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World Sepsis Day 2012

Fact: Sepsis kills 37,000 a year in the UK alone. This is more than bowel cancer, breast cancer and prostate cancer combined. It affects all groups of people from infants to the elderly and kills 1 in 3 of those who develop it. Yet, despite all this, sepsis is relatively unknown.

World Sepsis Day 2012: September 13th is the first ever World Sepsis Day, aimed at raising awareness of the disease across the world. Various events are being held across the world to mark the event and also raise awareness of this 'hidden' killer. Sepsis is a severe reaction to a microbial infection that results in an inflammatory response through the whole body. A vast number of sepsis cases follows clinical procedures, putting the onus of healthcare providers to take action to prevent sepsis.

BioMed Central journals Critical Care, Antimicrobial Resistance and Infection Control, BMC Anesthesiology, Scandinavian Journal of Trauma Resuscitation and Emergency Medicine, Annals of Clinical Microbiology and Antimicrobials and Virology Journal are all leading the way in making research on sepsis available on a global forum.

  1. Research

    Antibiotic resistance patterns and extended-spectrum β-lactamase production among Acinetobacter spp. isolated from an intensive care Unit of a hospital in Kerman, Iran

    The global increase in multidrug resistance of Acinetobacter spp. has created widespread problems in the treatment of patients in intensive care units (ICUs) of hospitals. To assess the sensitivity of Acinetobact...

    Mohammad Reza Shakibaie, Saied Adeli and Mohammad Hosain Salehi

    Antimicrobial Resistance and Infection Control 2012 1:1

    Published on: 13 October 2012

  2. Review

    Suspicion and treatment of severe sepsis. An overview of the prehospital chain of care

    Sepsis is a life-threatening condition where the risk of death has been reported to be even higher than that associated with the major complications of atherosclerosis, i.e. myocardial infarction and stroke. I...

    Johan Herlitz, Angela Bång, Birgitta Wireklint-Sundström, Christer Axelsson, Anders Bremer, Magnus Hagiwara, Anders Jonsson, Lars Lundberg, Björn-Ove Suserud and Lars Ljungström

    Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012 20:42

    Published on: 27 June 2012

  3. Research

    Prospective evaluation of the usefulness of C-reactive protein in the diagnosis of neonatal sepsis in a sub-Saharan African region

    Sepsis is one of the most common causes of morbidity and mortality in the newborn. Early diagnosis and treatment is vital to improve outcome. The present study was therefore carried out to determine the useful...

    Boma A West, Oliemen Peterside, Rosemary O Ugwu and Augusta U Eneh

    Antimicrobial Resistance and Infection Control 2012 1:22

    Published on: 1 June 2012

  4. Research

    Daptomycin exposure precedes infection and/or colonization with daptomycin non-susceptible enterococcus

    Daptomycin non-susceptible enterococci (DNSE) are emerging as an important cause of healthcare-associated infection, however little is known about the epidemiology of DNSE. At the University of Iowa Hospitals ...

    Jeremy C Storm, Daniel J Diekema, Jennifer S Kroeger, Sarah J Johnson and Birgir Johannsson

    Antimicrobial Resistance and Infection Control 2012 1:19

    Published on: 29 May 2012

  5. Research

    Antibacterial activity of statins: a comparative study of Atorvastatin, Simvastatin, and Rosuvastatin

    Statins have several effects beyond their well-known antihyperlipidemic activity, which include immunomodulatory, antioxidative and anticoagulant effects. In this study, we have tested the possible antimicrobi...

    Majed Masadeh, Nizar Mhaidat, Karem Alzoubi, Sayer Al-azzam and Ziad Alnasser

    Annals of Clinical Microbiology and Antimicrobials 2012 11:13

    Published on: 7 May 2012

  6. Original research

    High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study

    The level of soluble vascular endothelial growth factor receptor 1 (sVEGFR1) is increased in sepsis and strongly associated with disease severity and mortality. Endothelial activation and damage contribute to ...

    Sisse R Ostrowski, Anne Marie Sørensen, Nis A Windeløv, Anders Perner, Karen-Lise Welling, Michael Wanscher, Claus F Larsen and Pär I Johansson

    Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012 20:27

    Published on: 10 April 2012

  7. Research

    High load of multi-drug resistant nosocomial neonatal pathogens carried by cockroaches in a neonatal intensive care unit at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia

    Cockroaches have been described as potential vectors for various pathogens for decades; although studies from neonatal intensive care units are scarce. This study assessed the vector potential of cockroaches (...

