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Frontiers in Virology and COVID-19

As we continue to grapple the COVID-19 pandemic around the globe, the Society of Chinese Bioscientists in America-Virology Division and Cell & Bioscience have published a new series focused on virology and COVID-19.

While submissions can range from basic science to translational research to clinical applications, we especially welcome papers reporting new findings related to virus-host interaction, viral replication, and antiviral therapeutics. Preferred article types include original research articles, reviews, and short reports. Commentaries and Letters to the Editors may be considered for inclusion, pending Editorial approval.

Guest Editors: Dong-Yan Jin (University of Hong Kong), Zhi-Ming Zheng (NCI, National Institutes of Health), and Shan-Lu Liu (The Ohio State University)
 

  1. Artemisia argyi (A. argyi), also called Chinese mugwort, has been widely used to control pandemic diseases for thousands of years since ancient China due to its anti-microbial infection, anti-allergy, and anti-in...

    Authors: Fang-Ju Cheng, Chien-Yi Ho, Tzong-Shiun Li, Yeh Chen, Yi-Lun Yeh, Ya-Ling Wei, Thanh Kieu Huynh, Bo-Rong Chen, Hung-Yu Ko, Chen-Si Hsueh, Ming Tan, Yang-Chang Wu, Hui-Chi Huang, Chih-Hsin Tang, Chia-Hung Chen, Chih-Yen Tu…
    Citation: Cell & Bioscience 2023 13:118
    Content type: Research Published on:

  2. Neutralizing antibodies are approved drugs to treat coronavirus disease-2019 (COVID-19) patients, yet mutations in severe acute respiratory syndrome coronavirus (SARS-CoV-2) variants may reduce the antibody ne...

    Authors: Lili Li, Meiling Gao, Peng Jiao, Shulong Zu, Yong-qiang Deng, Dingyi Wan, Yang Cao, Jing Duan, Saba R Aliyari, Jie Li, Yueyue Shi, Zihe Rao, Cheng-feng Qin, Yu Guo, Genhong Cheng and Heng Yang
    Citation: Cell & Bioscience 2022 12:63
    Content type: Research Published on:

  3. The Ilheus virus (ILHV) is an encephalitis associated arthropod-borne flavivirus. It was first identified in Ilheus City in the northeast Brazil before spreading to a wider geographic range. No specific vaccin...

    Authors: De-Ping Wang, Mei-Yue Wang, Yong-Mei Li, Wen Shu, Wen Cui, Fang-Ying Jiang, Xin Zhou, Wen-Ming Wang and Ji-Min Cao
    Citation: Cell & Bioscience 2022 12:44
    Content type: Research Published on:

  4. SARS-CoV-2 is the causative agent of COVID-19. Overproduction and release of proinflammatory cytokines are the underlying cause of severe COVID-19. Treatment of this condition with JAK inhibitors is a double-e...

    Authors: Sin-Yee Fung, Kam-Leung Siu, Huayue Lin, Ching-Ping Chan, Man Lung Yeung and Dong-Yan Jin
    Citation: Cell & Bioscience 2022 12:36
    Content type: Research Published on:

  6. One of coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused coronavirus disease 2019 (COVID-19) pandemic and threatened worldwide. However, therapy for COVID-19 has rarely been...

    Authors: Sang R. Lee, Jeong Yeon Roh, Jihoon Ryu, Hyun-Jin Shin and Eui-Ju Hong
    Citation: Cell & Bioscience 2022 12:7
    Content type: Research Published on:

  7. Although multiple studies have demonstrated a role for exosomes during virus infections, our understanding of the mechanisms by which exosome exchange regulates immune response during viral infections and affe...

    Authors: Farhang Alem, Adeyemi A. Olanrewaju, Samson Omole, Heather E. Hobbs, Noor Ahsan, Graham Matulis, Christine A. Brantner, Weidong Zhou, Emanuel F. Petricoin, Lance A. Liotta, Massimo Caputi, Sina Bavari, Yuntao Wu, Fatah Kashanchi and Ramin M. Hakami
    Citation: Cell & Bioscience 2021 11:220
    Content type: Research Published on:

  8. In February 2020, we highlighted the top nine important research questions on SARS-CoV-2 and COVID-19 concerning virus transmission, asymptomatic and presymptomatic virus shedding, diagnosis, treatment, vaccin...

