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7 result(s) for 'author#"Cholpon S. Djuzenova"' within BMC

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  1. Phosphorylated histone H2AX, also known as γH2AX, forms μm-sized nuclear foci at the sites of DNA double-strand breaks (DSBs) induced by ionizing radiation and other agents. Due to their specificity and sensit...

    Authors: Simon Memmel, Dmitri Sisario, Heiko Zimmermann, Markus Sauer, Vladimir L. Sukhorukov, Cholpon S. Djuzenova and Michael Flentje

    Citation: BMC Bioinformatics 2020 21:27

    Content type: Methodology article

    Published on:

  2. High expression of constitutive histone γ-H2AX, a sensitive marker of DNA damage, might be indicative of defective DNA repair pathway or genomic instability. 53BP1 (p53-binding protein 1) is a conserved checkp...

    Authors: Cholpon S Djuzenova, Ines Elsner, Astrid Katzer, Eike Worschech, Luitpold V Distel, Michael Flentje and Bülent Polat

    Citation: Radiation Oncology 2013 8:98

    Content type: Research

    Published on:

  3. Ketogenic diets (KDs) or short-term fasting are popular trends amongst supportive approaches for cancer patients. Beta-hydroxybutyrate (3-OHB) is the main physiological ketone body, whose concentration can rea...

    Authors: Catharina Bartmann, Sudha R. Janaki Raman, Jessica Flöter, Almut Schulze, Katrin Bahlke, Jana Willingstorfer, Maria Strunz, Achim Wöckel, Rainer J. Klement, Michaela Kapp, Cholpon S. Djuzenova, Christoph Otto and Ulrike Kämmerer

    Citation: Cancer & Metabolism 2018 6:8

    Content type: Research

    Published on:

  4. In recent years attention has focused on γH2AX as a very sensitive double strand break indicator. It has been suggested that γH2AX might be able to predict individual radiosensitivity. Our aim was to study the...

    Authors: Jana Kroeber, Barbara Wenger, Manuela Schwegler, Christoph Daniel, Manfred Schmidt, Cholpon S Djuzenova, Bülent Polat, Michael Flentje, Rainer Fietkau and Luitpold V Distel

    Citation: Radiation Oncology 2015 10:36

    Content type: Research

    Published on:

  5. The mitogen-activated protein kinases (MAPK) and the phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) pathways are intertwined on various levels and simultaneous inhibition reduces tum...

    Authors: Sebastian Kuger, Michael Flentje and Cholpon S. Djuzenova

    Citation: Radiation Oncology 2015 10:214

    Content type: Research

    Published on:

  6. Most tumor cells show aberrantly activated Akt which leads to increased cell survival and resistance to cancer radiotherapy. Therefore, targeting Akt can be a promising strategy for radiosensitization. Here, w...

    Authors: Cholpon S. Djuzenova, Vanessa Fiedler, Simon Memmel, Astrid Katzer, Dmitri Sisario, Philippa K. Brosch, Alexander Göhrung, Svenja Frister, Heiko Zimmermann, Michael Flentje and Vladimir L. Sukhorukov

    Citation: BMC Cancer 2019 19:299

    Content type: Research article

    Published on:

  7. The prognostic value of histone γ-H2AX and 53BP1 proteins to predict the radiotherapy (RT) outcome of patients with rectal carcinoma (RC) was evaluated in a prospective study. High expression of the constituti...

    Authors: Cholpon S. Djuzenova, Marcus Zimmermann, Astrid Katzer, Vanessa Fiedler, Luitpold V. Distel, Martin Gasser, Anna-Maria Waaga-Gasser, Michael Flentje and Bülent Polat

    Citation: BMC Cancer 2015 15:856

    Content type: Research article

    Published on: