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Travellers' malaria

Guest edited by Prof Patricia Schlagenhauf.

Travellers' malaria is an exciting topic. It is a field in flux with evolving options for chemoprophylaxis, self-diagnosis, self-treatment, risk/strategy analyses and surveillance. Ideologies vary and experts differ but debate is needed and can bring change. This series from Malaria Journal is a forum to bring together research papers, reviews, opinion papers and commentaries, and will hopefully stimulate debate.

View all collections published in Malaria Journal.

  1. Case report

    Severe delayed autoimmune haemolytic anaemia following artesunate administration in severe malaria: a case report

    Parenteral artesunate is recommended as first-line therapy for severe and complicated malaria. Although its efficacy has been proven, long-term safety profile is still under evaluation. Several cases of delaye...

    Loic Raffray, Marie-Catherine Receveur, Mathilde Beguet, Pierre Lauroua, Thierry Pistone and Denis Malvy

    Malaria Journal 2014 13:398

    Published on: 11 October 2014

  2. Research

    Risk factors for UK Plasmodium falciparum cases

    An increasing proportion of malaria cases diagnosed in UK residents with a history of travel to malaria endemic areas are due to Plasmodium falciparum.

    Amy Pinsent, Jonathan M Read, Jamie T Griffin, Valerie Smith, Peter W Gething, Azra C Ghani, Geoffrey Pasvol and T Déirdre Hollingsworth

    Malaria Journal 2014 13:298

    Published on: 4 August 2014

  3. Research

    Malaria in overseas labourers returning to China: an analysis of imported malaria in Jiangsu Province, 2001–2011

    While great success in malaria control has been achieved in China, imported malaria has become a major challenge in the context of malaria elimination. This retrospective study describes the epidemiological pr...

    Yaobao Liu, Michelle S Hsiang, Huayun Zhou, Weiming Wang, Yuanyuan Cao, Roly D Gosling, Jun Cao and Qi Gao

    Malaria Journal 2014 13:29

    Published on: 25 January 2014

  4. Case study

    A case report of transfusion-transmitted Plasmodium malariae from an asymptomatic non-immune traveller

    The incidence of transfusion-transmitted malaria is very low in non-endemic countries due to strict donor selection. The optimal strategy to mitigate the risk of transfusion-transmitted malaria in non-endemic ...

    Emmaline E Brouwer, Jaap J van Hellemond, Perry JJ van Genderen, Ed Slot, Lisette van Lieshout, Leo G Visser and Pieter J Wismans

    Malaria Journal 2013 12:439

    Published on: 5 December 2013

  5. Research

    Towards improved uptake of malaria chemoprophylaxis among West African travellers: identification of behavioural determinants

    Malaria is a potentially lethal illness for which preventive measures are not optimally used among all travellers. Travellers visiting friends and relatives in their country of origin (VFRs) are known to use c...

    Rosanne W Wieten, Janneke Harting, Pieter M Biemond, Martin P Grobusch and Michèle van Vugt

    Malaria Journal 2013 12:360

    Published on: 10 October 2013

  6. Research

    Importation of chloroquine-resistant Plasmodium falciparum by Guatemalan peacekeepers returning from the Democratic Republic of the Congo

    Malaria elimination is being pursued in five of seven Central American countries. Military personnel returning from peacekeeping missions in sub-Saharan Africa could import chloroquine-resistant Plasmodium falcip...

    Patricia C Juliao, Silvia Sosa, Luis D Gonzalez, Norma Padilla, Lucia Ortiz, Ira Goldman, Venkatachalam Udhayakumar and Kim A Lindblade

    Malaria Journal 2013 12:344

    Published on: 23 September 2013

  7. Research

    Accurate identification of the six human Plasmodium spp. causing imported malaria, including Plasmodium ovale wallikeri and Plasmodium knowlesi

    Accurate identification of Plasmodium infections in non-endemic countries is of critical importance with regard to the administration of a targeted therapy having a positive impact on patient health and managemen...

    Adriana Calderaro, Giovanna Piccolo, Chiara Gorrini, Sabina Rossi, Sara Montecchini, Maria Loretana Dell’Anna, Flora De Conto, Maria Cristina Medici, Carlo Chezzi and Maria Cristina Arcangeletti

    Malaria Journal 2013 12:321

    Published on: 13 September 2013

  8. Case report

    Plasmodium knowlesi and HIV co-infection in a German traveller to Thailand

    A case of Plasmodium knowlesi and HIV co-infection is reported in a German traveller returning from Thailand. The 54 year-old patient presented to the Institute of Tropical Medicine in Tübingen with a 11-day hist...

