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Translating innovative biomedical research in disease treatments

Edited by Dr Wan-Wan Lin and Pan-Chyr Yang

A thematic series in Journal of Biomedical Science.

biomedical research 2 © ipopba / Getty Images / iStockThe Taiwan Bio-development Foundation (TBF) was established in 2014, contributed by a group of passionate entrepreneurs, who care about the development of biopharmaceutical research and biotech industry in Taiwan. The main purpose of the TBF is to cultivate talent in the field of biotechnology through establishing academic chairs, giving grants for long term and consistent support in research projects, providing training scholarships, organizing and sponsoring seminars and events, as well as aiding in the protection of intellectual property and technology transfer, etc. The initial focus is on the establishment of academic chairs.

Since 2014, TBF has totally named the recipients of 14 academic chairs. Each chair recipient will receive NT$25 million over a period of ten years. The chairs established by TBF is to encourage the talent of outstanding local scientists, make long-term investment in basic research and training, and promote the development of biotechnology industry in Taiwan. Annually, TBF holds a symposium and each chair reports to the public the progress of their research and poster discussion of all the students and postdoctoral fellows supported by TBF. Journal of Biomedical Science is glad to publish this thematic series for TBF chairs to contribute a review articles focusing on the advances of their special field in biomedical sciences.

As President Chi-Huey Wong, the founding TBF Chairman said that cultivating talent has a critical impact on the long-term development of the country, but it is hard to see the immediate returns of the investment in a short time. The donors have admirable foresight. We believe that the Foundation can have a major influence on the development of Taiwan’s biotech, aiding in the cultivation of talent needed both in basic research and industrial development, and in turn contributing to human health and welfare.

  1. Stem cell activity is subject to non-cell-autonomous regulation from the local microenvironment, or niche. In adaption to varying physiological conditions and the ever-changing external environment, the stem c...

    Authors: Chih-Lung Chen, Wen-Yen Huang, Eddy Hsi Chun Wang, Kang-Yu Tai and Sung-Jan Lin
    Citation: Journal of Biomedical Science 2020 27:43
  2. Vaccination is the most effective measure at preventing influenza virus infections. However, current seasonal influenza vaccines are only protective against closely matched circulating strains. Even with exten...

    Authors: Juine-Ruey Chen, Yo-Min Liu, Yung-Chieh Tseng and Che Ma
    Citation: Journal of Biomedical Science 2020 27:33
  3. It has been more than three decades since the first monoclonal antibody was approved by the United States Food and Drug Administration (US FDA) in 1986, and during this time, antibody engineering has dramatica...

    Authors: Ruei-Min Lu, Yu-Chyi Hwang, I-Ju Liu, Chi-Chiu Lee, Han-Zen Tsai, Hsin-Jung Li and Han-Chung Wu
    Citation: Journal of Biomedical Science 2020 27:1
  4. Engineering approaches were adopted for liver microsystems to recapitulate cell arrangements and culture microenvironments in vivo for sensitive, high-throughput and biomimetic drug screening. This review intr...

    Authors: Jyong-Huei Lee, Kuan-Lun Ho and Shih-Kang Fan
    Citation: Journal of Biomedical Science 2019 26:88
  5. The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for personalized cell therapies and ushered in new opportunities for regenerative medicine, disease modeling, iPSC-based d...

    Authors: Ching-Ying Huang, Chun-Lin Liu, Chien-Yu Ting, Yueh-Ting Chiu, Yu-Che Cheng, Martin W. Nicholson and Patrick C. H. Hsieh
    Citation: Journal of Biomedical Science 2019 26:87
  6. MAP4K3 (also named GLK) is a serine/threonine kinase, which belongs to the mammalian Ste20-like kinase family. At 22 years of age, GLK was initially cloned and identified as an upstream activator of the MAPK J...

    Authors: Huai-Chia Chuang and Tse-Hua Tan
    Citation: Journal of Biomedical Science 2019 26:82
  7. Autophagy is a major degradation pathway that utilizes lysosome hydrolases to degrade cellular constituents and is often induced under cellular stress conditions to restore cell homeostasis. Another prime degr...

    Authors: Ruey-Hwa Chen, Yu-Hsuan Chen and Tzu-Yu Huang
    Citation: Journal of Biomedical Science 2019 26:80
  8. Soft materials have been developed very rapidly in the biomedical field over the past 10 years because of advances in medical devices, cell therapy, and 3D printing for precision medicine. Smart polymers are o...

    Authors: Hung-Jin Huang, Yu-Liang Tsai, Shih-Ho Lin and Shan-hui Hsu
    Citation: Journal of Biomedical Science 2019 26:73
  9. Terminally differentiated B cell, the plasma cell, is the sole cell type capable of producing antibodies in our body. Over the past 30 years, the identification of many key molecules controlling B cell activat...

    Authors: Dong-Yan Tsai, Kuo-Hsuan Hung, Chia-Wei Chang and Kuo-I Lin
    Citation: Journal of Biomedical Science 2019 26:64