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New technologies

  1. Review

    Fatigue in chronic inflammation - a link to pain pathways

    Fatigue is a frequent symptom in several inflammatory diseases, particularly in rheumatic diseases. Elements of disease activity and cognitive and behavior aspects have been reported as causes of fatigue in pa...

    Karine Louati and Francis Berenbaum

    Arthritis Research & Therapy 2015 17:254

    Published on: 5 October 2015

  2. Review

    Use of RNA sequencing to evaluate rheumatic disease patients

    Studying the factors that control gene expression is of substantial importance for rheumatic diseases with poorly understood etiopathogenesis. In the past, gene expression microarrays have been used to measure...

    Eugenia G Giannopoulou, Olivier Elemento and Lionel B Ivashkiv

    Arthritis Research & Therapy 2015 17:167

    Published on: 1 July 2015

  3. Review

    Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy

    The development of biomarkers for autoimmune diseases has been hampered by a lack of understanding of disease etiopathogenesis and of the mechanisms underlying the induction and maintenance of inflammation, wh...

    Nitya Nair, Henrik E Mei, Shih-Yu Chen, Matthew Hale, Garry P Nolan, Holden T Maecker, Mark Genovese, C Garrison Fathman and Chan C Whiting

    Arthritis Research & Therapy 2015 17:127

    Published on: 18 May 2015

  4. Review

    Polychromatic flow cytometry in evaluating rheumatic disease patients

    B cells are central players in multiple autoimmune rheumatic diseases as a result of the imbalance between pathogenic and protective B-cell functions, which are presumably mediated by distinct populations. Yet...

    Chungwen Wei, Scott Jenks and Iñaki Sanz

    Arthritis Research & Therapy 2015 17:46

    Published on: 5 March 2015

  5. Review

    T-cell metabolism in autoimmune disease

    Cancer cells have long been known to fuel their pathogenic growth habits by sustaining a high glycolytic flux, first described almost 90 years ago as the so-called Warburg effect. Immune cells utilize a simila...

    Zhen Yang, Eric L Matteson, Jörg J Goronzy and Cornelia M Weyand

    Arthritis Research & Therapy 2015 17:29

    Published on: 11 February 2015