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10 result(s) for 'author#"David J. Abraham"' within BMC

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  1. The mechanism underlying the ability of fibroblasts to contract a collagen gel matrix is largely unknown. Fibroblasts from scarred (lesional) areas of patients with the fibrotic disease scleroderma show enhanc...

    Authors: Yunliang Chen, Andrew Leask, David J Abraham, Laura Kennedy, Xu Shi-wen, Christopher P Denton, Carol M Black, Liaquat S Verjee and Mark Eastwood

    Citation: Fibrogenesis & Tissue Repair 2011 4:9

    Content type: Research

    Published on:

    The Erratum to this article has been published in Fibrogenesis & Tissue Repair 2015 8:4

  2. Authors: Yunliang Chen, Andrew Leask, David J Abraham, Laura Kennedy, Xu Shi-wen, Christopher P Denton, Carol M Black, Liaquat S Verjee and Mark Eastwood

    Citation: Fibrogenesis & Tissue Repair 2015 8:4

    Content type: Erratum

    Published on:

    The original article was published in Fibrogenesis & Tissue Repair 2011 4:9

  3. Authors: Matthew R McCann, Roxana Monemdjou, Parisa Ghassemi-Kakroodi, Hassan Fahmi, Gemma Perez, Shangxi Liu, Xu Shi-wen, Sunil K Parapuram, Fumiaki Kojima, Christopher P Denton, David J Abraham, Johanne Martel-Pelletier, Leslie J Crofford, Andrew Leask and Mohit Kapoor

    Citation: Arthritis Research & Therapy 2011 13:402

    Content type: Erratum

    Published on:

    The original article was published in Arthritis Research & Therapy 2011 13:R6

  4. Interstitial lung disease is a major cause of morbidity and mortality in systemic sclerosis (SSc), with insufficiently effective treatment options. Progression of pulmonary fibrosis involves expanding populati...

    Authors: Gisela E Lindahl, Carmel JW Stock, Xu Shi-Wen, Patricia Leoni, Piersante Sestini, Sarah L Howat, George Bou-Gharios, Andrew G Nicholson, Christopher P Denton, Jan C Grutters, Toby M Maher, Athol U Wells, David J Abraham and Elisabetta A Renzoni

    Citation: Respiratory Research 2013 14:80

    Content type: Research

    Published on:

  5. The TβRII∆k-fib transgenic (TG) mouse model of scleroderma replicates key fibrotic and vasculopathic complications of systemic sclerosis through fibroblast-directed upregulation of TGFβ signalling. We have exa...

    Authors: Emma Derrett-Smith, Kristina E. N. Clark, Xu Shiwen, David J. Abraham, Rachel K. Hoyles, Olivier Lacombe, Pierre Broqua, Jean Louis Junien, Irena Konstantinova, Voon H. Ong and Christopher P. Denton

    Citation: Arthritis Research & Therapy 2021 23:234

    Content type: Research article

    Published on:

  6. The mechanisms by which microvascular damage leads to dermal fibrosis in diffuse cutaneous systemic sclerosis (dcSSc) are unclear. We hypothesized that microvascular pericytes constitute a cellular link betwee...

    Authors: Vineeth S Rajkumar, Kevin Howell, Katalin Csiszar, Christopher P Denton, Carol M Black and David J Abraham

    Citation: Arthritis Research & Therapy 2005 7:R1113

    Content type: Research article

    Published on:

  7. Microsomal prostaglandin E2 synthase-1 (mPGES-1) is an inducible enzyme that acts downstream of cyclooxygenase (COX) to specifically catalyze the conversion of prostaglandin (PG) H2 to PGE2. mPGES-1 plays a key r...

    Authors: Matthew R McCann, Roxana Monemdjou, Parisa Ghassemi-Kakroodi, Hassan Fahmi, Gemma Perez, Shangxi Liu, Xu Shi-wen, Sunil K Parapuram, Fumiaki Kojima, Christopher P Denton, David J Abraham, Johanne Martel-Pelletier, Leslie J Crofford, Andrew Leask and Mohit Kapoor

    Citation: Arthritis Research & Therapy 2011 13:R6

    Content type: Research article

    Published on:

    The Erratum to this article has been published in Arthritis Research & Therapy 2011 13:402

  8. Transforming growth factor beta (TGFβ), a multifunctional cytokine, plays a crucial role in the accumulation of extracellular matrix components in lung fibrosis, where lung fibroblasts are considered to play a...

    Authors: Elisabetta A Renzoni, David J Abraham, Sarah Howat, Xu Shi-Wen, Piersante Sestini, George Bou-Gharios, Athol U Wells, Srihari Veeraraghavan, Andrew G Nicholson, Christopher P Denton, Andrew Leask, Jeremy D Pearson, Carol M Black, Kenneth I Welsh and Roland M du Bois

    Citation: Respiratory Research 2004 5:24

    Content type: Research

    Published on:

  9. Systemic sclerosis (SSc; scleroderma) is an uncommon autoimmune rheumatic disease characterised by autoimmunity, vasculopathy and fibrosis. Gene expression profiling distinguishes scleroderma from normal skin,...

    Authors: Emma C. Derrett-Smith, Viktor Martyanov, Cecilia B. Chighizola, Pia Moinzadeh, Corrado Campochiaro, Korsa Khan, Tammara A. Wood, Pier Luigi Meroni, David J. Abraham, Voon H. Ong, Robert Lafyatis, Michael L. Whitfield and Christopher P. Denton

    Citation: Arthritis Research & Therapy 2017 19:156

    Content type: Research article

    Published on:

  10. Clinical diversity in systemic sclerosis (SSc) reflects multifaceted pathogenesis and the effect of key growth factors or cytokines operating within a disease-specific microenvironment. Dermal interstitial flu...

    Authors: Kristina EN Clark, Henry Lopez, Bahja Ahmed Abdi, Sandra G Guerra, Xu Shiwen, Korsa Khan, Oseme Etomi, George R Martin, David J Abraham, Christopher P Denton and Richard J Stratton

    Citation: Arthritis Research & Therapy 2015 17:73

    Content type: Research article

    Published on: