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Tissue Engineering and Regenerative Medicine

Edited by: Prof. Xiao-Bing Fu and Prof Xiao-Song Gu

Tissue Engineering and Regenerative Medicine are rapidly rising multidisciplinary fields that aim to restore, maintain, or enhance the functions of damaged tissues and organs. With the change of lifestyle and aggravating trend of aging population, the healthcare burden of degenerative diseases, tumors, tissue and organ defects, and other age-related diseases have been increasing. However, current therapeutic strategies either are limited by donor availability and immunological barriers or pertain to only a narrow range of conditions. Moreover, such conditions are unlikely to be completely cured by current standard treatments, and need novel therapeutic approaches. The research in this area is further boosted by rapid development of new medical technologies and the continuing expansion of medical research areas.

A mature therapeutic approach requires decades of research and practice, and tissue engineering/regenerative medicine are no exception. The major problem hindering the development of new therapeutics is insufficient translation of basic research findings to clinical practice. Basic and clinical scientists, as well as scientists working in the biotechnology and pharmaceutical industries, need to reach consensus before applying novel therapy clinically.

In this thematic series, we would like to better understand the Tissue Engineering and Regenerative Medicine.

This series was published in Military Medical Research.

  1. Wound healing, tissue repair and regenerative medicine are in great demand, and great achievements in these fields have been made. The traditional strategy of tissue repair and regeneration has focused on the ...

    Authors: Xiao-Bing Fu

    Citation: Military Medical Research 2021 8:2

    Content type: Commentary

    Published on:

  2. Compared with non-degradable materials, biodegradable biomaterials play an increasingly important role in the repairing of severe bone defects, and have attracted extensive attention from researchers. In the t...

    Authors: Shuai Wei, Jian-Xiong Ma, Lai Xu, Xiao-Song Gu and Xin-Long Ma

    Citation: Military Medical Research 2020 7:54

    Content type: Review

    Published on:

  3. Generation of neurons is essential in cell replacement therapy for neurodegenerative disorders like Parkinson’s disease. Several studies have reported the generation of dopaminergic (DA) neurons from mouse and...

    Authors: Hua Qin, An-Dong Zhao, Meng-Li Sun, Kui Ma and Xiao-Bing Fu

    Citation: Military Medical Research 2020 7:52

    Content type: Research

    Published on:

  4. Motor neuron degeneration or loss in the spinal cord is the characteristic phenotype of motor neuron diseases or spinal cord injuries. Being proliferative and located near neurons, astrocytes are considered id...

    Authors: An-Dong Zhao, Hua Qin, Meng-Li Sun, Kui Ma and Xiao-Bing Fu

    Citation: Military Medical Research 2020 7:42

    Content type: Research

    Published on:

    The Correction to this article has been published in Military Medical Research 2021 8:24

  5. Neuronal networks, especially those in the central nervous system (CNS), evolved to support extensive functional capabilities while ensuring stability. Several physiological “brakes” that maintain the stabilit...

    Authors: Palaniappan Ganesh Nagappan, Hong Chen and De-Yun Wang

    Citation: Military Medical Research 2020 7:30

    Content type: Review

    Published on: