Skip to content

Advertisement

You're viewing the new version of our site. Please leave us feedback.

Learn more

Prions

Prions are infectious agents that are responsible for a number of neurodegenerative diseases, known as Transmissible Spongiform Encephalopathies (TSEs), including Bovine Spongiform Encephalopathy (BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in humans. Prion diseases can be genetic, infectious, or sporadic, and they all involve modification of the prion protein (PrP). Here we present a compilation of manuscripts on various aspects of TSEs and their causative agents.

Prof Alun Williams

  1. Content type: Short Report

    Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) of cervids including white-tailed (Odocoileus virginianus) and mule deer (Odocoileus hemionus), Rocky Mountain elk (Cervus elaphus ...

    Authors: Stephen N White, Terry R Spraker, James O Reynolds and Katherine I O'Rourke

    Citation: BMC Research Notes 2010 3:314

    Published on:

  2. Content type: Short Report

    Routine rapid testing for Bovine Spongiform Encephalopathy (BSE) has highlighted some problems with BSE rapid test performance, the most significant being the number of initially reactive samples and the false...

    Authors: Daniela Meloni, Katia Varello, Marzia Pezzolato, Elsa Manzardo, Maria C Cavarretta, Francesco Ingravalle, Maria Caramelli and Elena Bozzetta

    Citation: BMC Research Notes 2010 3:193

    Published on:

  3. Content type: Short Report

    The transmissible spongiform encephalopathies (TSEs) comprise a group of fatal degenerative neurological diseases in humans and other mammals. After infection, the cellular prion protein isoform PrPC is converted...

    Authors: Michael J Taheny, Nerik Izkhakov, Alexander A Vostrov and Wolfgang W Quitschke

    Citation: BMC Research Notes 2009 2:178

    Published on:

  4. Content type: Short Report

    Transmissible spongiform encephalopathies (TSEs) are a group of fatal neurodegenerative diseases caused by novel infectious agents referred to as prions. Prions appear to be composed primarily, if not exclusiv...

    Authors: Christopher J Johnson, PUPA Gilbert, Debbie McKenzie, Joel A Pedersen and Judd M Aiken

    Citation: BMC Research Notes 2009 2:121

    Published on:

  5. Content type: Short Report

    Prions, the infectious agents that cause transmissible spongiform encephalopathies (TSEs), are relatively resistant to destruction by physical, enzymatic, and chemical treatments. Hydrolysis in boiling saturat...

    Authors: Justin J Greenlee, Eric M Nicholson, Amir N Hamir, Gary P Noyes, Mark T Holtzapple and Marcus E Kehrli Jr

    Citation: BMC Research Notes 2008 1:99

    Published on:

  6. Content type: Technical Note

    Classical and atypical bovine spongiform encephalopathies (BSEs) are cattle prion diseases. Distinct bovine prion gene (PRNP) alleles have been associated with classical and atypical BSE susceptibility. However, ...

    Authors: Michael L Clawson, Michael P Heaton, John W Keele, Timothy PL Smith, Gregory P Harhay, Juergen A Richt and William W Laegreid

    Citation: BMC Research Notes 2008 1:32

    Published on:

Advertisement