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13 result(s) for 'author#"Paul Cockwell"' within BMC

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  1. The development of serum immunoassays for the measurement of immunoglobulin free light chains has led to a paradigm shift in the diagnosis, assessment and monitoring of patients with plasma cell dyscrasias. Th...

    Authors: Colin A Hutchison, Paul Cockwell and Mark Cook

    Citation: BMC Clinical Pathology 2012 12:12

    Content type: Technical advance

    Published on:

  2. Calciphylaxis occurring after kidney transplantation is rare and rarely reported. It results in chronic non-healing wounds and is associated with a poor prognosis and is often fatal. We present a case of proxi...

    Authors: Rajesh Hanvesakul, Michael A Silva, Rahul Hejmadi, Steve Mellor, Andrew R Ready, Paul Cockwell and Nicholas Inston

    Citation: Journal of Medical Case Reports 2009 3:9297

    Content type: Case report

    Published on:

  3. Monoclonal free light chains (FLCs) frequently cause rapidly progressive renal failure in patients with multiple myeloma. Immunoassays which provide quantitative measurement of FLCs in serum, have now been ado...

    Authors: Colin A Hutchison, Tim Plant, Mark Drayson, Paul Cockwell, Melpomeni Kountouri, Kolitha Basnayake, Stephen Harding, Arthur R Bradwell and Graham Mead

    Citation: BMC Nephrology 2008 9:11

    Content type: Research article

    Published on:

  4. Acute renal failure in multiple myeloma is most frequently caused by cast nephropathy, when excess monoclonal free light chains co-precipitate with Tamm-Horsfall protein in the distal nephron, causing tubular ...

    Authors: Kolitha Basnayake, Colin Hutchison, Dia Kamel, Michael Sheaff, Neil Ashman, Mark Cook, Heather Oakervee, Arthur Bradwell and Paul Cockwell

    Citation: Journal of Medical Case Reports 2008 2:380

    Content type: Case report

    Published on:

  5. Renal impairment (RI) is common in multiple myeloma (MM) and is associated with poor survival. This study reports the associations between renal function and disease characteristics including serum free light ...

    Authors: Punit Yadav, Paul Cockwell, Mark Cook, Jennifer Pinney, Hannah Giles, Yu Sandar Aung, David Cairns, Roger G. Owen, Faith E. Davies, Graham H. Jackson, J. Anthony Child, Gareth J. Morgan and Mark T. Drayson

    Citation: BMC Nephrology 2018 19:178

    Content type: Research article

    Published on:

  6. Renal failure is a frequent complication of multiple myeloma and when severe is associated with a greatly increased morbidity and mortality. The principal cause of severe renal failure is cast nephropathy, a d...

    Authors: Colin A Hutchison, Mark Cook, Nils Heyne, Katja Weisel, Lucinda Billingham, Arthur Bradwell and Paul Cockwell

    Citation: Trials 2008 9:55

    Content type: Study protocol

    Published on:

  7. The association of several comorbidities, including diabetes mellitus, hypertension, cardiovascular disease, heart failure and chronic kidney or liver disease, with acute kidney injury (AKI) is well establishe...

    Authors: Charalampos Loutradis, Luke Pickup, Jonathan P. Law, Indranil Dasgupta, Jonathan N. Townend, Paul Cockwell, Adnan Sharif, Pantelis Sarafidis and Charles J. Ferro

    Citation: Biology of Sex Differences 2021 12:30

    Content type: Research

    Published on:

  8. Accurate blood pressure monitoring is critical for the management of chronic kidney disease, but changes in management in secondary care clinics may be based on a single blood pressure reading, with a subseque...

    Authors: Shona Brothwell, Mary Dutton, Charles Ferro, Stephanie Stringer and Paul Cockwell

    Citation: BMC Nephrology 2013 14:218

    Content type: Research article

    Published on:

  9. Chronic kidney disease (CKD) affects up to 16% of the adult population and is associated with significant morbidity and mortality. People at highest risk from progressive CKD are defined by a sustained decline...

    Authors: Stephanie Stringer, Praveen Sharma, Mary Dutton, Mark Jesky, Khai Ng, Okdeep Kaur, Iain Chapple, Thomas Dietrich, Charles Ferro and Paul Cockwell

    Citation: BMC Nephrology 2013 14:95

    Content type: Study protocol

    Published on:

  10. Uncertainty exists regarding the optimal method to estimate glomerular filtration rate (GFR) for disease detection and monitoring. Widely used GFR estimates have not been validated in British ethnic minority p...

    Authors: Edmund J Lamb, Elizabeth A Brettell, Paul Cockwell, Neil Dalton, Jon J Deeks, Kevin Harris, Tracy Higgins, Philip A Kalra, Kamlesh Khunti, Fiona Loud, Ryan S Ottridge, Claire C Sharpe, Alice J Sitch, Paul E Stevens, Andrew J Sutton and Maarten W Taal

    Citation: BMC Nephrology 2014 15:13

    Content type: Study protocol

    Published on:

  11. Patients with chronic kidney disease (CKD) exhibit increased morbidity and mortality which is associated with an increased systemic inflammatory burden. Identifying and managing comorbid diseases that contribu...

    Authors: Praveen Sharma, Paul Cockwell, Thomas Dietrich, Charles Ferro, Natalie Ives and Iain L. C. Chapple

    Citation: Trials 2017 18:535

    Content type: Study protocol

    Published on:

  13. The ANCA-associated vasculitides (AAV) are systemic autoimmune inflammatory disorders characterised by necrotising inflammation affecting small to medium-sized blood vessels. Despite improvements in survival, ...

    Authors: Dimitrios Chanouzas, Lovesh Dyall, Peter Nightingale, Charles Ferro, Paul Moss, Matthew David Morgan and Lorraine Harper

    Citation: Trials 2016 17:338

    Content type: Study protocol

    Published on: