Sarah Bondos,Texas A&M University, USA
A. K. Dunker, Indiana University, USA
Vladimir Uversky, University of South Florida, USA
Cell Communications and Signaling invites you to submit to our new thematic series: The roles of intrinsically disordered proteins and regions (IDPs and IDRs) in cell communication and cell signaling.
Intrinsically disordered proteins and regions (IDPs and IDRs) are of crucial importance to cell communication and signaling. IDRs increase the complexity of regulatory networks by combining a wider range of protein interactions with alternative splicing and post-translational modification to elicit unique cellular outcomes. Indeed, harnessing the power of cell signaling for applications in biotechnology will require understanding and engineering the roles of IDPs and IDRs in the various signaling pathways and in the environments in which they operate. Our upcoming special issue explores many cell signaling pathways and their applications in light of recent advances in the field of intrinsic disorder. Topics include chemical signaling, sensing and responding to temperature, pressure, and light. Also included are the roles of disorder in designing sensors, switches, and scaffolds for tissue engineering.
We welcome the submission of additional manuscripts that describe the functional roles of IDPs or IDRs in cell communication and signaling.