Can "developed" countries learn from the lessons of "developing" countries? How can we move away from the fatuous ideas associated with being labelled a 'developed' or 'developing' country? These are but a few questions that Globalization and Health new thematic series, 'Reverse innovation in global health systems: learning from low-income countries' will address to enhance our understanding in this subject. The series aims to move beyond the narrow constraints of traditional thinking to promote bi-directional learning that challenges and rethinks traditional practice within global health systems. Submissions are being accepted for on-going publication.