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7 result(s) for 'author#"Rainer J. Klement"' within BMC

1. Application of Bayesian evidence synthesis to modelling the effect of ketogenic therapy on survival of high grade glioma patients

   Ketogenic therapy in the form of ketogenic diets or calorie restriction has been proposed as a metabolic treatment of high grade glioma (HGG) brain tumors based on mechanistic reasoning obtained mainly from an...

   Authors: Rainer J. Klement, Prasanta S. Bandyopadhyay, Colin E. Champ and Harald Walach

   Citation: Theoretical Biology and Medical Modelling 2018 15:12

   Content type: Research

   Published on: 20 August 2018

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2. Is there a role for carbohydrate restriction in the treatment and prevention of cancer?

   Over the last years, evidence has accumulated suggesting that by systematically reducing the amount of dietary carbohydrates (CHOs) one could suppress, or at least delay, the emergence of cancer, and that prol...

   Authors: Rainer J Klement and Ulrike Kämmerer

   Citation: Nutrition & Metabolism 2011 8:75

   Content type: Review

   Published on: 26 October 2011

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3. Impact of a ketogenic diet intervention during radiotherapy on body composition: III—final results of the KETOCOMP study for breast cancer patients

   Obesity and low muscle mass are associated with worse outcomes of breast cancer patients. We conducted a controlled trial to study the impact of a ketogenic diet (KD) based on natural foods versus an unspecifi...

   Authors: Rainer J. Klement, Colin E. Champ, Ulrike Kämmerer, Petra S. Koebrunner, Kelley Krage, Gabriele Schäfer, M. Weigel and Reinhart A. Sweeney

   Citation: Breast Cancer Research 2020 22:94

   Content type: Research article

   Published on: 20 August 2020

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4. Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation

   Ketogenic diets (KDs) or short-term fasting are popular trends amongst supportive approaches for cancer patients. Beta-hydroxybutyrate (3-OHB) is the main physiological ketone body, whose concentration can rea...

   Authors: Catharina Bartmann, Sudha R. Janaki Raman, Jessica Flöter, Almut Schulze, Katrin Bahlke, Jana Willingstorfer, Maria Strunz, Achim Wöckel, Rainer J. Klement, Michaela Kapp, Cholpon S. Djuzenova, Christoph Otto and Ulrike Kämmerer

   Citation: Cancer & Metabolism 2018 6:8

   Content type: Research

   Published on: 11 June 2018

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5. Accelerated hyperfractionated radiochemotherapy with temozolomide is equivalent to normofractionated radiochemotherapy in a retrospective analysis of patients with glioblastoma

   Current standard of treatment for newly diagnosed patients with glioblastoma (GBM) is surgical resection with adjuvant normofractionated radiotherapy (NFRT) combined with temozolomide (TMZ) chemotherapy. Hyper...

   Authors: Victor Lewitzki, Rainer J. Klement, Rebekka Kosmala, Dominik Lisowski, Michael Flentje and Bülent Polat

   Citation: Radiation Oncology 2019 14:227

   Content type: Research

   Published on: 12 December 2019

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6. Impact of a ketogenic diet intervention during radiotherapy on body composition: I. Initial clinical experience with six prospectively studied patients

   Based on promising preclinical data, ketogenic diets (KDs) have been proposed as supplementary measures for cancer patients undergoing standard-of-care therapy. However, data is still scarce on the tolerabilit...

   Authors: Rainer J. Klement and Reinhart A. Sweeney

   Citation: BMC Research Notes 2016 9:143

   Content type: Research

   Published on: 5 March 2016

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7. The impact of local control on overall survival after stereotactic body radiotherapy for liver and lung metastases from colorectal cancer: a combined analysis of 388 patients with 500 metastases

   The aim of this analysis was to model the effect of local control (LC) on overall survival (OS) in patients treated with stereotactic body radiotherapy (SBRT) for liver or lung metastases from colorectal cancer.

   Authors: Rainer J. Klement, N. Abbasi-Senger, S. Adebahr, H. Alheid, M. Allgaeuer, G. Becker, O. Blanck, J. Boda-Heggemann, T. Brunner, M. Duma, M. J. Eble, I. Ernst, S. Gerum, D. Habermehl, P. Hass, C. Henkenberens…

   Citation: BMC Cancer 2019 19:173

   Content type: Research article

   Published on: 26 February 2019

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