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9 result(s) for 'author#"Christoph Otto"' within BMC

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  1. Among the most prominent metabolic alterations in cancer cells are the increase in glucose consumption and the conversion of glucose to lactic acid via the reduction of pyruvate even in the presence of oxygen....

    Authors: Christoph Otto, Ulrike Kaemmerer, Bertram Illert, Bettina Muehling, Nadja Pfetzer, Rainer Wittig, Hans Ullrich Voelker, Arnulf Thiede and Johannes F Coy

    Citation: BMC Cancer 2008 8:122

    Content type: Research article

    Published on:

  2. Investigation of the expression of an intestinal stem cell marker in esophageal adenocarcinomas (EAC) with and without Barrett's Esophagus (BE), with respect to a cancer stem cell (CSC) hypothesis.

    Authors: Burkhard HA von Rahden, Stefan Kircher, Maria Lazariotou, Christoph Reiber, Luisa Stuermer, Christoph Otto, Christoph T Germer and Martin Grimm

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:23

    Content type: Research

    Published on:

  3. Ascorbic acid demonstrates a cytotoxic effect by generating hydrogen peroxide, a reactive oxygen species (ROS) involved in oxidative cell stress. A panel of eleven human cancer cell lines, glioblastoma and car...

    Authors: Christoph Klingelhoeffer, Ulrike Kämmerer, Monika Koospal, Bettina Mühling, Manuela Schneider, Michaela Kapp, Alexander Kübler, Christoph-Thomas Germer and Christoph Otto

    Citation: BMC Complementary and Alternative Medicine 2012 12:61

    Content type: Research article

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  4. Unlike mouse immature bone marrow (BM)-derived dendritic cells (DC), rat immature BMDC have not been thoroughly characterised in vitro for the mechanisms underlying their suppressive effect. To better characteris...

    Authors: George Tiurbe, Anja Matuschek, Ulrike Kämmerer, Manuela Schneider, Arnulf Thiede, Karin Ulrichs and Christoph Otto

    Citation: BMC Research Notes 2009 2:12

    Content type: Short Report

    Published on:

  5. Esophageal adenocarcinomas (EACs) arise due to gastroesophageal reflux, with Barrett's esophagus (BE) regarded as precancerous lesion. Matrix metalloproteinases (MMPs) might play a role during the multistep ca...

    Authors: Martin Grimm, Maria Lazariotou, Stefan Kircher, Luisa Stuermer, Christoph Reiber, Andreas Höfelmayr, Stefan Gattenlöhner, Christoph Otto, Christoph T Germer and Burkhard HA von Rahden

    Citation: Journal of Translational Medicine 2010 8:99

    Content type: Research

    Published on:

  6. The development of new therapeutic strategies for treatment of metastasized colorectal carcinoma requires biologically relevant and adequate animal models that generate both reproducible metastasis and the dis...

    Authors: Andreas Thalheimer, Christoph Otto, Marco Bueter, Bertram Illert, Stefan Gattenlohner, Martin Gasser, Detlef Meyer, Martin Fein, Christoph T Germer and Ana M Waaga-Gasser

    Citation: BMC Cancer 2009 9:29

    Content type: Research article

    Published on:

  7. Ketogenic diets (KDs) or short-term fasting are popular trends amongst supportive approaches for cancer patients. Beta-hydroxybutyrate (3-OHB) is the main physiological ketone body, whose concentration can rea...

    Authors: Catharina Bartmann, Sudha R. Janaki Raman, Jessica Flöter, Almut Schulze, Katrin Bahlke, Jana Willingstorfer, Maria Strunz, Achim Wöckel, Rainer J. Klement, Michaela Kapp, Cholpon S. Djuzenova, Christoph Otto and Ulrike Kämmerer

    Citation: Cancer & Metabolism 2018 6:8

    Content type: Research

    Published on:

  8. Fermented wheat germ extract (FWGE) sold under the trade name Avemar exhibits anticancer activity in vitro and in vivo. Its mechanisms of action are divided into antiproliferative and antimetabolic effects. It...

    Authors: Christoph Otto, Theresa Hahlbrock, Kilian Eich, Ferdi Karaaslan, Constantin Jürgens, Christoph-Thomas Germer, Armin Wiegering and Ulrike Kämmerer

    Citation: BMC Complementary and Alternative Medicine 2016 16:160

    Content type: Research article

    Published on:

  9. Overexpression of transketolase-like 1 protein TKTL1 in cancer cells has been reported to correlate with enhanced glycolysis and lactic acid production. Furthermore, enhanced TKTL1 expression was put into cont...

    Authors: Ulrike Kämmerer, Olivier Gires, Nadja Pfetzer, Armin Wiegering, Rainer Johannes Klement and Christoph Otto

    Citation: BMC Cancer 2015 15:2

    Content type: Research article

    Published on: