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Research highlights

Recent Research highlights published in Genome Biology

This list will be updated with all our new Research highlights. Genome Biology publishes Research highlights that are open access and therefore free to read and share.

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  1. Content type: Research Highlight

    Balancing selection maintains variation for evolution. A recent study investigated the extent of balancing selection in two Brassicaceae species and highlighted its importance for adaptation.

    Authors: Baosheng Wang and Thomas Mitchell-Olds

    Citation: Genome Biology 2017 18:231

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  2. Content type: Research Highlight

    Epigenetic profiling in diploid, allopolyploid, and domesticated cotton shows that despite most DNA methylation being conserved and stably inherited, alterations likely due to hybridization and domestication a...

    Authors: Scott A. Jackson

    Citation: Genome Biology 2017 18:117

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  3. Content type: Research Highlight

    Epigenetic clocks provide powerful tools to evaluate nutritional, hormonal, and genetic effects on aging. What can we learn from differences between species in how these clocks tick?

    Authors: Wolfgang Wagner

    Citation: Genome Biology 2017 18:107

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  4. Content type: Research Highlight

    Two recent studies demonstrate the power of integrating tumor genotype information with epigenetic and proteomic studies to discover potential therapeutic targets in breast cancer.

    Authors: Gabriel J. Sandoval and William C. Hahn

    Citation: Genome Biology 2017 18:95

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  5. Content type: Research Highlight

    A recently published study in Genome Biology shows that cells isolated from cryopreserved tissues are a reliable source of genetic material for single-cell RNA-sequencing experiments.

    Authors: Felipe A. Vieira Braga, Sarah A. Teichmann and Michael J. T. Stubbington

    Citation: Genome Biology 2017 18:54

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  6. Content type: Research Highlight

    Selection-free genome editing using Cas9 ribonucleoprotein embryo bombardment has been achieved for maize and wheat. This is a breakthrough that should make new breeding technologies more acceptable for worldw...

    Authors: Felix Wolter and Holger Puchta

    Citation: Genome Biology 2017 18:43

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  7. Content type: Research Highlight

    Tumor cells have to overcome challenges in the host tissue microenvironment to metastasize successfully to distant organs. In a recent Nature study, a genome-wide functional screen demonstrated that deficiency of...

    Authors: Toni Celià-Terrassa and Yibin Kang

    Citation: Genome Biology 2017 18:31

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  8. Content type: Research Highlight

    Alternative splice isoforms are common and important and have been shown to impact many human diseases. A new study by Nellore et al. offers a comprehensive study of splice junctions in humans by re-analyzing ...

    Authors: Christelle Robert and Mick Watson

    Citation: Genome Biology 2016 17:265

    Published on:

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