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Call for papers - Treatment-resistant psychiatric disorders

Guest Editors

Luisella Bocchio-Chiavetto, PhD, eCampus University, IRCCS San Giovanni di Dio Research Centre, Italy
Ebenezer Oloyede, MPharm, PhD, University of Oxford, UK
Eromona Whiskey, BPharm, PhD, South London & Maudsley NHS Foundation Trust, King's College London, UK

Submission Status: Open   |   Submission Deadline: 6 January 2025

BMC Psychiatry seeks cutting-edge research on treatment-resistant psychiatric disorders, addressing the complexities of treatment resistance and its impact on mental health outcomes. We welcome submissions that explore the underlying mechanisms, challenges, and innovative approaches related to treatment-resistant mental illnesses, with the aim of advancing personalized treatment strategies and improving the well-being of individuals affected by these conditions.

New Content ItemThis Collection supports and amplifies research related to SDG 3: Good Health & Wellbeing.

Meet the Guest Editors

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Luisella Bocchio-Chiavetto, PhD, eCampus University, IRCCS San Giovanni di Dio Research Centre, Italy

Professor Luisella Bocchio-Chiavetto is a Full Professor of Experimental Biology in the Department of Theoretical and Applied Sciences at eCampus University and research collaborator at the Psychiatric Unit of IRCCS San Giovanni di Dio Research Centre. Her primary area of research includes the molecular basis of etiology and treatment response in major psychosis.

Her main fields have been the role of immune system modulators and neurotrophic factors in the pathogenesis and in the action mechanism of pharmacological and non-pharmacological therapies. More recently her studies are focused on the possible involvement of microRNAs and metabolic/immune alterations in mood disorders, first episode psychosis, and personality disorders as well as the identification of biomarkers for differential diagnosis and personalization of pharmacological and psychotherapeutic treatments. She also serves as an Editorial Board Member for BMC Psychiatry.

Ebenezer Oloyede, MPharm, PhD, University of Oxford, UK

Dr Ebenezer Oloyede is the Principal Pharmacist at the South London and Maudsley NHS Foundation Trust, and an honorary lecturer in the Institute of Psychiatry, Psychology & Neuroscience at King's College London. His clinical expertise is in the use of psychotropic medication in early intervention in psychosis, and his academic research focusses on epidemiology and population research in treatment-resistant psychosis. 


Eromona Whiskey, BPharm, PhD, South London & Maudsley NHS Foundation Trust, King's College London, UK

Dr Eromona Whiskey is a Consultant Mental Health Pharmacist at the South London and Maudsley NHS Foundation Trust and an Honorary Senior Lecturer in the Institute of Pharmaceutical Sciences at King's College London. He has more than 25 years’ experience in the pharmacotherapy of schizophrenia. Dr Whiskey is a member of the Expert Psychopharmacology Group of the National Psychosis Service at the South London & Maudsley NHS Foundation Trust and a former head of the National Psychotropic Medicines Information Service at the same institution. Dr Whiskey is a regular contributor to the highly influential Maudsley Prescribing Guidelines.  His main research interest is in psychopharmacology of refractory psychotic disorders, an area in which he has published widely.  He is a notable speaker at national and international psychopharmacology conferences. 

About the Collection

BMC Psychiatry welcomes submissions to our Collection on Treatment-resistant psychiatric disorders.

Treatment-resistant psychiatric disorders present a significant challenge in mental health care, as individuals with these conditions often do not respond to standard treatments, including medication and psychotherapy. This Collection gathers research on the complexities of treatment-resistant mental illnesses such as depression, anxiety, bipolar disorder, schizophrenia, and co-occurring conditions. We invite submissions that investigate the underlying mechanisms of treatment resistance as well as the impact of misdiagnosis, medication intolerance, and patient incompliance in the context of treatment-resistant psychiatric disorders.

It is important to continue advancing our collective understanding of treatment-resistant psychiatric disorders to improve patient outcomes and quality of life. Recent advances in this area have highlighted the need for personalized treatment approaches, considering individual variations in treatment response and the presence of co-occurring conditions. Additionally, research has emphasized the importance of addressing the underlying neurobiological mechanisms of treatment resistance and exploring innovative therapeutic modalities beyond traditional medication and therapy.

Topics of interest include, but are not limited to:

  • Mechanisms of treatment resistance in psychiatric disorders
  • Personalized treatment approaches for treatment-resistant mental illnesses
  • Innovative therapeutic modalities for treatment-resistant psychiatric disorders
  • Mechanisms of treatment resistance in specific psychiatric disorders (e.g., depression, anxiety, bipolar disorder, schizophrenia)
  • Impact of misdiagnosis and co-occurring conditions on treatment resistance
  • Innovative therapeutic modalities such as neuromodulation and digital interventions for treatment-resistant psychiatric disorders
  • Challenges associated with lack of patient compliance and strategies to improve adherence to treatment regimens

Image credit: Andrii Zastrozhnov /

There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Treatment-resistant psychiatric disorders" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.