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Post-Traumatic Stress Disorder (PTSD): Biopsychosocial Translational Research and Everyday Practice

Edited by: Prof. Alexander V. Libin

Posttraumatic Stress Disorder (PTSD) is a complex of trauma triggered mental health conditions caused by experiencing intolerable amount of stress. The emotional and social-behavioral changes following PTSD are acknowledged to be among the most devastating consequences of traumatic experience and are strongly associated with problems in daily functioning and an unfavorable social outcome. PTSD diagnosis in both military and civilian populations is highly correlated with behavioral symptoms such as social dysfunction across multiple domains on community integration, including loss of important relationships, disrupted family life, poor work-related quality of life, and reduced individual activity.

PTSD is often complicated by multiple neurologic co-morbidities and functional disabilities such as those caused by Traumatic Brain Injury (TBI)/Polytrauma, and further convoluted by substance abuse, suicidal ideation, chronic depression and anxiety, and fragile social supports.

Studies emphasize the dramatic impact of PTSD and associated complex medical conditions among both active duty troops, as well as difficulties that such impairments present for returning service members. There is mounting evidence to suggest that executive dysfunction and emotional dysregulation resulting from a CNS insult causes both short-term and long-term consequences causing poor goal-directed behavior, impaired decision making, and significant decrease in independent functioning. Timely detection of the disabling impact of PTSD on human activities is necessary for both the accurate diagnosis and individual-tailoring of rehabilitation processes aimed at recovery of independent function.

In this thematic series, we would like to demonstrate how medical and rehabilitation research translates through best practices in interventional psychosocial rehabilitation, physical and psychological health interface, and assessment of relevant outcomes to the ultimate goal of clinical practice: facilitation of successful social reintegration of fractured by trauma individuals.

This series was published in Military Medical Research

  1. Sleep disorders frequently occur in posttraumatic stress disorder (PTSD) patients. Chronic insomnia is a common feature of and criteria for the diagnosis of PTSD. Another sleep disorder, obstructive sleep apne...

    Authors: Barry J. Krakow, Natalia D. McIver, Jessica J. Obando and Victor A. Ulibarri
    Citation: Military Medical Research 2019 6:15
  2. This study examines the relationship between coping strategies and symptoms of anxiety or depression among Dutch servicemembers deployed to Afghanistan.

    Authors: Loes G. M. de Kruijff, Olivia R. M. Moussault, Marie-Christine J. Plat, Rigo Hoencamp and Peter van der Wurff
    Citation: Military Medical Research 2019 6:9
  3. The impact of combat operations in Iraq and Afghanistan on the incidence of post-traumatic stress disorder (PTSD) in military service members has been poorly quantified. The purpose of this study was to examin...

    Authors: Kenneth L. Cameron, Rodney X. Sturdivant and Susan P. Baker
    Citation: Military Medical Research 2019 6:8
  4. Posttraumatic stress disorder (PTSD) is a chronic impairment disorder that occurs after exposure to traumatic events. This disorder can result in a disturbance to individual and family functioning, causing sig...

    Authors: Xue-Rong Miao, Qian-Bo Chen, Kai Wei, Kun-Ming Tao and Zhi-Jie Lu
    Citation: Military Medical Research 2018 5:32
  5. Large numbers of post-deployment U.S. veterans are diagnosed with post-traumatic stress disorder (PTSD) and/or traumatic brain injury (TBI), leading to an urgent need for effective interventions to reduce symp...

    Authors: Rebecca A. Johnson, David L. Albright, James R. Marzolf, Jessica L. Bibbo, Hayley D. Yaglom, Sandra M. Crowder, Gretchen K. Carlisle, Amy Willard, Cynthia L. Russell, Karen Grindler, Steven Osterlind, Marita Wassman and Nathan Harms
    Citation: Military Medical Research 2018 5:3
  6. Military-related post-traumatic stress (PTS) is associated with numerous symptom clusters and diminished autonomic cardiovascular regulation. High-resolution, relational, resonance-based, electroencephalic mir...

    Authors: Catherine L. Tegeler, Lee Gerdes, Hossam A. Shaltout, Jared F. Cook, Sean L. Simpson, Sung W. Lee and Charles H. Tegeler
    Citation: Military Medical Research 2017 4:38
  7. Post-traumatic stress disorder (PTSD) is a disabling, potentially chronic disorder that is characterized by re-experience and hyperarousal symptoms as well as the avoidance of trauma-related stimuli. The distr...

    Authors: Deborah A. Perlick, Frederic J. Sautter, Julia J. Becker-Cretu, Danielle Schultz, Savannah C. Grier, Alexander V. Libin, Manon Maitland Schladen and Shirley M. Glynn
    Citation: Military Medical Research 2017 4:21
  8. The critically ill or injured patient undergoing military medical evacuation may require emergent intubation. Intubation may be life-saving, but it carries risks. The novice or infrequent laryngoscopist has a ...

    Authors: Matthew C. Wallace, SSgt Tyler Britton, Robbie Meek, Sharon Walsh-Hart, Col Todd E. Carter and Steven J. Lisco
    Citation: Military Medical Research 2017 4:20
  9. The prevalence of ischemia on nuclear myocardial perfusion imaging (MPI) has been decreasing. Recent research has questioned the benefit of invasive revascularization for patients with moderate to severe ische...

    Authors: David E. Winchester, Alexander J. Bolanos, Anita Wokhlu, Rebecca J. Beyth and Leslee J. Shaw
    Citation: Military Medical Research 2017 4:12