    Birkneh Tilahun, Bogale Worku, Erdaw Tachbele, Simegn Terefe, Helmut Kloos and Worku Legesse

    Antimicrobial Resistance and Infection Control 2012 1:12

    Published on: 16 March 2012

  8. Editorial

    Ready for a world without antibiotics? The Pensières Antibiotic Resistance Call to Action

    Resistance to antibiotics has increased dramatically over the past few years and has now reached a level that places future patients in real danger. Microorganisms such as Escherichia coli and Klebsiella pneumoni...

    Jean Carlet, Vincent Jarlier, Stephan Harbarth, Andreas Voss, Herman Goossens and Didier Pittet

    Antimicrobial Resistance and Infection Control 2012 1:11

    Published on: 14 February 2012

  9. Review

    Critical care management of severe traumatic brain injury in adults

    Traumatic brain injury (TBI) is a major medical and socio-economic problem, and is the leading cause of death in children and young adults. The critical care management of severe TBI is largely derived from th...

    Samir H Haddad and Yaseen M Arabi

    Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012 20:12

    Published on: 3 February 2012

  10. Short report

    Antimicrobial stewardship in Scotland: impact of a national programme

    The Scottish Antimicrobial Prescribing Group (SAPG) was established by the Scottish Government in 2008 to lead the first national initiative to actively address antimicrobial stewardship. Healthcare associated...

    Dilip Nathwani, Jacqueline Sneddon, Andrea Patton and William Malcolm

    Antimicrobial Resistance and Infection Control 2012 1:7

    Published on: 3 February 2012

  11. Research

    Superantigen profiles of emm and emm-like typeable and nontypeable pharyngeal streptococcal isolates of South India

    The major virulence factors determining the pathogenicity of streptococcal strains include M protein encoded by emm and emm-like (emmL) genes and superantigens. In this study, the distribution of emm, emmL and su...

    Thangarajan Durai Anand, Thangamani Rajesh, Jeyaprakash Rajendhran and Paramasamy Gunasekaran

    Annals of Clinical Microbiology and Antimicrobials 2012 11:3

    Published on: 2 February 2012

  12. Research article

    Failure of available scoring systems to predict ongoing infection in patients with abdominal sepsis after their initial emergency laparotomy

    To examine commonly used scoring systems, designed to predict overall outcome in critically ill patients, for their ability to select patients with an abdominal sepsis that have ongoing infection needing relap...

    Oddeke van Ruler, Jordy JS Kiewiet, Kimberley R Boer, Bas Lamme, Dirk J Gouma, Marja A Boermeester and Johannes B Reitsma

    BMC Surgery 2011 11:38

    Published on: 23 December 2011

  13. Study protocol

    Early rehabilitation in sepsis: a prospective randomised controlled trial investigating functional and physiological outcomes The i-PERFORM Trial(Protocol Article)

    Patients with sepsis syndromes in comparison to general intensive care patients can have worse outcomes for physical function, quality of life and survival. Early intensive care rehabilitation can improve the ...

    Geetha Kayambu, Robert J Boots and Jennifer D Paratz

    BMC Anesthesiology 2011 11:21

    Published on: 31 October 2011

  14. Short report

    Isolation and characterization of a novel podovirus which infects burkholderia pseudomallei

    Burkholderia pseudomallei is a saprophytic soil bacterium and the etiological agent that causes melioidosis. It is naturally resistant to many antibiotics and therefore is difficult to treat. Bacteriophages may p...

    Jiraporn Gatedee, Kanyanan Kritsiriwuthinan, Edouard E Galyov, Jinyu Shan, Elena Dubinina, Narin Intarak, Martha RJ Clokie and Sunee Korbsrisate

    Virology Journal 2011 8:366

    Published on: 26 July 2011

  15. Research

    Epidemics of enterovirus infection in Chungnam Korea, 2008 and 2009

    Previously, we explored the epidemic pattern and molecular characterization of enteroviruses isolated in Chungnam, Korea from 2005 to 2006. The present study extended these observations to 2008 and 2009. In th...

    KyoungAh Baek, SangGu Yeo, BaeckHee Lee, KwiSung Park, JaeHyoung Song, JeeSuk Yu, InSoo Rheem, JaeKyung Kim, SeoYeon Hwang, YoungJin Choi, DooSung Cheon and JoonSoo Park

    Virology Journal 2011 8:297

    Published on: 13 June 2011