    Authors: Kit-San Yuen, Zi-Wei Ye, Sin-Yee Fung, Pak-Hin Hinson Cheung, Chi-Ping Chan and Dong-Yan Jin
    Citation: Cell & Bioscience 2021 11:215
    Content type: Viewpoint Published on:

  9. Chickens, important food animals and model organisms, are susceptible to many RNA viruses that invade via the nasal cavity. To determine the nasal entry site of the virus and clarify why avians are susceptible...

    Authors: Abid Ullah Shah, Yuchen Li, Wei Ouyang, Zhisheng Wang, Jinjiao Zuo, Song Shi, Qinghua Yu, Jian Lin and Qian Yang
    Citation: Cell & Bioscience 2021 11:212
    Content type: Research Published on:

  10. The ongoing COVID-19 pandemic has resulted in 185 million recorded cases and over 4 million deaths worldwide. Several COVID-19 vaccines have been approved for emergency use in humans and are being used in many...

    Authors: Huibi Cao, Juntao Mai, Zhichang Zhou, Zhijie Li, Rongqi Duan, Jacqueline Watt, Ziyan Chen, Ranmal Avinash Bandara, Ming Li, Sang Kyun Ahn, Betty Poon, Natasha Christie-Holmes, Scott D. Gray-Owen, Arinjay Banerjee, Karen Mossman, Rob Kozak…
    Citation: Cell & Bioscience 2021 11:202
    Content type: Research Published on:

  11. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly transmissible and has caused a pandemic named coronavirus disease 2019 (COVID-19), which has quickly spread worldwide. Although several th...

    Authors: Gangan Yan, Dongsheng Li, Yuan Lin, Zhenghao Fu, Haiyan Qi, Xiaoping Liu, Jing Zhang, Shuyi Si and Yunyu Chen
    Citation: Cell & Bioscience 2021 11:199
    Content type: Methodology Published on:

  12. There is currently a critical need to determine the efficacy of SARS-CoV-2 vaccination for immunocompromised patients. In this study, we determined the neutralizing antibody response in 160 cancer patients dia...

    Authors: Cong Zeng, John P. Evans, Sarah Reisinger, Jennifer Woyach, Christina Liscynesky, Zeinab El Boghdadly, Mark P. Rubinstein, Karthik Chakravarthy, Linda Saif, Eugene M. Oltz, Richard J. Gumina, Peter G. Shields, Zihai Li and Shan-Lu Liu
    Citation: Cell & Bioscience 2021 11:197
    Content type: Letter to the Editor Published on:

  13. Methamphetamine (METH), a potent addictive psychostimulant, is highly prevalent in HIV-infected individuals. Clinically, METH use is implicated in alteration of immune system and increase of HIV spread/replica...

    Authors: Yu Liu, Feng-Zhen Meng, Xu Wang, Peng Wang, Jin-Biao Liu, Wen-Hui Hu, Won-Bin Young and Wen-Zhe Ho
    Citation: Cell & Bioscience 2021 11:194
    Content type: Research Published on:

  15. Coronavirus disease 2019 (COVID-19) is an emerging infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and has posed a serious threat to global health. Here, we syste...

    Authors: Xu Pan, Xin Li, Shangwei Ning and Hui Zhi
    Citation: Cell & Bioscience 2021 11:171
    Content type: Letter to the Editor Published on:

  16. As the COVID-19 pandemic rages on, the new SARS-CoV-2 variants have emerged in the different regions of the world. These newly emerged variants have mutations in their spike (S) protein that may confer resista...

    Authors: Jinbiao Liu, Brittany H. Bodnar, Fengzhen Meng, Adil I. Khan, Xu Wang, Sami Saribas, Tao Wang, Saroj Chandra Lohani, Peng Wang, Zhengyu Wei, Jinjun Luo, Lina Zhou, Jianguo Wu, Guangxiang Luo, Qingsheng Li, Wenhui Hu…
    Citation: Cell & Bioscience 2021 11:168
    Content type: Research Published on:

  17. Analysis of viral protein–protein interactions is an essential step to uncover the viral protein functions and the molecular mechanism for the assembly of a viral protein complex. We employed a mammalian two-h...

