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Stem cell engineering and regenerative medicine

  1. Content type: Review

    The accumulated evidence points to the microenvironment as the primary mediator of cellular fate determination. Comprised of parenchymal cells, stromal cells, structural extracellular matrix proteins, and sign...

    Authors: Patrick C. Sachs, Peter A. Mollica and Robert D. Bruno

    Citation: Journal of Biological Engineering 2017 11:34

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  2. Content type: Research

    Human induced pluripotent stem cells (hiPSCs) can form any tissue found in the body, making them attractive for regenerative medicine applications. Seeding hiPSC aggregates into biomaterial scaffolds can contr...

    Authors: Meghan E. Hall, Nima Khadem Mohtaram, Stephanie M. Willerth and Roderick Edwards

    Citation: Journal of Biological Engineering 2017 11:38

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  3. Content type: Research

    With additive manufacturing (AM) individual and biocompatible implants can be generated by using suitable materials. The aim of this study was to investigate the biological effects of polylactic acid (PLA) man...

    Authors: Matthias C. Wurm, Tobias Möst, Bastian Bergauer, Dominik Rietzel, Friedrich Wilhelm Neukam, Sandra C. Cifuentes and Cornelius von Wilmowsky

    Citation: Journal of Biological Engineering 2017 11:29

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  4. Content type: Review

    Recent advances in the expansion and directed pancreatogenic differentiation of human pluripotent stem cells (hPSCs) have intensified efforts to generate functional pancreatic islet cells, especially insulin-s...

    Authors: Elena F. Jacobson and Emmanuel S. Tzanakakis

    Citation: Journal of Biological Engineering 2017 11:21

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