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13 result(s) for 'author#"Conrad E Johanson"' within BMC

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  2. The Kearns-Sayre syndrome is a mitochondrial disorder (generally due to mitochondrial DNA deletions) that causes ophthalmoplegia, retinopathy, ataxia and brain abnormalities such as leukoencephalopathy. In thi...

    Authors: Reynold Spector and Conrad E Johanson

    Citation: Cerebrospinal Fluid Research 2010 7:14

    Content type: Commentary

    Published on:

  3. Amyloid accumulation in the brain parenchyma is a hallmark of Alzheimer's disease (AD) and is seen in normal aging. Alterations in cerebrospinal fluid (CSF) dynamics are also associated with normal aging and A...

    Authors: Catherine Chiu, Miles C Miller, Ilias N Caralopoulos, Michael S Worden, Thomas Brinker, Zachary N Gordon, Conrad E Johanson and Gerald D Silverberg

    Citation: Fluids and Barriers of the CNS 2012 9:3

    Content type: Research

    Published on:

  4. This review integrates eight aspects of cerebrospinal fluid (CSF) circulatory dynamics: formation rate, pressure, flow, volume, turnover rate, composition, recycling and reabsorption. Novel ways to modulate CS...

    Authors: Conrad E Johanson, John A Duncan III, Petra M Klinge, Thomas Brinker, Edward G Stopa and Gerald D Silverberg

    Citation: Cerebrospinal Fluid Research 2008 5:10

    Content type: Review

    Published on:

  5. Previous studies in aging animals have shown that amyloid-beta protein (Aβ) accumulates and its transporters, low-density lipoprotein receptor-related protein-1 (LRP-1) and the receptor for advanced glycation ...

    Authors: Kelley E Deren, Jennifer Forsyth, Osama Abdullah, Edward W Hsu, Petra M Klinge, Gerald D Silverberg, Conrad E Johanson and James P McAllister II

    Citation: Cerebrospinal Fluid Research 2009 6:4

    Content type: Research

    Published on:

  6. Adult rat hypothalamo-pituitary axis and choroid plexus are rich in basic fibroblast growth factor (FGF2) which likely has a role in fluid homeostasis. Towards this end, we characterized the distribution and m...

    Authors: Ana M Gonzalez, William M Taylor, Conrad E Johanson, Joan C King, Wendy E Leadbeater, Edward G Stopa and Andrew Baird

    Citation: Cerebrospinal Fluid Research 2010 7:13

    Content type: Research

    Published on:

  7. The content and composition of cerebrospinal fluid (CSF) is determined in large part by the choroid plexus (CP) and specifically, a specialized epithelial cell (CPe) layer that responds to, synthesizes, and tr...

    Authors: Ana Maria Gonzalez, Sonia Podvin, Shuh-Yow Lin, Miles C Miller, Hannah Botfield, Wendy E Leadbeater, Andrew Roberton, Xitong Dang, Stuart E Knowling, Elena Cardenas-Galindo, John E Donahue, Edward G Stopa, Conrad E Johanson, Raul Coimbra, Brian P Eliceiri and Andrew Baird

    Citation: Fluids and Barriers of the CNS 2011 8:6

    Content type: Research

    Published on:

  8. Age is the major risk factor for many neurodegenerative diseases, including Alzheimer's disease (AD). There is an accumulation of amyloid-beta peptides (Aβ) in both the AD brain and the normal aging brain. Cle...

    Authors: Crissey L Pascale, Miles C Miller, Catherine Chiu, Matthew Boylan, Ilias N Caralopoulos, Liliana Gonzalez, Conrad E Johanson and Gerald D Silverberg

    Citation: Fluids and Barriers of the CNS 2011 8:21

    Content type: Research

    Published on:

  11. Because the choroid plexus (CP) is uniquely suited to control the composition of cerebrospinal fluid (CSF), there may be therapeutic benefits to increasing the levels of biologically active proteins in CSF to ...

    Authors: Ana Maria Gonzalez, Wendy E Leadbeater, Michael Burg, Karen Sims, Tetsuya Terasaki, Conrad E Johanson, Edward G Stopa, Brian P Eliceiri and Andrew Baird

    Citation: BMC Neuroscience 2011 12:4

    Content type: Research article

    Published on:

  12. The roles of the choroid plexus (CP) and cerebrospinal fluid (CSF) production have drawn increasing attention in Alzheimer’s disease (AD) research. Specifically, studies document markedly decreased CSF product...

    Authors: Shawn Kant, Edward G. Stopa, Conrad E. Johanson, Andrew Baird and Gerald D. Silverberg

    Citation: Fluids and Barriers of the CNS 2018 15:34

    Content type: Research

    Published on:

  13. In Alzheimer’s disease, there are striking changes in CSF composition that relate to altered choroid plexus (CP) function. Studying CP tissue gene expression at the blood–cerebrospinal fluid barrier could prov...

    Authors: Edward G. Stopa, Keith Q. Tanis, Miles C. Miller, Elena V. Nikonova, Alexei A. Podtelezhnikov, Eva M. Finney, David J. Stone, Luiz M. Camargo, Lisan Parker, Ajay Verma, Andrew Baird, John E. Donahue, Tara Torabi, Brian P. Eliceiri, Gerald D. Silverberg and Conrad E. Johanson

    Citation: Fluids and Barriers of the CNS 2018 15:18

    Content type: Research

    Published on: