Skip to main content

Search

15 result(s) for 'author#Alvina G. Lai' within BMC

Page 1 of 1

Sort by: Relevance | Date

  2. A1 Functional advantages of cell-type heterogeneity in neural circuits

    Authors: Tatyana O. Sharpee, Alain Destexhe, Mitsuo Kawato, Vladislav Sekulić, Frances K. Skinner, Daniel K. Wójcik, Chaitanya Chintaluri, Dorottya Cserpán, Zoltán Somogyvári, Jae Kyoung Kim, Zachary P. Kilpatrick, Matthew R. Bennett, Kresimir Josić, Irene Elices, David Arroyo, Rafael Levi…
    Citation: BMC Neuroscience 2016 17(Suppl 1):54
    Content type: Meeting abstracts Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  3. Since its discovery almost three decades ago, the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway has paved the road for understanding inflammatory and immunity processes rel...

    Authors: Wai Hoong Chang and Alvina G. Lai
    Citation: Molecular Medicine 2019 25:46
    Content type: Research article Published on:

  5. An Informatics Consult has been proposed in which clinicians request novel evidence from large scale health data resources, tailored to the treatment of a specific patient. However, the availability of such co...

    Authors: Alvina G. Lai, Wai Hoong Chang, Constantinos A. Parisinos, Michail Katsoulis, Ruth M. Blackburn, Anoop D. Shah, Vincent Nguyen, Spiros Denaxas, George Davey Smith, Tom R. Gaunt, Krishnarajah Nirantharakumar, Murray P. Cox, Donall Forde, Folkert W. Asselbergs, Steve Harris, Sylvia Richardson…
    Citation: BMC Medical Informatics and Decision Making 2021 21:281
    Content type: Research article Published on:

  6. People with liver disease are at increased risk of developing cardiovascular disease (CVD), however, there has yet been an investigation of incidence burden, risk, and premature mortality across a wide range o...

    Authors: Wai Hoong Chang, Stefanie H. Mueller, Sheng-Chia Chung, Graham R. Foster and Alvina G. Lai
    Citation: Journal of Translational Medicine 2022 20:2
    Content type: Research Published on:

  7. The objective of this study was to employ ensemble clustering and tree-based risk model approaches to identify interactions between clinicogenomic features for colorectal cancer using the 100,000 Genomes Project.

    Authors: Yuguo Wei, Nikolaos Papachristou, Stefanie Mueller, Wai Hoong Chang and Alvina G. Lai
    Citation: BMC Research Notes 2021 14:385
    Content type: Research note Published on:

  8. Low-frequency variants play an important role in breast cancer (BC) susceptibility. Gene-based methods can increase power by combining multiple variants in the same gene and help identify target genes.

    Authors: Stefanie H. Mueller, Alvina G. Lai, Maria Valkovskaya, Kyriaki Michailidou, Manjeet K. Bolla, Qin Wang, Joe Dennis, Michael Lush, Zomoruda Abu-Ful, Thomas U. Ahearn, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Volker Arndt, Kristan J. Aronson, Annelie Augustinsson…
    Citation: Genome Medicine 2023 15:7
    Content type: Research Published on:

  9. The AMP-activated protein kinase (AMPK) is an evolutionarily conserved regulator of cellular energy homeostasis. As a nexus for transducing metabolic signals, AMPK cooperates with other energy-sensing pathways...

    Authors: Wai Hoong Chang and Alvina G. Lai
    Citation: BMC Cancer 2020 20:773
    Content type: Research article Published on:

  10. Most animals employ telomerase, which consists of a catalytic subunit known as the telomerase reverse transcriptase (TERT) and an RNA template, to maintain telomere ends. Given the importance of TERT and telom...

    Authors: Alvina G. Lai, Natalia Pouchkina-Stantcheva, Alessia Di Donfrancesco, Gerda Kildisiute, Sounak Sahu and A. Aziz Aboobaker
    Citation: BMC Evolutionary Biology 2017 17:107
    Content type: Research article Published on:

  13. Despite much progress in cancer research, its incidence and mortality continue to rise. A robust biomarker that would predict tumor behavior is highly desirable and could improve patient treatment and prognosis.

    Authors: Wai Hoong Chang, Donall Forde and Alvina G. Lai
    Citation: Journal of Translational Medicine 2019 17:14
    Content type: Research Published on:

  14. The circadian clock governs a large variety of fundamentally important physiological processes in all three domains of life. Consequently, asynchrony in timekeeping mechanisms could give rise to cellular dysfu...

    Authors: Wai Hoong Chang and Alvina G. Lai
    Citation: Journal of Translational Medicine 2019 17:132
    Content type: Research Published on:

  15. Tumor hypoxia is associated with metastasis and resistance to chemotherapy and radiotherapy. Genes involved in oxygen-sensing are clinically relevant and have significant implications for prognosis. In this st...

    Authors: Wai Hoong Chang, Donall Forde and Alvina G. Lai
    Citation: Cancer Communications 2019 39:23
    Content type: Original article Published on: