MHC-I genotype and tumor mutational burden predict response to immunotherapy
Immune checkpoint blockade (ICB) with antibodies inhibiting cytotoxic T lymphocyte-associated protein-4 (CTLA-4) and programmed cell death protein-1 (PD-1) (or its ligand (PD-L1)) can stimulate immune response...
Citation: Genome Medicine 2020 12:45