    Jonas Ehrhardt, Andreas Trein, Peter Gottfried Kremsner and Matthias Frank

    Malaria Journal 2013 12:283

    Published on: 13 August 2013

  9. Research

    Global malaria connectivity through air travel

    Air travel has expanded at an unprecedented rate and continues to do so. Its effects have been seen on malaria in rates of imported cases, local outbreaks in non-endemic areas and the global spread of drug res...

    Zhuojie Huang and Andrew J Tatem

    Malaria Journal 2013 12:269

    Published on: 2 August 2013

  10. Case report

    Hyposplenism revealed by Plasmodium malariae infection

    Hyposplenism, due to splenectomy, inherited red blood cell disorders or acquired conditions such as celiac disease, has an important impact on the severity of malaria, especially in non-immune patients. Conver...

    Benjamin Hommel, Alexandre Galloula, Anne Simon and Pierre Buffet

    Malaria Journal 2013 12:271

    Published on: 2 August 2013

  11. Research

    Severity of imported malaria: protective effect of taking malaria chemoprophylaxis

    Although chemoprophylaxis remains an important strategy for preventing malaria in travellers, its effectiveness may be compromised by lack of adherence. Inappropriate use of chemoprophylaxis is likely to incre...

    Klaske Vliegenthart-Jongbloed, Mariana de Mendonça Melo, Marlies E van Wolfswinkel, Rob Koelewijn, Jaap J van Hellemond and Perry JJ van Genderen

    Malaria Journal 2013 12:265

    Published on: 31 July 2013

  12. Research

    Environmental determinant of malaria cases among travellers

    Approximately 125 million travellers visit malaria-endemic countries annually and about 10,000 cases of malaria are reported after returning home. Due to the fact that malaria is insect vector transmitted, the...

    Gaëtan Texier, Vanessa Machault, Meili Barragti, Jean-Paul Boutin and Christophe Rogier

    Malaria Journal 2013 12:87

    Published on: 4 March 2013

  13. Research

    Gametocyte carriage in Plasmodium falciparum-infected travellers

    Gametocytes are the sexual stage of Plasmodium parasites. The determinants of gametocyte carriage have been studied extensively in endemic areas, but have rarely been explored in travellers with malaria. The inci...

    Catherine H Roberts, Margaret Armstrong, Ewa Zatyka, Samuel Boadi, Simon Warren, Peter L Chiodini, Colin J Sutherland and Tom Doherty

    Malaria Journal 2013 12:31

    Published on: 24 January 2013

  14. Research

    Safety of falciparum malaria diagnostic strategy based on rapid diagnostic tests in returning travellers and migrants: a retrospective study

    Rapid diagnostic tests for malaria (RDTs) allow accurate diagnosis and prompt treatment. Validation of their usefulness in travellers with fever was needed. The safety of a strategy to diagnose falciparum mala...

    Isabelle Anne Rossi, Valérie D’Acremont, Guy Prod’Hom and Blaise Genton

    Malaria Journal 2012 11:377

    Published on: 16 November 2012

  15. Research

    Real-time PCR diagnosis of Plasmodium vivax among blood donors

    When selecting blood donors in transfusion centres, one important problem is to identify, during screening, individuals with infectious diseases that can be transmitted by blood, such as malaria, especially wh...

    Sergio Batista-dos-Santos, Milene Raiol, Sidney Santos, Maristela G Cunha and Ândrea Ribeiro-dos-Santos

    Malaria Journal 2012 11:345

    Published on: 12 October 2012

  16. Review

    Management of imported malaria in Europe

    In this position paper, the European Society for Clinical Microbiology and Infectious Diseases, Study Group on Clinical Parasitology, summarizes main issues regarding the management of imported malaria cases. ...

    Helena H Askling, Fabrice Bruneel, Gerd Burchard, Francesco Castelli, Peter L Chiodini, Martin P Grobusch, Rogelio Lopez-Vélez, Margaret Paul, Eskild Petersen, Corneliu Popescu, Michael Ramharter and Patricia Schlagenhauf

    Malaria Journal 2012 11:328

    Published on: 17 September 2012

  17. Research

    Imported submicroscopic malaria in Madrid

    Submicroscopic malaria (SMM) can be defined as low-density infections of Plasmodium that are unlikely to be detected by conventional microscopy. Such submicroscopic infections only occasionally cause acute diseas...