    Authors: Yiling Jiang, Kuijie Tong, Roubin Yao, Yuanze Zhou, Hanwen Lin, Liubing Du, Yunyun Jin, Liu Cao, Jingquan Tan, Xing-Ding Zhang, Deyin Guo, Ji-An Pan and Xiaoxue Peng
    Citation: Cell & Bioscience 2021 11:140
    Content type: Research Published on:

  18. The ongoing coronavirus disease-2019 (COVID-19) pandemic, caused by a novel coronavirus termed severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that is closely related to SARS-CoV, poses a grave th...

    Authors: Kui Li, Yang Shen, Mark A. Miller, Jennifer Stabenow, Robert W. Williams and Lu Lu
    Citation: Cell & Bioscience 2021 11:137
    Content type: Letter to the Editor Published on:

  20. Our previous studies have shown that combining the antiviral lectin GRFT and the pan-CoV fusion inhibitory peptide EK1 results in highly potent inhibitory activity against SARS-CoV-2 infection. In this study, ...

    Authors: Yanxing Cai, Wei Xu, Jiayi Tang, Najing Cao, Qiaoshuai Lan, Lu Lu and Shibo Jiang
    Citation: Cell & Bioscience 2021 11:128
    Content type: Research Published on:

  22. The sodium taurocholate cotransporting polypeptide (NTCP) is a functional receptor for hepatitis B virus (HBV). NTCP-reconstituted human hepatoma cells support HBV infection, but the infection is suboptimal an...

    Authors: Xinlei Li, Zhaohui Xu, Bidisha Mitra, Minghang Wang, Haitao Guo and Zongdi Feng
    Citation: Cell & Bioscience 2021 11:123
    Content type: Research Published on:

  23. Zika virus (ZIKV) infection and ZIKV epidemic have been continuously spreading silently throughout the world and its associated microcephaly and other serious congenital neurological complications poses a sign...

    Authors: Lili Li, Yueyue Shi, Sirui Li, Junxiao Liu, Shulong Zu, Xin Xu, Meiling Gao, Nina Sun, Chaohu Pan, Linan Peng, Heng Yang and Genhong Cheng
    Citation: Cell & Bioscience 2021 11:116
    Content type: Research Published on:

  26. The ongoing global pandemic of coronavirus disease 2019 (COVID-19) has resulted in the infection of over 128 million people and has caused over 2.8 million deaths as of April 2021 in more than 220 countries an...

    Authors: Brian Hetrick, Dongyang Yu, Adeyemi A. Olanrewaju, Linda D. Chilin, Sijia He, Deemah Dabbagh, Ghaliah Alluhaibi, Yuan-Chun Ma, Lewis A. Hofmann, Ramin M. Hakami and Yuntao Wu
    Citation: Cell & Bioscience 2021 11:100
    Content type: Research Published on:

  27. Poxviruses comprise many members that infect both vertebrate and invertebrate animals, including humans. Despite the eradication of the historically notorious smallpox, poxviruses remain significant public hea...

    Authors: Zhilong Yang, Mark Gray and Lake Winter
    Citation: Cell & Bioscience 2021 11:96
    Content type: Review Published on:

  28. In the urgent campaign to develop therapeutics against SARS-CoV-2, natural products have been an important source of new lead compounds.

    Authors: Zinuo Chen, Qinghua Cui, Laura Cooper, Pin Zhang, Hyun Lee, Zhaoyu Chen, Yanyan Wang, Xiaoyun Liu, Lijun Rong and Ruikun Du
    Citation: Cell & Bioscience 2021 11:45
    Content type: Research Published on:

    The Letter to the Editor to this article has been published in Cell & Bioscience 2022 12:65

  29. The angiotensin-converting enzyme 2 (ACE2) is the host functional receptor for the new virus SARS-CoV-2 causing Coronavirus Disease 2019. ACE2 is expressed in 72 different cell types. Some factors that can aff...

    Authors: Miriam Marlene Medina-Enríquez, Sandra Lopez-León, José Alberto Carlos-Escalante, Zuleika Aponte-Torres, Angelica Cuapio and Talia Wegman-Ostrosky
    Citation: Cell & Bioscience 2020 10:148
    Content type: Review Published on:

  30. Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. Here we highlight nine most important research questions concer...

    Authors: Kit-San Yuen, Zi -Wei Ye, Sin-Yee Fung, Chi-Ping Chan and Dong-Yan Jin
    Citation: Cell & Bioscience 2020 10:40
    Content type: Research Highlight Published on: