Microbiology and Infectious Diseases Gateway

Welcome to BioMed Central's Microbiology and Infectious Diseases Gateway. This gateway highlights the latest articles we have published in the microbiology and infectious diseases fields.


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  • Image attributed to: istock

    Ensuring safe medical apps

    Widely available apps to aid patient healthcare are methodologically weak and insecure; Paul Wicks and Emil Chiauzzi comment on these findings, discussing ways to ensure app innovation while prioritizing patient safety.

    BMC Medicine 2015, 13:205
  • Image attributed to: Wang et al., BMC Medicine

    Gene model predicts survival in CRPC

    A novel four-gene model based on blood mRNA expression patterns predicts survival in patients with castration-resistant prostate cancer (CRPC), so could be used as a minimally invasive approach to estimate prognosis in CRPC.

    BMC Medicine 2015, 13:201
  • Image attributed to: BioWardrobe


    A platform allowing users to store, visualize and analyze epigenomics and transcriptomics data using a biologist-friendly web interface, without the need for programming expertise.

    Genome Biology 2015, 16:158
  • OrthoFinder

    Solving fundamental biases in whole genome comparisons dramatically improves accuracy of orthogroup inference

    Genome Biology 2015, 16:157
  • Image attributed to: Sonnenblick et al., BMC Medicine

    pSTAT3 associated with trastuzumab resistance

    Expression of a phosphorylated STAT3 (pSTAT3)-associated gene signature is linked to trastuzumab resistance in HER2-positive breast cancer, suggesting that agents targeting the STAT3 pathway could help overcome resistance in the clinical setting.

    BMC Medicine 2015, 13:177
  • Read length cost-benefit

    An analysis finds that increasing the read length for RNA-seq studies does not improve ability to detect differential expression

    Genome Biology 2015, 16:131
  • Breast cancer-stroma interactions

    A systems level analysis of epithelial-stromal interactions in invasive breast cancer reveals the co-expression self-loops

    Genome Biology 2015, 16:128
  • Ultra-large alignments

    UPP is a method for ultra-large multiple sequence alignments using phylogeny-aware profiles, based on an ensemble of hidden Markov models

    Genome Biology 2015, 16:124
  • DNMT1-related methylation patterns

    DNMT1-dependent and –independent methylation patterns play distinct roles in mouse embryonic stem cell genome stability and transcriptional regulation

    Genome Biology 2015, 16:115
  • 3D chromatin domains

    An analysis integrating chromatin information and Hi-C data reveals features associated with topologically associating domains and nuclear compartments

    Genome Biology 2015, 16:110