Skip to main content

Durability Monitoring of Long-lasting Insecticidal Nets: Results and Learning from the VectorWorks Project

In spite of increasing vector resistance against pyrethroid insecticides and the acknowledged need to address residual transmission, insecticide treated nets remain the core element of malaria vector control in most endemic countries.

This success was possible by the introduction of the long-lasting insecticidal net (LLIN) technology some 20 years ago and the commitment of governments and donors to provide huge numbers of free LLIN to achieve and sustain universal coverage with LLIN. While the need to monitor the quality and field performance of LLIN products with respect to physical and insecticidal durability has long been established, results from operations research has at times been inconsistent or even misleading due to the lack of a comprehensive and standardized methodology for the physical durability of nets. This has changed with the release in 2013 of WHO guidance for estimating LLIN physical durability using a single, standardized metric that allows comparison of results between countries and at different time points.

The VectorWorks project has been monitoring LLIN durability as part of the U.S. President’s Malaria Initiative in seven countries applying a standardized methodology based on the latest recommendations from WHO and building in-country capacity for future durability monitoring activities. Different brands of LLIN were followed up in prospective cohort studies for up to three years looking at two principal scenarios: either comparing two different brands of LLIN in very similar ecological and socio-behavioral settings, or comparing the same brand of LLIN in different parts of a country where varying durability performance is expected due to differences in environmental and/or cultural or behavioral differences.
The results from each country provide valuable information for the Malaria Control or Elimination Program management teams, but also allow significant learnings from cross-country comparisons and pooled data analysis.

This series comprehensively summarizes the work done within the VectorWorks project and is hoped to contribute to a better understanding of drivers of physical and insecticidal durability of LLIN.

Edited by: Joshua Yukich, Tulane University, USA

  1. Sleeping under an ITN reduces contact with mosquitoes through the combination of a physical barrier and an insecticidal effect, which reduces the incidence of malaria. The 2016–2020 Burkina Faso National Malar...

    Authors: Mahamadi Tassembedo, Soumaila Coulibaly and Boukary Ouedraogo
    Citation: Malaria Journal 2021 20:220
  2. Malaria during pregnancy and childhood is one of the major public health challenges globally. Its prevalence is huge in Africa, especially in sub-Saharan countries and Ethiopia. Insecticide-treated mosquito ne...

    Authors: Amlaku Nigusie Yirsaw, Resom Berhe Gebremariam, Wallelign Alemnew Getnet and Muhabaw Shumye Mihret
    Citation: Malaria Journal 2021 20:130
  3. Attempts have been made to link procurement of long-lasting insecticidal nets (LLIN) not only to the price but also the expected performance of the product. However, to date it has not been possible to identif...

    Authors: Albert Kilian, Emmanuel Obi, Paul Mansiangi, Ana Paula Abílio, Khamis Ameir Haji, Estelle Guillemois, Vera Chetty, Amy Wheldrake, Sean Blaufuss, Bolanje Olapeju, Stella Babalola, Stephen J. Russell and Hannah Koenker
    Citation: Malaria Journal 2021 20:29
  4. Physical durability of long-lasting-insecticidal nets (LLIN) is an important aspect of the effectiveness of LLIN as a malaria prevention tool, but there is limited data on performance across locations and prod...

    Authors: Albert Kilian, Emmanuel Obi, Paul Mansiangi, Ana Paula Abílio, Khamis Ameir Haji, Sean Blaufuss, Bolanle Olapeju, Stella Babalola and Hannah Koenker
    Citation: Malaria Journal 2021 20:26
  5. Long-lasting insecticidal nets (LLINs) are the primary malaria prevention and control intervention in many parts of sub-Saharan Africa. While LLINs are expected to last at least 3 years under normal use condit...

    Authors: Olivier Briet, Hannah Koenker, Laura Norris, Ryan Wiegand, Jodi Vanden Eng, Alex Thackeray, John Williamson, John E. Gimnig, Filomeno Fortes, Martin Akogbeto, Anges W. Yadouleton, Maurice Ombok, M. Nabie Bayoh, Themba Mzilahowa, Ana Paula Abílio, Samuel Mabunda…
    Citation: Malaria Journal 2020 19:310
  6. Malaria prevention with long-lasting insecticidal nets (LLINs) has seen a tremendous scale-up in sub-Saharan Africa in the last decade. To sustain this success, it is important to understand how long LLINs rem...

    Authors: Ana Paula Abílio, Emmanuel Obi, Hannah Koenker, Stella Babalola, Abuchahama Saifodine, Rose Zulliger, Isabel Swamidoss, Gabriel Ponce de Leon, Eunice Alfai, Sean Blaufuss, Bolanle Olapeju, Hunter Harig and Albert Kilian
    Citation: Malaria Journal 2020 19:209
  7. Anecdotal reports from DRC suggest that long-lasting insecticidal nets (LLIN) distributed through mass campaigns in DRC may not last the expected average three years. To provide the National Malaria Control Pr...

    Authors: Paul Mansiangi, Solange Umesumbu, Irène Etewa, Jacques Zandibeni, Nissi Bafwa, Sean Blaufuss, Bolanle Olapeju, Ferdinand Ntoya, Aboubacar Sadou, Seth Irish, Eric Mukomena, Lydie Kalindula, Francis Watsenga, Martin Akogbeto, Stella Babalola, Hannah Koenker…
    Citation: Malaria Journal 2020 19:189
  8. Malaria transmission in Zanzibar has dramatically reduced in recent years but vector control interventions such as long-lasting insecticidal nets (LLIN) must continue to reach malaria elimination. To achieve t...

    Authors: Khamis Ameir Haji, Bakari Omar Khatib, Emmanuel Obi, Kanuth Dimoso, Hannah Koenker, Stella Babalola, George Greer, Naomi Serbantez, Faiza Abbas, Abdullah Ali, Sean Blaufuss, Bolanle Olapeju and Albert Kilian
    Citation: Malaria Journal 2020 19:187
  9. Following guidance from the US President’s Malaria Initiative, durability monitoring of DawaPlus® 2.0 brand of long-lasting insecticidal net (LLIN) distributed during the 2015/16 mass campaign was set up in three...

    Authors: Emmanuel Obi, Festus Okoh, Sean Blaufuss, Bolanle Olapeju, Joel Akilah, Okefu Oyale Okoko, Abidemi Okechukwu, Mark Maire, Kehinda Popoola, Muhammad Abdullahi Yahaya, Chigozie Jesse Uneke, Samson Awolola, Olivier Pigeon, Stella Babalola, Hannah Koenker and Albert Kilian
    Citation: Malaria Journal 2020 19:124