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Traumatic brain injury

Edited by Robert Stern

Chronic traumatic encephalopathy (CTE) has emerged as a significant public health problem, particularly among those in the military or athletes involved in contact sports such as boxing and football. It is believed that CTE is caused, in part, by exposure to repetitive brain trauma years or decades prior to the initial symptoms of neurodegenerative disease. This series, published in Alzheimer's Research & Therapy, addresses a range of topics pertinent to CTE, including up–to–date reviews of the neuropathology, neuropathogenesis, and clinical aspects of this tauopathy, including clinical presentation, neuroimaging, and diagnostic features. This series of articles has not been sponsored. All articles have undergone the journal’s standard peer review process overseen by the Series Editor, with final decisions made by the Editors in Chief. The Series Editor and Editors in Chief declare no competing interests.

  1. Review

    Clinical subtypes of chronic traumatic encephalopathy: literature review and proposed research diagnostic criteria for traumatic encephalopathy syndrome

    The long-term consequences of repetitive head impacts have been described since the early 20th century. Terms such as punch drunk and dementia pugilistica were first used to describe the clinical syndromes exp...

    Philip H Montenigro, Christine M Baugh, Daniel H Daneshvar, Jesse Mez, Andrew E Budson, Rhoda Au, Douglas I Katz, Robert C Cantu and Robert A Stern

    Alzheimer's Research & Therapy 2014 6:68

    Published on: 24 September 2014

  2. Review

    Neuroimaging in repetitive brain trauma

    Sports-related concussions are one of the major causes of mild traumatic brain injury. Although most patients recover completely within days to weeks, those who experience repetitive brain trauma (RBT) may be ...

    Thomas SC Ng, Alexander P Lin, Inga K Koerte, Ofer Pasternak, Huijun Liao, Sai Merugumala, Sylvain Bouix and Martha E Shenton

    Alzheimer's Research & Therapy 2014 6:10

    Published on: 24 February 2014

  3. Review

    What boxing tells us about repetitive head trauma and the brain

    Boxing and other combat sports may serve as a human model to study the effects of repetitive head trauma on brain structure and function. The initial description of what is now known as chronic traumatic encep...

    Charles Bernick and Sarah Banks

    Alzheimer's Research & Therapy 2013 5:23

    Published on: 4 June 2013