    Germán Ramírez-Olivencia, José Miguel Rubio, Pablo Rivas, Mercedes Subirats, María Dolores Herrero, Mar Lago and Sabino Puente

    Malaria Journal 2012 11:324

    Published on: 12 September 2012

  18. Research

    The prognostic value of schizontaemia in imported Plasmodium falciparum malaria

    In Plasmodium falciparum infection, peripheral parasite counts do not always correlate well with the sequestered parasite burden. As erythrocytes parasitized with mature trophozoites and schizonts have a high ten...

    Marlies E van Wolfswinkel, Mariana de Mendonça Melo, Klaske Vliegenthart-Jongbloed, Rob Koelewijn, Jaap J van Hellemond and Perry J van Genderen

    Malaria Journal 2012 11:301

    Published on: 28 August 2012

  19. Research

    Automated red blood cell exchange as an adjunctive treatment for severe Plasmodium falciparum malaria at the Vienna General Hospital in Austria: a retrospective cohort study

    Severe falciparum malaria is associated with considerable rates of mortality, despite the administration of appropriate anti-malarial treatment. Since overall survival is associated with total parasite biomass...

    Lorenz Auer-Hackenberg, Thomas Staudinger, Andja Bojic, Gottfried Locker, Gerda C Leitner, Wolfgang Graninger, Stefan Winkler, Michael Ramharter and Nina Worel

    Malaria Journal 2012 11:158

    Published on: 7 May 2012

  20. Case report

    Imported Plasmodium falciparum malaria in HIV-infected patients: a report of two cases

    As HIV becomes a chronic infection, an increasing number of HIV-infected patients are travelling to malaria-endemic areas. Association of malaria with HIV/AIDS can be clinically severe. Severe falciparum malar...

    Silvia García-Bujalance, Carolina Navarro-San Francisco, José M Rubio, José R Arribas and Avelino Gutierrez

    Malaria Journal 2012 11:136

    Published on: 27 April 2012

  21. Research

    Treatment outcome of intravenous artesunate in patients with severe malaria in the Netherlands and Belgium

    Intravenous (IV) artesunate is the treatment of choice for severe malaria. In Europe, however, no GMP-manufactured product is available and treatment data in European travellers are scarce. Fortunately, artesu...

    Annemarie R Kreeftmeijer-Vegter, Perry J van Genderen, Leo G Visser, Wouter FW Bierman, Jan Clerinx, Cees KW van Veldhuizen and Peter J de Vries

    Malaria Journal 2012 11:102

    Published on: 31 March 2012

  22. Case study

    Costs analysis of the treatment of imported malaria

    To document the status of imported malaria infections and estimate the costs of treating of patients hospitalized with the diagnosis of imported malaria in the Slovak Republic during 2003 to 2008.

    Viera Svihrova, Maria Szilagyiova, Elena Novakova, Jan Svihra and Henrieta Hudeckova

    Malaria Journal 2012 11:1

    Published on: 2 January 2012

  23. Research

    Epidemiology of imported malaria among children and young adults in Barcelona (1990-2008)

    Increasing international travel and migration is producing changes in trends in infectious diseases, especially in children from many European cities. The objective of this study was to describe the epidemiolo...

    Mireia Garcia-Villarrubia, Juan-Pablo Millet, Patricia Garcia de Olalla, Joaquim Gascón, Victoria Fumadó, Jordi Gómez i Prat, Begoña Treviño, María-Jesús Pinazo, Juan Cabezos, José Muñoz, Francesc Zarzuela and Joan A Caylà

    Malaria Journal 2011 10:347

    Published on: 25 November 2011

  24. Methodology

    Malaria chemoprophylaxis recommendations for immigrants to Europe, visiting relatives and friends - a Delphi method study

    Numbers of travellers visiting friends and relatives (VFRs) from Europe to malaria endemic countries are increasing and include long-term and second generation immigrants, who represent the major burden of mal...

    Guido Calleri, Ron H Behrens, Matthias L Schmid, Federico Gobbi, Martin P Grobusch, Francesco Castelli, Joaquim Gascon, Zeno Bisoffi, Tomas Jelinek and Pietro Caramello

    Malaria Journal 2011 10:137

    Published on: 20 May 2011

  25. Editorial

    Travellers' malaria - 'one shoe does not fit all'

    Travellers' malaria is an exciting topic. It is a field in flux with evolving options for chemoprophylaxis, self-diagnosis, self-treatment, risk/strategy analyses and surveillance. Ideologies vary and experts ...

    Patricia Schlagenhauf and Marcel Hommel

    Malaria Journal 2011 10:129

    Published on: 17 May 2011