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World Sepsis Day 2012

Fact: Sepsis kills 37,000 a year in the UK alone. This is more than bowel cancer, breast cancer and prostate cancer combined. It affects all groups of people from infants to the elderly and kills 1 in 3 of those who develop it. Yet, despite all this, sepsis is relatively unknown.

World Sepsis Day 2012: September 13th is the first ever World Sepsis Day, aimed at raising awareness of the disease across the world. Various events are being held across the world to mark the event and also raise awareness of this 'hidden' killer. Sepsis is a severe reaction to a microbial infection that results in an inflammatory response through the whole body. A vast number of sepsis cases follows clinical procedures, putting the onus of healthcare providers to take action to prevent sepsis.

BioMed Central journals Critical Care, Antimicrobial Resistance and Infection Control, BMC Anesthesiology, Scandinavian Journal of Trauma Resuscitation and Emergency Medicine, Annals of Clinical Microbiology and Antimicrobials and Virology Journal are all leading the way in making research on sepsis available on a global forum.

  1. The global increase in multidrug resistance of Acinetobacter spp. has created widespread problems in the treatment of patients in intensive care units (ICUs) of hospitals. To assess the sensitivity of Acinetobact...

    Authors: Mohammad Reza Shakibaie, Saied Adeli and Mohammad Hosain Salehi
    Citation: Antimicrobial Resistance and Infection Control 2012 1:1
    Content type: Research Published on:

  3. Early diagnosis of sepsis and its differentiation from the noninfective SIRS is very important in order that treatment can be initiated in a timely and appropriate way. In this study we investigated standard h...

    Authors: Miroslav Durila, J Bronský, T Haruštiak, Alexander Pazdro, Marta Pechová and Karel Cvachovec
    Citation: BMC Anesthesiology 2012 12:12
    Content type: Research article Published on:

  4. Sepsis is a life-threatening condition where the risk of death has been reported to be even higher than that associated with the major complications of atherosclerosis, i.e. myocardial infarction and stroke. I...

    Authors: Johan Herlitz, Angela Bång, Birgitta Wireklint-Sundström, Christer Axelsson, Anders Bremer, Magnus Hagiwara, Anders Jonsson, Lars Lundberg, Björn-Ove Suserud and Lars Ljungström
    Citation: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012 20:42
    Content type: Review Published on:

  5. Severe sepsis is a medical emergency affecting up to 18 million individuals world wide, with an annual incidence of 750,000 in North America alone. Mortality ranges between 28-50% of those individuals stricken...

    Authors: Sarah M Perman, Munish Goyal and David F Gaieski
    Citation: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012 20:41
    Content type: Review Published on:

  6. Sepsis is one of the most common causes of morbidity and mortality in the newborn. Early diagnosis and treatment is vital to improve outcome. The present study was therefore carried out to determine the useful...

    Authors: Boma A West, Oliemen Peterside, Rosemary O Ugwu and Augusta U Eneh
    Citation: Antimicrobial Resistance and Infection Control 2012 1:22
    Content type: Research Published on:

  7. Daptomycin non-susceptible enterococci (DNSE) are emerging as an important cause of healthcare-associated infection, however little is known about the epidemiology of DNSE. At the University of Iowa Hospitals ...

    Authors: Jeremy C Storm, Daniel J Diekema, Jennifer S Kroeger, Sarah J Johnson and Birgir Johannsson
    Citation: Antimicrobial Resistance and Infection Control 2012 1:19
    Content type: Research Published on:

  8. Statins have several effects beyond their well-known antihyperlipidemic activity, which include immunomodulatory, antioxidative and anticoagulant effects. In this study, we have tested the possible antimicrobi...

    Authors: Majed Masadeh, Nizar Mhaidat, Karem Alzoubi, Sayer Al-azzam and Ziad Alnasser
    Citation: Annals of Clinical Microbiology and Antimicrobials 2012 11:13
    Content type: Research Published on:

  9. The level of soluble vascular endothelial growth factor receptor 1 (sVEGFR1) is increased in sepsis and strongly associated with disease severity and mortality. Endothelial activation and damage contribute to ...

    Authors: Sisse R Ostrowski, Anne Marie Sørensen, Nis A Windeløv, Anders Perner, Karen-Lise Welling, Michael Wanscher, Claus F Larsen and Pär I Johansson
    Citation: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012 20:27
    Content type: Original research Published on:

  11. Holins are a group of phage-encoded membrane proteins that control access of phage-encoded endolysins to the peptidoglycan, and thereby trigger the lysis process at a precise time point as the 'lysis clock'. S...

