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Call for papers - Plant synthetic biology: advances in fundamental research and applications

Guest Editors

Jemaa Essemine, PhD, Centre for Excellence in Molecular Plant Science, China
Saroj Kumar Sah, PhD, Brookhaven National Laboratory, USA
Qinlong Zhu, PhD, South China Agricultural University, China

Submission Status: Open   |   Submission Deadline: 31 January 2025

BMC Plant Biology invites submissions to the Collection Plant synthetic biology: advances in fundamental research and applications. This Collection aims to gather fundamental and applied research in plant synthetic biology, covering aspects such as plant yield and resilience enhancement, plant metabolic engineering, genetic engineering of synthetic plastomes and plant systems for the production of high-value bioactive compounds, agricultural bioengineering, and plant synthetic biology innovations applied to sustainable agriculture, among other research questions.

New Content ItemThis Collection supports and amplifies research related to SDG 2: Zero Hunger

Meet the Guest Editors

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Jemaa Essemine, PhD, Centre for Excellence in Molecular Plant Science, China

Dr Essemine is a Research associate at the Chinese Academy of Sciences specializing in plant molecular genetics, particularly in gene-editing technologies like CRISPR-Cas and base editing. His research encompasses diverse areas of plant science, including plant physiology, biochemistry, photosynthesis, biophysics, epigenetics, and synthetic biology. He utilizes advanced techniques such as integrative metabolomics and transcriptomics to identify key genes responsible for genetic variation and regulation. Dr Essemine's work highlights the intricate interplay between the genome and epigenome, as well as the integration of various biological systems and processes. Synthetic biology plays a crucial role in his research, enabling the design and engineering of climate-smart plants and stress-resilient crops to enhance overall productivity. He completed his PhD in Biological Sciences through a collaboration between University of Tunis El Manar (UTM) in Tunisia and the University du Quebec à Trois-Rivières (UQTR) in Canada. Following this, he pursued postdoctoral research before assuming a tenure-track researcher associate position with the Chinese Academy of Sciences (CAS). Dr Essemine is actively involved in the scientific community, serving as an editor or reviewer for several high-impact journals. His contributions include identifying genes that control cyclic electron flow (CEF) in rice leaves, which has significant implications for understanding plant energy metabolism.

Saroj Kumar Sah, PhD,  Brookhaven National Laboratory, USA

Dr Sah holds a PhD in Molecular Biology from Mississippi State University, USA, with a focus on plant molecular biology and plant physiology. His research investigates genes and their metabolic roles, particularly in plant resilience under abiotic stresses like drought, heat, and UV radiation. At the Pennsylvania State University, his postdoctoral work centered on understanding the regulatory mechanisms controlling cell identity in xylem cells, particularly during fiber and pith cell differentiation in Arabidopsis thaliana. Currently based at Brookhaven National Laboratory, Dr Sah employs a multidisciplinary approach, integrating molecular genetics, cell biology, biochemistry, and physiology to explore the complex regulatory network governing lipid metabolism, homeostasis, and storage. Dr Sah's expertise spans plant tissue cultures, genetic transformation, genome editing, proteomics, and bioinformatics. He has made significant contributions to the field with over 20 research articles in prestigious journals, along with book chapters and proceedings. Beyond research, Dr Sah is President of Nexus Institute of Research and Innovation USA and also holds the position of Principal Investigator at Nexus Institute of Research and Innovation (NIRI), Nepal.

Qinlong Zhu, PhD, South China Agricultural University, China

Dr Zhu is a professor of plant molecular biology and biotechnology at South China Agricultural University and previously served as a visiting associate professor at Cornell University (USA). His research focuses on utilizing plant synthetic biology strategies to develop new functional food crops by synthesizing bioactive compounds and improving nutritional quality. His research program is centered on developing genetic engineering tools for plant biosynthetic biology and their breeding applications. Dr Zhu and his colleagues have developed the TransGene Stacking systems for multigene assembly and transformation, as well as genome editing systems for plant metabolic pathway regulation and precision targeted breeding. Using these tools, a series of new functional food crops, such as "purple endosperm rice" and "astaxanthin rice", have been successfully developed by de novo biosynthesizing anthocyanins and astaxanthin in rice endosperm, respectively.

About the Collection

Plant synthetic biology is an emerging, interdisciplinary field that integrates engineering principles with plant molecular biology to design and develop new plant-based devices and biological systems, or re-engineer existing ones. This research field can have a high impact on traditional crop improvement and enable the development of novel bioproduction processes. Plant synthetic biology approaches hold great promise and potential to revolutionize fundamental and applied research for instance on crop yield improvement and climate-resilient/climate-smart crops, plant metabolism engineering, plant-based biotechnology and biomolecule production, agricultural bioengineering, and food production.

Recent advances in this area have demonstrated the successful engineering of plant systems for the production of high-value compounds, including vaccines, glycoproteins, and nutraceuticals. Moreover, the design and engineering of synthetic plastomes have expanded the possibilities for targeted metabolic engineering in plants. Overall, plant synthetic biology research could have transformative applications in sustainable agriculture, biopharmaceutical and nutraceutical production, and development of plant biofactories for the scalable production of valuable compounds.

In support of research related to the UN Sustainable Development Goal SDG 2: ‘Zero Hunger’, promoting food security and sustainable agricultural practices, BMC Plant Biology announces the launch of the Collection Plant synthetic biology: advances in fundamental research and applications. This Collection aims to gather fundamental and applied research in plant synthetic biology, covering aspects such as plant yield and resilience enhancement, plant metabolic engineering, genetic engineering of synthetic plastomes and plant systems for the production of high-value bioactive compounds, agricultural bioengineering, and plant synthetic biology innovations applied to sustainable agriculture. We invite researchers and experts in the field to submit research articles that explore, but are not limited to, the following topics:

  • Synthetic biology approaches for improving crop photosynthesis, yield and abiotic stress tolerance
  • Plant synthetic biology approaches for developing climate-smart plants
  • Applications of plant synthetic biology for crop breeding
  • Advances in synthetic carbon-conserving pathways and carbon metabolism engineering to improve crop yield
  • Plastid metabolic engineering
  • Advances and characterization of genetic parts and circuits for plant synthetic biology
  • Advances in DNA assembly, multigene stacking and genome editing for plant synthetic biology
  • Synthetic memory circuits for plant cell reprogramming and applications
  • CRISPR/Cas gene editing systems and plant functional genomics applied to plant synthetic biology approaches
  • Plant synthetic biology innovations: from laboratory to field applications
  • Plant synthetic biology applications in sustainable agriculture
  • Plant synthetic biology for recombinant protein production
  • Designing and engineering synthetic plastomes for the synthesis of high-value bioactive compounds
  • Development and engineering of metabolic devices for the production of biomolecules, nutraceuticals and pharmaceuticals
  • Plant biofactories for vaccine and antibody production
  • Plant molecular farming for recombinant biopharmaceutical production and biorefining


Image credit: © Seventyfour / stock.adobe.com

There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Plant synthetic biology: advances in fundamental research and applications" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.