerin (OPG), a member of the receptor activator of nuclear factor kappa-B (RANK) axis, may influence breast cancer risk via its role as the decoy receptor for both the RANK ligand (RANKL)...
Citation: BMC Medicine 2017 15:26 -
Isocaloric substitution of carbohydrates with protein: the association with weight change and mortality among patients with type 2 diabetes
The health impact of dietary replacement of carbohydrates with protein for patients with type 2 diabetes is still debated. This study aimed to investigate the association between dietary substitution of carboh...
Citation: Cardiovascular Diabetology 2015 14:39 -
Smoking, Porphyromonas gingivalis and the immune response to citrullinated autoantigens before the clinical onset of rheumatoid arthritis in a Southern European nested case–control study
Antibodies to citrullinated proteins (ACPA) occur years before RA diagnosis. Porphyromonas gingivalis expresses its own peptidylarginine deiminase (PPAD), and is a proposed aetiological factor for the ACPA respon...
Citation: BMC Musculoskeletal Disorders 2015 16:331 -
Circulating prolactin and in situ breast cancer risk in the European EPIC cohort: a case-control study
The relationship between circulating prolactin and invasive breast cancer has been investigated previously, but the association between prolactin levels and in situ breast cancer risk has received less attention.
Citation: Breast Cancer Research 2015 17:49 -
Coffee and tea consumption and risk of pre- and postmenopausal breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study
Specific coffee subtypes and tea may impact risk of pre- and post-menopausal breast cancer differently. We investigated the association between coffee (total, caffeinated, decaffeinated) and tea intake and ris...
Citation: Breast Cancer Research 2015 17:15