    Authors: Yibo Shi, Yaxian Yan, Wenhui Ji, Bin Du, Xiangpeng Meng, Hengan Wang and Jianhe Sun
    Citation: Virology Journal 2012 9:70
    Content type: Research Published on:

  12. Cockroaches have been described as potential vectors for various pathogens for decades; although studies from neonatal intensive care units are scarce. This study assessed the vector potential of cockroaches (...

    Authors: Birkneh Tilahun, Bogale Worku, Erdaw Tachbele, Simegn Terefe, Helmut Kloos and Worku Legesse
    Citation: Antimicrobial Resistance and Infection Control 2012 1:12
    Content type: Research Published on:

  13. Resistance to antibiotics has increased dramatically over the past few years and has now reached a level that places future patients in real danger. Microorganisms such as Escherichia coli and Klebsiella pneumoni...

    Authors: Jean Carlet, Vincent Jarlier, Stephan Harbarth, Andreas Voss, Herman Goossens and Didier Pittet
    Citation: Antimicrobial Resistance and Infection Control 2012 1:11
    Content type: Editorial Published on:

  14. Traumatic brain injury (TBI) is a major medical and socio-economic problem, and is the leading cause of death in children and young adults. The critical care management of severe TBI is largely derived from th...

    Authors: Samir H Haddad and Yaseen M Arabi
    Citation: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012 20:12
    Content type: Review Published on:

  15. The Scottish Antimicrobial Prescribing Group (SAPG) was established by the Scottish Government in 2008 to lead the first national initiative to actively address antimicrobial stewardship. Healthcare associated...

    Authors: Dilip Nathwani, Jacqueline Sneddon, Andrea Patton and William Malcolm
    Citation: Antimicrobial Resistance and Infection Control 2012 1:7
    Content type: Short report Published on:

  16. The major virulence factors determining the pathogenicity of streptococcal strains include M protein encoded by emm and emm-like (emmL) genes and superantigens. In this study, the distribution of emm, emmL and su...

    Authors: Thangarajan Durai Anand, Thangamani Rajesh, Jeyaprakash Rajendhran and Paramasamy Gunasekaran
    Citation: Annals of Clinical Microbiology and Antimicrobials 2012 11:3
    Content type: Research Published on:

  17. To examine commonly used scoring systems, designed to predict overall outcome in critically ill patients, for their ability to select patients with an abdominal sepsis that have ongoing infection needing relap...

    Authors: Oddeke van Ruler, Jordy JS Kiewiet, Kimberley R Boer, Bas Lamme, Dirk J Gouma, Marja A Boermeester and Johannes B Reitsma
    Citation: BMC Surgery 2011 11:38
    Content type: Research article Published on:

  18. Patients with sepsis syndromes in comparison to general intensive care patients can have worse outcomes for physical function, quality of life and survival. Early intensive care rehabilitation can improve the ...

    Authors: Geetha Kayambu, Robert J Boots and Jennifer D Paratz
    Citation: BMC Anesthesiology 2011 11:21
    Content type: Study protocol Published on:

  19. Burkholderia pseudomallei is a saprophytic soil bacterium and the etiological agent that causes melioidosis. It is naturally resistant to many antibiotics and therefore is difficult to treat. Bacteriophages may p...

    Authors: Jiraporn Gatedee, Kanyanan Kritsiriwuthinan, Edouard E Galyov, Jinyu Shan, Elena Dubinina, Narin Intarak, Martha RJ Clokie and Sunee Korbsrisate
    Citation: Virology Journal 2011 8:366
    Content type: Short report Published on:

  20. Previously, we explored the epidemic pattern and molecular characterization of enteroviruses isolated in Chungnam, Korea from 2005 to 2006. The present study extended these observations to 2008 and 2009. In th...

    Authors: KyoungAh Baek, SangGu Yeo, BaeckHee Lee, KwiSung Park, JaeHyoung Song, JeeSuk Yu, InSoo Rheem, JaeKyung Kim, SeoYeon Hwang, YoungJin Choi, DooSung Cheon and JoonSoo Park
    Citation: Virology Journal 2011 8:297
    Content type: Research Published on: